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CRISPR-Cas System in Translational Biotechnology

  • 1st Edition - November 16, 2023
  • Latest edition
  • Editors: Swati Joshi, Digvijay Verma, Ravi Kr. Gupta
  • Language: English

CRISPR-Cas System in Translational Biotechnology discusses applied and translational aspects of the CRISPR-Cas technology. The book bridges the gap between theoretical knowledge… Read more

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Description

CRISPR-Cas System in Translational Biotechnology discusses applied and translational aspects of the CRISPR-Cas technology. The book bridges the gap between theoretical knowledge and practical solutions surrounding this emerging and impactful technology in several academic and industrial fields. It is split in five sections: CRISP-Cas fundamentals and advancements; CRISP-Cas in medical biotechnology; CRISP-Cas in environmental biotechnology; CRISP-Cas in food biotechnology; and biosafety, patents and commercialization of CRISP-Cas technology. Written by experts from diverse backgrounds, the content covers the subject and its impact in multiple fields.

It is a valuable resource for graduate students and researchers on bioinformatics, systems biology, and members of the biomedical field and biotechnology industry who are interested in learning more about CRISP-Cas system and its applications.

Key features

  • Discusses applied aspects of CRISPR-Cas technology and state-of-the-art technological/translational advancements in the field
  • Focuses on the CRISPR-Cas mediated genetic engineering for employment in various industries such as medical, agricultural, environmental and food
  • Encompasses knowledge on CRISPR-Cas commercialization, potential markets and associated ethical challenges

Readership

Graduate students and researchers on systems biology and bioinformatics, biotechnology industry sector, Graduate students and researchers on cancer research and diverse fields of medicine, agriculture, and environmental sciences

Table of contents

Part I. CRISPR/Cas Fundamentals and advancements 1. CRISPR-Cas Fundamentals and Advances (In Translational Biotechnology) 2. An overview of the CRISPR-Cas System: Applications and Opportunities 3. CRISPR-Cas 9: A solution to rapid befalling global epidemic of bacterial antimicrobial resistance 4. CRISPR-Cas9 and comparison with other gene editing tools Part II. CRISPR/Cas in Medical Biotechnology 5. Molecular engineering of CRISPR-Cas system toward in-vitro diagnostics 6. Genome editing with CRISPR-Cas: The future of infectious disease 7. Role of CRISPR in cancer research and treatment 8. Genome engineering with CRISPR-Cas: Revolutionizing healthcare 9. Role of CRISPR-Cas in cancer treatments 10. Unlocking new ways to tackle tuberculosis using CRIPSR-Cas as potent weapon 11. Translational biotechnology and CRISPR-Cas Part III. CRISPR/Cas in Environmental Biotechnology 12. Dealing environmental problems using CRISPR-Cas tools 13. Translational and evolutionary effect of CRISPR-Cas system in environmental sustainability 14. Employment of CRISPR/Cas on microorganisms for improving the fertility of the soil Part IV. CRISPR/Cas in Food Biotechnology 15. Modifying food bacteria using CRISPR-Cas technology 16. CRISPR-Cas technologies in food security and food revolution 17. CRISPR technology: A revolutionizing tool for crop improvement 18. Biotechnological applications of CRISPR-Cas systems in fungi Part V. Biosafety, patents, and commercialization of CRISPR-Cas technology 19. Commercial application of CRISPR technology in gene therapy 20. Application of CRISPR-Cas in disease diagnosis and management 21. CRISPR: The Janus God of modern science 22. Commercialization and allied aspects of CRISPR techniques

Product details

  • Edition: 1
  • Latest edition
  • Published: November 16, 2023
  • Language: English

About the editors

SJ

Swati Joshi

Swati Joshi is currently a Scientist at the ICMR-National Institute of Occupational Health (NIOH) in Ahmedabad, India. She previously served as Assistant Professor and BioCARe Women Scientist in the School of Life Sciences at Central University of Gujarat (CUG). Dr. Joshi earned a PhD in Microbiology from the University of Delhi, working at the interface of microbiology, biotechnology and molecular biology using next gen platforms to develop industrial strains of methylotrophic Pichia sp. Her research focuses on applied microbiology, biotechnology, microbial enzymes, proteins, phage discovery, and microbe-derived molecules for therapeutic and diagnostic applications especially for occupational health. She has published over 27 peer-reviewed papers, reviews, book chapters, and edited two Elsevier books. Dr. Joshi is a life member of BRSI, MSI, AMI, and ILS and has been recognized with the Dr. M. J. Thirumalachar Young Scientist Award (Mycological Society of India) and Young Scientist Award (Association of Microbiologists of India).

Affiliations and expertise
Scientist, Division of Biological Sciences ICMR-National Institute of Occupational Health (NIOH) Ahmedabad, Gujarat, India

DV

Digvijay Verma

Digvijay Verma has been working in the field of genomics and metagenomics for the last 10 years. He has expertise in heterologous expression of genes from extreme environments into the various Gram-negative and Gram-positive bacterial hosts. His research work on proteins reflects his extensive understanding of industrial biotechnology and extremophilic microorganisms. His laboratory is engaged in exploiting therapeutic bioactive molecules from extreme habitats using metagenomic approaches. He is also in a phase of developing pipelines for robust microbiome analysis. Dr. Verma has also been working on analyzing the oral microbiome from the Indian community and the influence of external risk factors on the overall oral bacterial composition. He is a life member of many scientific organizations like the Association of Microbiologists of India (AMI), Biotech Research Society of India (BRSI), and Indian Science Congress (ISC). He is coauthor of Microorganisms for Sustainable Environment and Health (Elsevier, 2020).
Affiliations and expertise
Department of Environmental Microbiology, School of Earth and Environmental Sciences, Babasaheb Bhimrao Ambedkar University, India

RG

Ravi Kr. Gupta

Ravi Kr. Gupta was awarded with several national level scholarships from CSIR and ICMR during his doctoral study and his PhD thesis was awarded Dr. M. M. Dhar Award. Then he moved to the USA as a postdoctoral fellow to enhance his research skills with the state-of-the art techniques in genes and small non-coding RNA regulation in bacteria. Currently he works as assistant professor of microbiology at Babasaheb Bhimrao Ambedkar University (A Central University). His long-term research goals are to better understand the regulatory mechanism of small non-coding RNAs and their role in human and animal pathogens that may lead to the development of alternative therapeutic approach to treat infections. His laboratory is also working to identify novel antimicrobials from natural sources against gram-positive and gram-negative pathogens.
Affiliations and expertise
Assistant Professor, Department of Environmental Microbiology, School of Earth and Environmental Sciences, Babasaheb Bhimrao Ambedkar University, India

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