Crash Course Haematology and Immunology
For the MLA and Medical Exams
- 6th Edition - December 27, 2024
- Imprint: Elsevier
- Authors: Priya Sriskandarajah, Ioanna Lazana, Maheen Ahsan, Michael Lim
- Editors: Philip Xiu, Varun Mehra
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 4 9 9 6 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 5 0 3 5 - 4
Crash Course – your effective every-day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have the essential information you need in one pla… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteCrash Course – your effective every-day study companion PLUS the perfect antidote for exam stress! Save time and be assured you have the essential information you need in one place to excel on your course and achieve exam success.
A winning formula now for over 25 years, having sold over 1 million copies and translated in over 8 languages, each series volume has been fine-tuned and fully updated to make your life easier. Especially written by senior students or junior doctors/residents – those who understand what is essential for exam success – with all information thoroughly checked and quality assured by expert Faculty Advisers, the result is books that exactly meet your needs and you know you can trust.
Each chapter guides you succinctly through the full range of curriculum topics in the MLA syllabus, integrating clinical considerations with the relevant basic science and avoiding unnecessary or confusing detail. Text boxes help you get to the hints, tips and key points you need fast! A fully revised self-assessment section matching the latest exam formats is included to check your understanding and aid exam preparation. The accompanying enhanced, downloadable eBook completes this invaluable learning package.
Series volumes have been honed to meet the requirements of today’s medical students, although the range of other health students and professionals who need rapid access to the essentials of haematology and immunology will also love the unique approach of Crash Course. Whether you need to get out of a fix or aim for a distinction Crash Course is for you!
This updated edition features brand new high-resolution colour images of commonly tested blood films, vivid photographs of haematological skin manifestations, and revamped immunology sections. All new OSCE cases as well as MLA style questions, it covers cutting-edge immunological advancements including mRNA vaccines, biologics, and CAR-T therapy, providing an essential visual and theoretical resource for students.
- Fully aligned to MLA requirements, with key ‘conditions’ and ‘presentations’ highlighted in handy checklists - save valuable revision time and be confident you have the syllabus covered
- Updated self-assessment section matching the latest exam formats – confirm your understanding and improve exam technique fast
Medical students, junior doctors
- Cover image
- Edition Author
- Title page
- Copyright
- Series editor’s foreword
- Preface
- Acknowledgements
- Series editor’s acknowledgement
- Rapid MLA Index
- Table of Contents
- 1 Principles of haematology
- Principles
- Blood
- Blood cells
- Haematopoiesis
- Bone marrow
- The spleen
- Lymphadenopathy
- 2 Red blood cells and haemoglobin
- Erythrocytes
- Erythropoiesis
- Haemoglobin
- Myoglobin
- Iron and haem metabolism
- Haemoglobin metabolism
- Red cell cytoskeleton
- Red cell metabolism
- Methaemoglobinaemia
- Full blood count and reticulocyte count
- Peripheral blood film
- 3 Red blood cell disorders
- Anaemia
- Anaemia secondary to haematinic deficiency
- Anaemia of chronic disease
- Anaemia due to blood loss
- Microcytic anaemia: other causes
- Haemolytic anaemia
- Antibody-mediated haemolysis
- Intrinsic red cell defects causing haemolysis
- Other causes of haemolysis
- Haemoglobinopathies
- Electrophoresis: investigation of haemoglobinopathies
- Marrow defects causing anaemia
- Polycythaemia
- 4 White blood cells
- Leucocyte structure
- Leucocyte differentiation
- Left and right shift
- White count differential
- Leucocytosis
- Leucopoenia
- 5 Haematological malignancies
- Introduction
- Myeloproliferative neoplasms
- Myelodysplastic syndromes
- Leukaemias
- Acute leukaemias
- Chronic leukaemias
- Malignant lymphomas
- Age-specific haematological malignancy risk
- Plasma cell dyscrasias
- Investigations in haematological malignancy
- Chemotherapy and targeted treatments
- 6 Haemostasis
- Introduction
- Platelets
- Antiplatelet drugs
- Platelet disorders
- The coagulation cascade
- Traditional pathways
- Currently accepted pathway
- Regulation of coagulation
- Fibrinolysis
- Overview of haemostasis
- Coagulation assays
- Clotting factor disorders
- Hereditary factor deficiencies
- Thrombosis
- Secondary (acquired) thrombophilias
- Primary (hereditary) thrombophilias
- Venous thromboembolism
- Anticoagulation
- Thromboprophylaxis
- Therapeutic thrombolysis
- 7 Blood transfusion
- Introduction
- Red cell antigens
- The ABO blood group system
- Rh blood group system
- Other red cell antigens
- Red cell transfusions
- Alternatives to red cell transfusions
- Other transfusion products
- Transfusion reactions
- Major haemorrhage
- 8 Principles of immunology
- An introduction to immunology
- 9 The innate immune system
- Barriers to infection
- Cells of innate immunity
- Soluble proteins
- Innate immune system pattern recognition molecules
- References
- 10 The adaptive immune system
- The immunoglobulin domain
- Generation of antigen receptor diversity
- Humoral immunity
- Cell-mediated immunity
- Tolerance
- 11 The functioning immune system
- Response to tissue damage
- Immune response to pathogens
- 12 Immune dysfunction
- Hypersensitivity
- Type I hypersensitivity (immediate hypersensitivity)
- Type II hypersensitivity
- Type III hypersensitivity (immune complex)
- Type IV hypersensitivity (delayed-type hypersensitivity)
- Immune system disorders (instead of ‘development of hypersensitivity’)
- Examples of autoimmune diseases
- Immune deficiency
- Investigation of a patient with possible immune deficiency
- References
- 13 Medical intervention
- Immunization
- Transplantation
- Medications used for the prevention of immune rejection
- Cancer immunotherapy
- Self-Assessment
- MLA High Yield Association Table
- MLA Single Best Answer (SBA) Questions
- MLA SBA Answers
- Short Cases
- Glossary
- Index
- Edition: 6
- Published: December 27, 2024
- Imprint: Elsevier
- No. of pages: 223
- Language: English
- Paperback ISBN: 9780443249969
- eBook ISBN: 9780443250354
PS
Priya Sriskandarajah
Affiliations and expertise
Consultant Haematologist, Guy’s Hospital London, UKIL
Ioanna Lazana
Affiliations and expertise
Consultant Haematologist, King’s College Hospital London, UKMA
Maheen Ahsan
Affiliations and expertise
Internal Medicine Trainee, King’s College Hospital London, UKML
Michael Lim
Affiliations and expertise
Haematology Registrar, Guy’s Hospital London, UK