Critical Care Medicine
Principles of Diagnosis and Management in the Adult
- 5th Edition - January 16, 2019
- Authors: Joseph E. Parrillo, R. Phillip Dellinger
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 4 4 6 7 6 - 1
Now completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, del… Read more
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Request a sales quoteNow completely revised to bring you up to date with the latest advances in the field, Critical Care Medicine: Principles of Diagnosis and Management in the Adult, 5th Edition, delivers expert, practical guidance on virtually any clinical scenario you may encounter in the ICU. Designed for intensivists, critical care and pulmonology residents, fellows, practicing physicians, and nurse practitioners, this highly regarded text is clinically focused and easy to reference. Led by Drs. Joseph Parrillo and Phillip Dellinger, the 5th Edition introduces numerous new authors who lend a fresh perspective and contribute their expertise to that of hundreds of top authorities in the field.
- Includes new chapters on current applications of bedside ultrasound in the ICU, both diagnostic and procedural; mechanical assist devices; and extra-corporeal membrane oxygenation (ECMO).
- Contains new administrative chapters that provide important information on performance improvement and quality, length of stay, operations, working with the Joint Commission, and more.
- Features new videos and images that provide visual guidance and clarify complex topics.
- Keeps you up to date with expanded chapters on echocardiography in the ICU and valvular heart disease, including TAVR.
- Includes separate chapters on mechanical ventilation of obstructive airway disease and acute respiratory distress syndrome (ARDS) – including the many recent changes in approach to positive end expiratory pressure setting in ARDS.
- Covers key topics such as patient-ventilator synchrony and non-invasive ventilation for treating chronic obstructive pulmonary disease patients with acute respiratory failure.
- Reflects the recent literature and guidance on amount of fluids, type of fluid, vasopressor selection, mean arterial pressure target, and decision on steroid use in septic shock.
- Provides questions and answers in every chapter, perfect for self-assessment and review.
- Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Critical care and pulmonology residents, fellows, practicing physicians, nurse practitioners (PA market very small)
- Cover image
- Title Page
- Table of Contents
- Copyright
- Dedication
- Preface
- Contributors
- Video Contents
- Chapter 8
- Chapter 14
- Chapter 18
- Chapter 38
- Part 1 Critical Care Procedures, Monitoring, and Pharmacology
- Introduction
- 1 Cardiac Arrest and Cardiopulmonary Resuscitation
- Abstract
- Epidemiology and General Principles
- Cardiopulmonary Resuscitation
- Advanced Cardiac Life Support
- Postresuscitation Care
- Key Points
- References
- Review Questions
- 2 Airway Management in the Critically Ill Adult
- Abstract
- Structure and Function of the Normal Airway
- Assessing Adequacy of the Airway
- Management of the Airway
- Physiologic Sequelae and Complications of Tracheal Intubation
- The Difficult Airway
- Confirming Tube Position in the Trachea
- Surgical Airway
- Extubation in the Difficult Airway Patient (Decannulation)
- Tube Displacement in the Critical Care Unit
- Human Factors
- Common Problems in Airway Management
- Key Points
- References
- Review Questions
- 3 Assessment of Cardiac Filling and Blood Flow
- Abstract
- Cardiac Filling
- Hemodynamic Status and Blood Flow
- Conclusions
- Key Points
- References
- Review Questions
- 4 Arterial, Central Venous, and Pulmonary Artery Catheters
- Abstract
- Arterial Catheters
- Central Venous Catheters
- Pulmonary Artery Catheters
- Key Points
- References
- Review Questions
- 5 Cardiac Pacing
- Abstract
- Electrocardiographic Considerations
- Clinical Evaluation of AV Block
- Management of Bradycardia and Indications of Temporary Pacing
- Cardiac Pacing Techniques
- Common Clinical Scenarios in Which Pacing Should Be Considered
- Conditions That Do Not Normally Require Pacing
- Permanent Pacing
- Indications for Permanent Pacemaker Implantation
- Complications of Permanent Pacemaker Implantation
- Special Considerations in Permanent Pacing
- Conclusions
- Key Points
- References
- Review Questions
- 6 Pericardial Tamponade
- Abstract
- Clinical Presentation
- Diagnosis
- Catheter-Based Therapies
- Pericardiocentesis
- Post-Pericardial Drain
- Percutaneous Balloon Pericardiotomy
- Surgical Drainage of Pericardium
- Key Points
- References
- Review Questions
- 7 Percutaneous Assist Devices
- Abstract
- Intraaortic Balloon Pump Counterpulsation
- Active Mechanical Circulatory Systems
- Impella Devices
- High-Risk Percutaneous Coronary Intervention
- Extracorporeal Membrane Oxygenation
- Key Points
- Acknowledgment
- References
- Review Questions
- 8 Echocardiography
- Abstract
- Approach to Echocardiography
- Echocardiographic Modalities
- Indications for Echocardiography
- Hemodynamic Assessment
- Stroke and Other Systemic Emboli
- Summary
- Key Points
- References
- Review Questions
- 9 General Principles of Mechanical Ventilation
- Abstract
- History
- Mechanical Ventilation
- Indications for Mechanical Ventilation
- Mechanical Breath Generation
- Ventilator Modes
- Other Modes of Mechanical Ventilation
- Positive End-Expiratory Pressure
- Monitoring the Ventilated Patient
- Maintaining Support of the Ventilated Patient
- Weaning From Mechanical Ventilation
- Complications of Mechanical Ventilation
- Noninvasive Positive-Pressure Ventilation
- Key Points
- References
- Review Questions
- 10 Ventilatory Management of Obstructive Airway Disease
- Abstract
- Special Challenges of Patients With Severe Airflow Obstruction
- Problems and Hazards of Ventilation With Positive Pressure
- Principles of Managing the Ventilated Patient With Severe Airflow Obstruction
- Practical Management of the Ventilated Patient
- PEEP and CPAP in Severe Airflow Obstruction
- Key Points
- References
- Review Questions
- 11 Mechanical Ventilation in Acute Respiratory Distress Syndrome
- Abstract
- History
- Physiologic Basis of Mechanical Ventilation
- Patient Characterization
- Respiratory Mechanics, Chest Wall Elastance, and Lung Volume
- Mechanical Ventilation in ARDS: Available Evidence
- Individualizing Mechanical Ventilation in Patients With ARDS
- Possible Adjuncts to Mechanical Ventilation
- Key Points
- References
- Review Questions
- 12 Bronchoscopy and Lung Biopsy in Critically Ill Patients
- Abstract
- Fiberoptic Brochoscopy-Induced Physiologic Changes
- Airway Evaluation and Management
- Diagnosis of Infection
- Lung Biopsy: Surgical, Transbronchial, and Cryobiopsy
- Special Situations
- Complications and Death
- Summary
- Key Points
- References
- Review Questions
- 13 Noninvasive Respiratory Monitoring
- Abstract
- Gas Exchange
- Respiratory Neuromuscular Function
- Respiratory Mechanics
- Key Points
- References
- Review Questions
- 14 Bedside Tracheostomy in the Intensive Care Unit
- Abstract
- Definition
- History
- Epidemiology
- Indications
- Contraindications (Box 14.2)
- Techniques
- Summary
- Key Points
- References
- Review Questions
- 15 Chest Tube Thoracostomy
- Abstract
- Historical Perspective
- Anatomy and Physiology of the Pleural Space
- Physiologic Changes With Pleural Effusions and Pneumothorax
- Indications for Tube Thoracostomy
- Contraindication to Tube Thoracostomy
- Drainage Systems
- Optimal Chest Tube Size for Drainage
- Technique of Chest Tube Insertion
- Management of the Chest Tube and Troubleshooting
- Complications
- Key Points
- References
- Review Questions
- 16 Multimodality Intracranial Monitoring
- Abstract
- Intracranial Pressure Monitoring
- Cerebral Blood Flow Monitoring
- Brain Tissue Oxygenation Monitoring
- Cerebral Microdialysis
- Summary
- Key Points
- References
- Review Questions
- 17 Gastrointestinal Endoscopy
- Abstract
- History
- Endoscopic Equipment
- Anesthesia
- Esophagogastroduodenoscopy
- Wireless Capsule Endoscopy
- Enteroscopy
- Colonoscopy
- Endoscopic Retrograde Cholangiopancreatography
- Endoscopic Ultrasound
- Endoscopy in the Pregnant Patient
- Key Points
- References
- Review Questions
- 18 Bedside Ultrasonography in the Critically Ill Patient
- Abstract
- Basic Ultrasound Terminology and Probe Characterization
- Basic Critical Care Echocardiography
- Performance of the CCE Examination
- The Basic CCE Examination
- Utility of Basic Critical Care Echocardiography
- Advanced Critical Care Echocardiography
- Thoracic Ultrasonography
- Clinical Applications of Thoracic Ultrasonography
- Abdominal Ultrasonography
- Ultrasonography for Guidance of Critical Care Procedures
- Quality Assurance and Imaging Archival Systems
- Conclusions
- Key Points
- References
- Review Questions
- 19 Continuous Renal Replacement Therapy
- Abstract
- Physiologic Principles
- Principles of Ultrafiltration
- CRRT Modalities
- Patient Selection and Timing of Initiation
- Discontinuation of CRRT
- Continuous RRT Versus Intermittent RRT
- Prescription Variables
- Technical Considerations
- Complications and Troubleshooting
- Multiorgan Support Technologies With CRRT
- Quality Assurance and Improvement for CRRT
- Key Points
- References
- Review Questions
- 20 Use of Sedatives, Analgesics, and Neuromuscular Blockers
- Abstract
- Considerations in Managing Sedation, Analgesia, and NMB in the ICU
- Pain Management in the Intensive Care Unit
- Sedation Management
- Neuromuscular Blocking Agents
- Summary and Conclusions
- Key Points
- References
- Review Questions
- 21 The Effect of Critical Illness on Pharmacokinetics and Pharmacodynamics
- Abstract
- Physiologic Changes in Critical Illness
- General Pharmacokinetic Principles
- Pharmacodynamics
- Dosing Considerations in Select Critical Care Patients
- Pharmacogenetics
- Principles of Therapeutic Drug Monitoring
- Conclusion
- Key Points
- Acknowledgment
- References
- Review Questions
- Part 2 Critical Care Cardiovascular Disease
- Introduction
- 22 Shock
- Abstract
- History
- Definitions and Categorization of Shock
- Classification
- Pathogenesis and Pathophysiology of Shock
- Organ System Dysfunction Owing to Shock (Table 22.3)
- Diagnostic Approach and Evaluation
- Management and Therapy
- Conclusion
- Key Points
- References
- Review Questions
- 23 Cardiogenic Shock
- Abstract
- Definition
- History
- Incidence
- Etiology and Epidemiology
- Pathogenesis
- Clinical Assessment and Initial Management
- Therapy
- Other Causes of Cardiogenic Shock
- Mechanical Support
- Conclusion
- Key Points
- References
- Review Questions
- 24 Severe Sepsis and Septic Shock
- Abstract
- Historical Perspective and Introduction
- Definitions
- Epidemiology
- Pathogenesis and Pathophysiology of Severe Sepsis and Septic Shock
- Clinical Presentation
- Cardiovascular Profile of Septic Shock
- Management of Severe Sepsis and Septic Shock
- Summary
- Appendix: Recommendations and Best Practice Statements
- References
- Review Questions
- 25 Cardiac Tamponade
- Abstract
- Fundamentals of Tamponade
- History and Physical Examination
- Diagnostic Tests
- Overall Assessment
- Special Syndromes in Tamponade
- Settings in Which Tamponade Is Seen
- Management
- Acknowledgment
- Key Points
- References
- Review Questions
- 26 Hypovolemia and Traumatic Shock
- Abstract
- Classic Neuroendocrine Response
- The Hypovolemic Patient
- Inflammation and Shock After Injury
- Blood Component Therapy
- Endpoints
- Clinical Strategies
- Management of Traumatic Shock in the ICU
- Special Problems
- Key Points
- References
- Review Questions
- 27 Severe Heart Failure
- Abstract
- Definition, Epidemiology, and Staging of Heart Failure
- Pathophysiology
- Diagnosis and Serum Natriuretic Peptides
- Acute Heart Failure Syndromes
- Pharmacologic Management of Acute Heart Failure
- Transition to Chronic Pharmacologic Therapy for Severe Heart Failure
- Acute Coronary Syndromes and Acute Heart Failure: Special Considerations
- Heart Failure With Preserved Left Ventricular Ejection Fraction (Diastolic Heart Failure)
- Myocarditis and Acute Heart Failure
- Device Therapy for Heart Failure and Ventricular Tachyarrhythmias: Implanted Cardioverter Defibrillator and Cardiac Resynchronization Therapy
- Severe Heart Failure and Mechanical Circulatory Support
- Key Points
- References
- Review Questions
- 28 Anaphylaxis and Anaphylactic Shock
- Abstract
- Pathophysiology
- Symptoms and Clinical Diagnosis
- Treatment and Management
- What Should Be Done After Recovery for Anaphylactic Shock?
- Key Points
- References
- Review Questions
- 29 Acute Coronary Syndromes and Acute Myocardial Infarction
- Abstract
- Definitions
- ST-Segment Elevation Myocardial Infarction
- Unstable Angina and Non–ST-Segment Elevation Myocardial Infarction
- Key Points
- References
- Review Questions
- 30 Valvular Heart Disease in Critical Care
- Abstract
- Aortic Stenosis
- Aortic Insufficiency
- Mixed Aortic Valve Disease
- Mitral Regurgitation
- Hypertrophic Obstructive Cardiomyopathy
- Mitral Valve Stenosis
- Prosthetic Heart Valves
- Key Points
- Acknowledgment
- References
- Review Questions
- 31 Cardiac Arrhythmias
- Abstract
- Bradycardias
- Supraventricular Tachycardia
- Management of SVT
- Ventricular Arrhythmias
- Metabolic Derangements
- Conclusions
- Key Points
- References
- Review Questions
- 32 Hypertensive Crises
- Abstract
- Introduction and Terminology
- Pathophysiology
- Approach to Management
- Specific Clinical Considerations
- Conclusions
- Key Points
- References
- Review Questions
- 33 Acute (Thoracic) Aortic Dissection
- Abstract
- History
- Types of Thoracic Aortic Dissection
- Risk Factors for Thoracic Aortic Dissection
- Pathophysiology
- Diagnosis
- Perioperative Management
- Operative Approach
- Outcomes and Prognosis
- Summary
- Key Points
- References
- Review Questions
- 34 General Principles of Postoperative Intensive Care Unit Care
- Abstract
- General Principles
- Best Practices: General Postoperative Care
- Surgical Complications
- Specific Surgical Specialty Operations
- Key Points
- References
- Review Questions
- 35 Postoperative Management of the Cardiac Surgery Patient
- Abstract
- Early Postoperative Care
- Common Postoperative Management Challenges
- Late Postoperative Care
- Cardiology
- Pulmonary
- Neurology
- Endocrine
- Renal
- Hematology
- Gastrointestinal
- Conclusion
- Key Points
- References
- Review Questions
- Part 3 Critical Care Pulmonary Disease
- Introduction
- 36 Acute Respiratory Failure
- Abstract
- Acute Respiratory Failure—Types 1 and 2
- Hypoxemic Respiratory Failure
- Hypercapnic Respiratory Failure
- Acute Respiratory Distress Syndrome
- Incidence and Prevalence
- Future Considerations
- Summary
- Key Points
- References
- Review Questions
- 37 Life-Threatening Asthma
- Abstract
- Epidemiology
- Genetics and Pathophysiology
- Signs and Symptoms
- Inhaled Therapies
- Systemic Therapies
- Mechanical Ventilation in Patients With Asthma
- The Future for Those With Life-Threatening Asthma
- Summary
- Key Points
- References
- Review Questions
- 38 Chronic Obstructive Pulmonary Disease
- Abstract
- Definitions
- Background
- Pathophysiology
- Clinical Manifestations
- Precipitating Factors
- Initial Management
- Noninvasive Mechanical Ventilation
- Invasive Mechanical Ventilation
- Terminal Care for the Patient With End-Stage COPD
- Key Points
- References
- Review Questions
- 39 Hypoventilation and Respiratory Muscle Dysfunction
- Abstract
- Decreased Neuromuscular Capacity
- Respiratory Muscle Weakness
- Increased Load
- Hypercapnia-Induced Hypoventilation
- Summary
- Key Points
- References
- Review Questions
- 40 Pneumonia
- Abstract
- Definitions
- Pathogenesis
- Community-Acquired (Community-Onset) Pneumonia
- Hospital-Acquired Pneumonia/Ventilator-Associated Pneumonia
- Key Points
- References
- Review Questions
- 41 Weaning from Mechanical Ventilation
- Abstract
- Pathophysiology of Weaning Failure
- Weaning-Predictor Testing
- Weaning Trials
- Conclusion
- Key Points
- References
- Review Questions
- 42 Acute Pulmonary Embolism
- Abstract
- Prevalence of Venous Thromboembolism in Intensive Care Unit Patients
- Risk Factors
- Deep Venous Thrombosis
- Pathophysiology
- Clinical Presentation
- Recognition of Pulmonary Embolism During Intensive Care Unit Admission
- Diagnostic Testing for Pulmonary Embolism
- Risk Stratification
- The Management of Acute Pulmonary Embolism
- Special Populations
- Prophylaxis
- Long-Term Prognosis
- Key Points
- Acknowledgment
- References
- Review Questions
- 43 Pulmonary Hypertension*
- Abstract
- Pathophysiology of PH and RV Failure
- Management of PH and RV Failure in the ICU
- Augmenting RV Cardiac Output
- Key Points
- References
- Review Questions
- 44 Massive Hemoptysis
- Abstract
- Anatomic Considerations
- Causes of Hemoptysis
- Invasive Pulmonary Interventions
- Management
- Key Points
- References
- Review Questions
- 45 Pneumothorax and Barotrauma
- Abstract
- Definition and History
- Incidence
- Pathophysiology
- Classification
- Clinical Features
- Electrocardiographic Features
- Diagnostic Imaging Modalities
- Differential Diagnosis: Conditions Mimicking Pneumothorax
- Management
- Complications Related to Management
- Key Points
- References
- Review Questions
- 46 Toxic Gas, Fume, and Smoke Inhalation
- Abstract
- Epidemiology
- Pathogenesis of Inhalation Injury
- Diagnostics and Treatment
- Key Points
- References
- Review Questions
- Part 4 Critical Care Infectious Disease
- Introduction
- 47 Nosocomial Infection in the Intensive Care Unit
- Abstract
- Incidence and Profile
- Morbidity and Economic Impact
- Pathogenesis and Epidemiology
- Pathogenesis and Epidemiology
- General Infection Control Measures
- Nosocomial Infections and Specific Infection Control Measures
- Avant Garde Infection Control Measures
- Approach to a Nosocomial Epidemic
- Approach to a Nosocomial Epidemic
- Protection of Health Care Workers in the Intensive Care Unit
- Goals for the Future
- Key Points
- References
- Review Questions
- 48 Principles Governing Antimicrobial Therapy in the Intensive Care Unit
- Abstract
- Right Drug
- Right Time
- Right Dose
- Right Duration
- Antibiotic Stewardship in the Intensive Care Unit
- Conclusions
- Key Points
- References
- Review Questions
- 49 Antifungal and Antiviral Therapy
- Abstract
- Systemic Antifungal Agents
- Specific Indications and Uses for Antifungals
- Candida Infections
- Areas of Controversy in Antifungal Therapy
- Antiviral Agents
- Specific Indications and Uses for Antivirals
- Key Points
- References
- Review Questions
- 50 Critically Ill Immunosuppressed Host
- Abstract
- Definition
- Overview of Immune and Inflammatory Responses
- General Approach to Management of Patients With Altered Immune and Inflammatory Responses
- Management of Specific Patient Populations
- Key Points
- References
- Review Questions
- 51 Specific Infections With Critical Care Implications
- Abstract
- Overwhelming Infections of the Central Nervous System
- Fulminant Endovascular Infections
- Primary Bacteremias
- Toxin-Mediated Infections
- Serious Skin and Soft Tissue Infections
- Serious Gastrointestinal and Intra-abdominal Infections
- Life-Threatening Infections of the Head and Neck
- Serious Vector-Borne Infections
- Severe Viral Infections
- Potential Agents of Bioterrorism
- Key Points
- References
- Review Questions
- Part 5 Renal Disease and Metabolic Disorders in the Critically Ill
- Introduction
- 52 Acute Kidney Injury
- Abstract
- Definition
- Pathogenesis
- Clinical Manifestations
- Diagnostic Approach
- Prevention
- Management of Established Acute Kidney Injury
- Prognosis and Outcomes
- Key Points
- References
- Review Questions
- 53 Chronic Kidney Disease
- Abstract
- Introduction
- Physiology of Chronic Kidney Disease
- End-Stage Renal Disease
- Kidney Transplantation
- Drug Dosing
- Summary
- Key Points
- References
- Review Questions
- 54 Acid-Base, Electrolyte, and Metabolic Abnormalities
- Abstract
- Metabolic Disorders of Acid-Base Homeostasis
- Disorders of Potassium Homeostasis
- Disorders of Water Homeostasis
- Calcium
- Disorders of Magnesium Homeostasis
- Phosphorus
- Key Points
- References
- Review Questions
- 55 Acute Diabetic Emergencies, Glycemic Control, and Hypoglycemia
- Abstract
- Diabetes Mellitus: Epidemiology and Classification
- Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State
- Glycemic Control in the ICU
- The Effect of Parenteral Nutrition, Enteral Nutrition, and Glucocorticoids on Glycemic Control
- Hypoglycemia
- Key Points
- References
- Review Questions
- 56 Adrenal Insufficiency in the Critically Ill Patient
- Abstract
- Incidence and Prevalence
- Etiology and Pathogenesis
- Clinical Features
- Diagnosis
- Critical Illness–Related Corticosteroid Insufficiency
- Management
- Etomidate
- Summary
- Key Points
- References
- Review Questions
- 57 Thyroid Disorders
- Abstract
- Thyroid Physiology
- Thyroid Function Tests
- Drug Effects and Thyroid Function
- Nonthyroidal Illness Syndrome
- Hypothyroidism and Myxedema Coma
- Thyrotoxicosis and Thyroid Storm
- Key Points
- References
- Review Questions
- Part 6 Neurologic Disease in the Critically Ill
- Introduction
- 58 Coma
- Abstract
- Consciousness and Its Clinical Spectrum
- Neurobiology of Consciousness
- Assessment and Acute Management of Coma
- Assigning a Neurologic Profile
- Electrophysiology
- Initiating Target Treatments Based on Etiology of Coma
- Ethical Considerations
- Key Points
- References
- Review Questions
- 59 Neurologic Criteria for Death in Adults
- Abstract
- Historical Perspective and Definitions
- Determination of Brain Death
- Confirmatory Testing
- Special Circumstances
- Conclusions
- Key Points
- References
- Review Questions
- 60 Stroke
- Abstract
- Historical Background
- Overview
- Advances in Radiology
- Thrombolysis in Stroke
- Endovascular Mechanical Thrombectomy
- Symptomatic Carotid Disease/Stenting
- Anticoagulation in Stroke
- Antiplatelet Agents in Stroke
- Patent Foramen Ovale
- Prolonged Cardiac Monitoring
- Massive Hemispheric Cerebral Infarct
- Critical Care Consultation
- Summary
- Key Points
- References
- Review Questions
- 61 Myasthenia Gravis and Guillain-Barré Syndrome
- Abstract
- Guillain-Barré Syndrome
- Myasthenia Gravis
- Complications
- Key Points
- References
- Review Questions
- 62 Seizures in the Critically Ill
- Abstract
- History
- Epidemiology
- Nosology and Semiology
- Pathogenesis
- Pathophysiology
- Clinical Manifestations
- Diagnostic Approach
- Management Approach
- Prognosis
- Key Points
- References
- Review Questions
- 63 Head Injury
- Abstract
- Incidence
- Diagnostic Approach
- Primary Head Injury
- Secondary Head Injury
- Specific Treatment Considerations
- Conclusions
- Key Points
- References
- Review Questions
- Part 7 Physical and Toxic Injury in the Critically Ill Patient
- Introduction
- 64 Critical Care of the Severely Burned
- Abstract
- Introduction
- Epidemiology
- Phases of Burn Care
- Initial Assessment and Triage (Phase I)
- Primary Survey
- Fluid Resuscitation: The First 48 Hours (Phase II)
- Optimizing Burn Wound Coverage (Phase III)
- Critical Care (Phase III Continued)
- Rehabilitation (Phase IV)
- Key Points
- References
- Review Questions
- 65 Poisonings
- Abstract
- Resuscitation and Stabilization
- Diagnosis
- Gastrointestinal Decontamination
- Enhanced Elimination
- Specific Poisonings
- Key Points
- References
- Review Questions
- 66 Hypothermia, Hyperthermia, and Rhabdomyolysis
- Abstract
- Hypothermia
- Hyperthermia
- Malignant Hyperthermia
- Neuroleptic Malignant Syndrome
- Rhabdomyolysis
- Key Points
- References
- Review Questions
- Part 8 Administrative, Ethical, and Psychological Issues in the Care of the Critically Ill
- Introduction
- 67 Performance Improvement and Severity Scores in Critical Care
- Abstract
- Critical Care Performance Improvement
- Culture Transformation and Organizational Learning
- Critical Care Scoring Systems
- Summary and Conclusions
- Key Points
- References
- Review Questions
- 68 Ethical Considerations in Managing Critically Ill Patients
- Abstract
- Informed Consent and Decision Making in Critical Care
- Practical Aspects of Withdrawing Life-Sustaining Treatments in the ICU
- Key Points
- References
- Review Questions
- 69 Delirium, Sleep, and Mental Health Disturbances in Critical Illness
- Abstract
- Overview
- Acute Brain Dysfunction or Delirium
- Sleep Disruption in the Critically Ill
- Posttraumatic Stress Disorder
- Long-Term Cognitive Impairment After Critical Illness
- Depression
- Concluding Thoughts
- Key Points
- References
- Review Questions
- 70 Intensive Care Unit Administration and Education
- Abstract
- ICU Administration
- Education in Critical Care: An Administrator's Perspective
- Summary
- References
- Review Questions
- Part 9 Other Critical Care Disorders and Issues in the Critically Ill
- Introduction
- 71 Diagnosis and Management of Liver Failure in the Adult
- Abstract
- Decompensation of Chronic Liver Disease
- Acute (Fulminant) Liver Failure
- Key Points
- References
- Review Questions
- 72 Gastrointestinal Bleeding
- Abstract
- Clinical Presentation
- Upper Gastrointestinal Bleeding
- Stress-Related Mucosal Disease
- Lower Gastrointestinal Bleeding
- Obscure Gastrointestinal Bleeding
- Conclusion
- Key Points
- References
- Review Questions
- 73 Acute Pancreatitis
- Abstract
- Definitions and Terminology
- Pathogenesis
- Etiology and Risk Factors
- Clinical Presentation and Diagnosis
- Early Management of the Critically Ill Patient With Acute Pancreatitis
- Management of the Late Complications of Severe Acute Pancreatitis
- Long-Term Outcome and Quality of Life
- Conclusions
- Key Points
- References
- Review Questions
- 74 Hemorrhagic and Thrombotic Disorders
- Abstract
- Approach to a Critically Ill Patient With Hemorrhage or Thrombosis
- Laboratory Tests of Coagulation
- Disorders of Platelets
- Complex Thrombohemorrhagic Disorders
- Catastrophic Antiphospholipid Syndrome
- Disorders of Hemostasis
- Venous Thromboembolism
- Anticoagulants
- Key Points
- References
- Review Questions/Answers
- 75 Use of Blood Components in the Intensive Care Unit
- Abstract
- Blood Components and Indications for Transfusion
- Adverse Effects of Blood Component Transfusion
- Special Transfusion Situations in the Critical Care Setting
- Alternatives to Transfusion of Blood Components
- Legal Issues in Transfusion Medicine
- Key Points
- References
- Review Questions
- 76 Intensive Care of the Cancer Patient
- Abstract
- Reasons for ICU Admission
- Triage of Cancer Patients for ICU Care
- Palliative, Ethics, and End-of-Life Care Issues
- Summary
- Key Points
- References
- Review Questions
- 77 Critical Care Medicine in Pregnancy
- Abstract
- Physiologic Changes in Pregnancy
- Critical Care Management
- Ventilatory Support
- Pregnancy-Specific Conditions Requiring ICU Care
- Conditions Not Specific to Pregnancy
- Key Points
- References
- Review Questions
- 78 Nutrition Support
- Abstract
- Malnutrition
- Starvation Versus Stress Metabolism
- Indications for Nutrition Support
- Goals of Nutrition Support
- Nutrition Support in Critical Illness
- Route and Timing of Administration
- Types of Nutritional Formulas
- Nutritional Assessment and Monitoring
- Key Points
- References
- Review Questions
- Index
- No. of pages: 1346
- Language: English
- Edition: 5
- Published: January 16, 2019
- Imprint: Elsevier
- Hardback ISBN: 9780323446761
JP
Joseph E. Parrillo
Affiliations and expertise
Chairman, Heart and Vascular Hospital, Hackensack University Medical Center; Professor of Medicine, Rutgers New Jersey Medical School, Hackensack, New JerseyRD
R. Phillip Dellinger
Affiliations and expertise
Professor of Medicine, Cooper Medical School of Rowan University; Director, Critical Care, Cooper University Hospital, Camden, NJ