Current Topics in Cellular Regulation
- 1st Edition, Volume 15 - December 28, 1979
- Imprint: Academic Press
- Editors: Bernard L. Horecker, Earl R. Stadtman
- Language: English
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 0 3 7 1 - 3
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 1 7 1 4 - 7
Current Topics in Cellular Regulation, Volume 15 deliberates the basic mechanisms involved in the regulation of diverse cellular activities. This book discusses the kinetics and… Read more
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Request a sales quoteCurrent Topics in Cellular Regulation, Volume 15 deliberates the basic mechanisms involved in the regulation of diverse cellular activities. This book discusses the kinetics and thermodynamics of cGMP binding to G-kinase, activation of cyclic nucleotide phosphodiesterase, and polymeric forms of phosphofructokinase. The genetic control of pentose phosphate pathway enzymes in drosophila, discrepancies in the interpretation of the ODC assay, and comparison of chemotaxis in leukocytes and other cells are also elaborated. This publication likewise covers the biochemical aspects of neurosecretion and neurophysin-neurohormone complexes. This volume is valuable to biologists and researchers concerned with advances in the general area of cellular regulation.
List of Contributors
Guanosine 3′,5′-Monophosphate-Dependent Protein Kinase
I. Introduction
II. Structure and Regulation of G-Kinase
III. Kinetics and Thermodynamics of cGMP Binding to G-Kinase
IV. G-Kinase Activity
V. A Hypothesis Concerning the Structures of G-Kinase and A-Kinase
References
Calmodulin and Its Role in the Second-Messenger System
I. Introduction
II. General Background
III. Activation of Cyclic Nucleotide Phosphodiesterase
IV. Other Regulatory Activities
V. Physiological Roles
VI. Evolutionary Studies
References
Phosphofructokinase: Structure and Function
I. Introduction
II. Structural Properties
III. Polymeric Forms of Phosphofructokinase
IV. Ligand Binding to Phosphofructokinase
V. Allosteric Kinetics
VI. Cold Lability of Rabbit Muscle Phosphofructokinase
VII. Mechanism of the Reaction
VIII. Enzyme Modification
IX. Ligand-Induced Conformational Changes
X. Alternative Modes of Enzyme Regulation
References
Genetic Control of Pentose Phosphate Pathway Enzymes in Drosophila
I. Introduction
II. The Pathway
III. The Structural Genes
IV. Genetic Regulatory Effects
V. Metabolic Regulatory Effects
VI. Concluding Remarks
References
The Regulation and Function of Ornithine Decarboxylase and of the Polyamines
I. Introduction
II. Discrepancies in the Interpretation of the ODC Assay
III. Functions of Polyamines
IV The "Metabolic State" of the Cell and the "External Setting V. The Experimental Systems
VI. Mechanisms That Alter ODC Activity
VII. The Dynamic State of Polyamines in the Normal and Pathologic State
VIII. An Overview of ODC Regulation
IX. Concluding Remarks
References
Biochemistry of Phagocyte Chemotaxis
I. Introduction
II. Comparison of Chemotaxis in Leukocytes and Other Cells
III. Assay of Chemotaxis
IV. The Chemoattractants: Sensing the Signal
V. Transduction of the Chemotactic Signal
VI. Effector Processes: Sustained Locomotion
VII. Concluding Remarks
References
Biochemical Aspects of Neurosecretion: Neurophysin-Neurohypophyseal Hormone Complexes
I. Introduction
II. Neurohormones and Neurophysins: Structural Features
III. Neurophysin-Neurohormone Complexes—In Vitro Studies
IV. Neurophysin-Neurohormone Complexes—In Vivo Studies
V. Concluding Remarks
References
Subject Index
Correction to Volume 9
Contents of Previous Volumes
- Edition: 1
- Volume: 15
- Published: December 28, 1979
- No. of pages (eBook): 342
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9781483203713
- eBook ISBN: 9781483217147
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