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Conn's Current Therapy 2023
- 1st Edition - November 2, 2022
- Editors: Rick D. Kellerman, David P. Rakel
- Language: English
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 0 5 6 2 - 3
Trusted by clinicians for more than 75 years, Conn’s Current Therapy presents today’s evidence-based information along with the personal experience and discernment of expert… Read more
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Request a sales quoteTrusted by clinicians for more than 75 years, Conn’s Current Therapy presents today’s evidence-based information along with the personal experience and discernment of expert physicians. The 2023 edition is an excellent resource for a wide range of healthcare professionals, including primary care, subspecialists, and allied health, providing current treatment information in a concise yet in-depth format. Nearly 350 topics have been carefully reviewed and updated to bring you state-of-the-art content in even the most rapidly changing areas of medicine.
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Offers personal approaches from recognized leaders in the field, covering common complaints, acute diseases, and chronic illnesses along with the most current evidence-based clinical management options.
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Follows a consistent, easy-to-use format throughout, with diagnosis, therapy, drug protocols, and treatment pearls presented in quick-reference boxes and tables for point-of-care answers to common clinical questions.
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Includes new chapters on leg edema and venous stasis, multisystem inflammatory syndrome in children (MIS-C), monoclonal antibodies, and genetic testing.
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Incorporates more electronic links throughout the text that connect the reader to apps and clinical prediction tools that can easily be accessed in practice.
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Features thoroughly reviewed and updated information from many new authors and two new associate editors, Drs. Joel J. Heidelbaugh and Ernestine M. Lee, who offer a fresh perspective and their unique personal experience and judgment.
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Provides current drug information thoroughly reviewed by PharmDs.
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Features nearly 300 images, including algorithms, anatomical illustrations, and photographs, that provide useful information for diagnosis.
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Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Family medicine
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Preface
- Body Mass Index
- Section I. Symptomatic Care Pending Diagnosis
- Chest Pain
- Epidemiology
- Initial Assessment
- Diagnosis and Treatment
- Constipation
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Treatment
- Complications
- Cough
- Acute Cough
- Chronic Cough
- Dizziness and Vertigo
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Complications
- Fatigue
- Epidemiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- Fever
- Definitions
- Pathophysiology
- Risks and Benefits of Fever
- Diagnostic Evaluation of Fever
- Differential Diagnosis
- Treatment
- Gaseousness, Indigestion, Nausea, and Vomiting
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Complications
- Hematuria
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy, Monitoring, and Complications
- Hiccups
- Mechanistic Description
- Classifications
- Epidemiology
- Pathophysiology
- Evaluation of the Hiccup Patient
- Nonpharmacologic Interventions
- Pharmacologic Interventions
- Physical Interventions
- Treatment
- Hoarseness and Laryngitis
- Normal Laryngeal Function
- Evaluation of Dysphonia
- Types of Dysphonia
- Neurologic Disorders and the Voice
- Functional Voice Disorders
- Presbylaryngis
- Conclusion
- Leg Edema And Venous Stasis
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy (or Treatment)
- Monitoring
- Complications
- Pain
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Palliative and End-of-Life Care
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Pain
- Dyspnea
- Nausea/Vomiting
- Constipation
- Anxiety
- Delirium
- Hiccups
- Monitoring
- Palliative Sedation
- Physician-Assisted Suicide
- Complications
- Palpitations
- Epidemiology
- Differential Diagnosis
- Risk Factors
- Pathophysiology
- Clinical Assessment
- Diagnostic Testing
- Treatment
- Pharyngitis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Pruritus
- Classification
- Pathophysiology
- Clinical Manifestations
- Differential Diagnosis
- Therapy
- Complications
- Rhinitis
- Introduction
- Epidemiology/Risk Factors
- Pathophysiology
- Clinical History
- Physical Examination
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Spine Pain
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Complications
- Tinnitus
- Definition and Epidemiology
- Risk Factors and Etiologies
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- History
- Examination
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Section II. Allergy
- Allergic Reactions to Insect Stings
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy and Monitoring
- Anaphylaxis
- Introduction
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Management of Complications
- COVID-19 Vaccines and Anaphylaxis
- Conclusion
- Drug Hypersensitivity Reactions
- Epidemiology
- Classifications
- Pathophysiology
- Risk Factors for Hypersensitivity Drug Reactions
- Clinical Manifestations
- Evaluation
- Management
- Specific Drugs
- Antibiotics
- Penicillin and Cephalosporin Cross-Reactivity
- Sulfonamides (Sulfa Drugs)
- Angiotensin-Converting Enzyme Inhibitors
- Aspirin and NSAIDs
- Radiocontrast Media
- Chlorhexidine
- Herbal Supplements
- Conclusion
- Serum Sickness
- Pathophysiology
- Epidemiology
- Risk Factors
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Section III. Cardiovascular System
- Acute Myocardial Infarction
- Diagnosis
- Management of STEMI
- Adjunct Therapy
- Complications of STEMI
- Angina Pectoris
- Clinical Features
- Diagnostic Testing
- Risk Factor Management
- Approach to Treatment
- Medication Combinations
- Antiplatelet Therapy
- Other Causes of Angina
- Newer Imaging Techniques
- Summary
- Aortic Disease: Aneurysm and Dissection
- Abdominal Aortic Aneurysms
- Diagnosis
- Treatment
- Thoracic Aortic Aneurysms
- Thoracoabdominal Aortic Aneurysms
- Thoracic Aortic Dissection
- Atrial Fibrillation
- Epidemiology
- Risk Factors and Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Special Considerations
- Congenital Heart Disease
- Acyanotic Conditions
- Cyanotic Conditions
- Congestive Heart Failure
- Heart Failure Definition
- Epidemiology
- Heart Failure Classification Based on Left Ventricular Ejection Fraction (LVEF)
- Functional Capacity
- Left Ventricular Physiology and Hemodynamic Profile
- Neurohormone and Sympathetic Nervous System Activation
- Diagnosis
- Laboratory and Diagnostic Tests
- Therapy for HFrEF
- Renin-Angiotensin-Aldosterone System Inhibitors
- Aldosterone Antagonists
- Sympathetic Nervous System
- Hydralazine and Isosorbide Dinitrate Combination
- Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2 Inhibitors)
- Ivabradine
- Digoxin
- Device Therapies
- Therapy for HFpEF
- Advanced Heart Failure
- Heart Block
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Complications
- Conclusions
- Hypertension
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment Approaches
- Monitoring
- Complications
- Hypertrophic Cardiomyopathy
- Definition
- Epidemiology
- Risk Factors
- Clinical Manifestations
- Pathogenesis
- Diagnosis
- Imaging
- Treatment
- Symptomatic Disease
- Participation in Sports
- Monitoring
- Future Research
- Infective Endocarditis
- Definition
- Epidemiology and Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations and Diagnosis
- Differential Diagnosis
- Laboratory Evaluation and Blood Cultures
- Imaging
- Treatment
- Complications and Surgical Indications
- Conclusion
- Mitral Valve Prolapse
- Prevalence
- Classification
- Pathology
- Clinical Presentation
- Diagnosis
- Use of Echocardiography
- Medical Management
- Surgical Management
- Percutaneous Management
- Pericarditis
- Anatomy and Functions of the Pericardium
- Acute Pericarditis
- Etiology
- Presentation
- Diagnostic Evaluation
- Clinical Laboratory Data
- ECG
- Imaging
- Treatment
- Constrictive Pericarditis
- Peripheral Artery Disease
- Epidemiology and Risk Factors
- Pathophysiology
- Prevention and Screening Recommendations
- Clinical Manifestations
- Physical Examination
- Diagnosis
- Ankle-Brachial Index
- Differential Diagnosis
- Treatment
- Monitoring
- Premature Beats
- Premature Atrial Contractions
- Premature Ventricular Contractions
- Premature Junctional Contractions
- Tachycardias
- Definition
- Classification
- Epidemiology
- Pathophysiology
- Clinical Presentation
- Diagnosis
- Differential Diagnosis for Narrow Complex Tachycardias
- Differential Diagnosis for Wide Complex Tachycardias
- Specific Tachycardias and Their Treatment
- Valvular Heart Disease
- Aortic Stenosis
- Etiology
- Pathophysiology
- Clinical Presentation
- Diagnosis and Management
- Treatment
- Invasive Treatment
- Mitral Regurgitation
- Venous Thrombosis
- Epidemiology
- Risk Factors
- Pathophysiology
- Diagnosis
- Treatment
- Nonpharmacologic Treatments
- Section IV. Digestive System
- Acute and Chronic Pancreatitis
- Acute Pancreatitis
- Chronic Pancreatitis
- Treatment
- Acute Diarrhea
- Epidemiology
- Etiology and Treatment
- Traveler’s Diarrhea
- Treatment
- Bleeding Esophageal Varices
- Epidemiology
- Pathophysiology
- Diagnosis
- Treatment
- Summary
- Calculous Biliary Disease
- Cholelithiasis
- Choledocholithiasis
- Acute Cholecystitis
- Gangrenous Cholecystitis, Emphysematous Cholecystitis, and Gallbladder Perforation
- Gallbladder Disease in Pregnancy
- Chronic Diarrhea
- Epidemiology
- Classification Based on Etiology
- Testing for Diagnosis
- Treatment
- Cirrhosis
- Epidemiology
- Clinical Findings
- Natural History of Cirrhosis and Prognostic Models
- Major Complications of Cirrhosis
- Liver Transplantation
- Diverticula of the Alimentary Tract
- Esophagus
- Stomach
- Small Intestine
- Colon
- Dysphagia and Esophageal Obstruction
- Epidemiology
- Pathophysiology
- Diagnosis
- Diagnostic Testing
- Oropharyngeal Dysphagia
- Management
- Esophageal Dysphagia
- Differential Diagnosis: Mechanical Obstruction (Table 2)
- Management for Esophageal Obstruction
- Differential Diagnosis: Motility Disorders (Table 3)
- Monitoring
- Acknowledgment
- Gastritis and Peptic Ulcer Disease
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Gastroesophageal Reflux Disease (GERD)
- Pathophysiology
- Complications
- Diagnosis
- Management
- Hemorrhoids, Anal Fissure, and Anorectal Abscess And Fistula
- History
- Diagnosis
- Hemorrhoids
- Anal Fissure
- Anorectal Abscess and Fistula
- Hepatitis A, B, D, and E
- Hepatitis A Virus
- Hepatitis E
- Hepatitis B
- Hepatitis D
- Hepatitis C
- Virology, Pathogenesis, and Natural History
- Epidemiology
- Risk Factors
- Diagnosis
- Prevention
- Therapy
- Monitoring
- Inflammatory Bowel Disease
- Introduction and Epidemiology
- Clinical Features
- Natural History
- Diagnosis
- Imaging
- Endoscopy and Histology
- Extraintestinal Manifestations
- Management of Disease
- Medical Therapy
- Cytokine Inhibitors
- Immunomodulators
- Small Molecules
- Preventive Care in Inflammatory Bowel Disease
- Conclusion
- Intestinal Parasites
- Protozoa: Amoebae, Flagellates, and Ciliates
- Spore-Forming Protozoa and Microsporidia
- Helminths
- Irritable Bowel Syndrome
- Introduction and Definitions
- Epidemiology
- Causality: A Biopsychosocial Model of Functional Gastrointestinal Disorders Such as IBS
- Impact on Population Health
- Direct Healthcare Costs
- Evaluation of Patients with Suspected Irritable Bowel Syndrome
- Tests of Unproven Value
- Treatment
- Malabsorption
- Diagnosis
- Evaluation of Suspected Malabsorption
- Specific Disorders Associated With Malabsorption
- Nonalcoholic Fatty Liver Disease
- Nonalcoholic fatty liver disease
- Epidemiology of NAFLD
- Risk Factors for NAFLD
- Pathophysiology of NAFLD
- Clinical Manifestations of NAFLD
- Diagnosis of NAFLD (Figure 3)
- Pancreatic Cancer
- Epidemiology
- Types of Pancreatic Cancer
- Risk Factors for Pancreatic Ductal Adenocarcinoma
- Screening
- Presentation and Diagnosis
- Treatment
- Managing Symptoms and Complications
- Summary
- Tumors of the Colon and Rectum
- Background, Epidemiology, and Etiology
- Adenomatous Polyps
- Familial Colorectal Cancer Syndromes
- Inflammatory Bowel Disease
- Screening the Average-Risk Patient
- Screening the High-Risk Patient
- Surgery for Colonic Tumors
- Surgery for Rectal Tumors
- Surgery for High-Risk Conditions
- Pathologic Staging and Adjuvant Therapy
- Metastatic Disease
- Surveillance
- Tumors of the Stomach
- Gastric Adenocarcinoma
- Gastrointestinal Stromal Tumors
- Neuroendocrine Tumors
- Gastric Lymphomas
- Section V. Endocrine and Metabolic Disorders
- Acromegaly
- Physiology, Biochemistry, and Regulation of the GH/IGF-1 Axis
- Etiopathogenesis of Growth Hormone–Secreting Tumors
- Clinical Manifestations
- Mortality
- Biochemical Diagnosis
- Imaging
- Treatment
- Adrenocortical Insufficiency
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Acknowledgments
- Cushing’s Syndrome
- Definition and Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Diabetes Insipidus
- Physiology of Antidiuretic Hormone
- Pathophysiology of Diabetes Insipidus
- Clinical Causes
- Clinical Manifestations
- Diagnosis
- Treatment
- Diabetes Mellitus in Adults
- Epidemiology
- Diagnosis and Classification of Diabetes and Prediabetes
- Diabetes Is Classified into Four Categories
- Clinical Manifestations
- Long-Term Implications of Glycemic Control
- Prevention
- General Medical Management
- General Goals
- Monitoring
- Frequency of Clinical Visits
- Early Detection of Complications
- Lifestyle
- Diet
- Exercise
- Weight Loss
- Pharmacologic Therapy
- Hypoglycemia
- Diabetic Ketoacidosis
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Prevention
- Gender Affirming Care
- Epidemiology
- Structural Determinants of Health Outcomes
- Evaluation
- Treatment
- Youth
- Other Considerations
- Gout and Hyperuricemia
- Epidemiology
- Pathophysiology and Risk Factors
- Diagnosis
- Treatment
- Hyperaldosteronism
- Introduction
- Pathophysiology
- Clinical Manifestations
- Evaluation
- Treatment
- Hyperlipidemia
- Pathophysiology
- Evaluation
- Treatment
- Hyperparathyroidism and Hypoparathyroidism
- Primary Hyperparathyroidism
- Secondary Hyperparathyroidism
- Hypoparathyrodism
- Hyperprolactinemia
- Biochemistry and Physiology of Prolactin
- Pathophysiology of Hyperprolactinemia
- Etiology of Hyperprolactinemia
- Epidemiology and Natural History of Prolactinoma
- Clinical Manifestations
- Laboratory Evaluation
- Neuroimaging
- Visual Field Testing
- Diagnosis
- Differential Diagnosis
- Management of Secondary Hyperprolactinemia
- Management of Prolactinoma
- Hyperthyroidism
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Hypokalemia and Hyperkalemia
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Complications
- Hyponatremia
- Clinical Presentation
- Regulation of Water Balance
- Central Nervous System Response to Hyponatremia/Hypoosmolality
- Classification and Differential Diagnosis of Hyponatremia
- Management
- Overcorrection of Hyponatremia
- Summary
- Hypopituitarism
- Epidemiology
- Pathophysiology
- Prevention
- Clinical Manifestations
- Detailed Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Special Circumstances
- Complications
- Conclusion
- Hypothyroidism
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Obesity in Adults
- Epidemiology
- Diagnosis
- Treatment
- Parenteral Nutrition in Adults
- Indications and Contraindications
- Assessment of Nutritional Status
- Estimating Nutritional Requirements
- Composition of Central and Peripheral Venous Solutions
- Administration and Venous Access
- Infusion and Patient Monitoring
- Patients With Special Needs
- Common Complications and Management
- Pheochromocytoma
- Epidemiology
- Genetics
- Clinical Manifestations
- Differential Diagnosis
- Biochemical Evaluation
- Localization of Pheochromocytoma
- Treatment
- Hypertensive Crisis
- Metastatic Pheochromocytoma
- Prognosis and Monitoring
- Thyroid Cancer
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- Management of Complications
- Conclusion
- Thyroiditis
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis and Differential Diagnosis
- Treatment
- Monitoring
- Section VI. Hematology
- Acute Leukemia in Adults
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment of Acute Myeloid Leukemia
- Treatment of Acute Lymphoblastic Leukemia
- Immune-Based Therapies in Acute Leukemia
- Monitoring
- Management of Complications
- Blood Component Therapy and Transfusion Reactions
- Therapeutic Use of Blood Components
- Plasma
- Transfusion Reactions
- Chronic Leukemias
- Chronic Myelogenous Leukemia
- Chronic Lymphocytic Leukemia
- Disseminated Intravascular Coagulation
- Introduction
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Therapy
- Hemochromatosis
- Clinical Features
- Diagnosis
- Family Studies
- Treatment
- Hemolytic Anemias
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Therapy
- Management of Complications
- Hemophilia and Related Conditions
- Hemophilia A and Hemophilia B
- Von Willebrand Disease
- Rare Bleeding Disorders
- Hodgkin Lymphoma
- Epidemiology
- Pathology
- Risk Factors
- Clinical Presentation
- Diagnosis
- Staging and Risk Prognostication
- Treatment
- Response Assessment
- Complications and Long-Term Monitoring
- Iron Deficiency Anemia
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Management of Complications
- Multiple Myeloma
- Epidemiology
- Risk Factors
- Clinical Manifestations
- Diagnosis
- Treatment
- Myelodysplastic Syndromes
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Classification and Risk Stratification
- Treatment
- Conclusion and Future Direction
- Non-Hodgkin Lymphoma
- Epidemiology
- Etiology and Risk Factors
- Screening
- Diagnosis
- Classification
- Prognosis
- Treatment
- Follow-Up of Long-Term Survivors
- Pernicious Anemia/Megaloblastic Anemia
- Introduction
- Epidemiology
- Etiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Prevention
- Treatment
- Complications and Long-Term Monitoring
- Platelet-Mediated Bleeding Disorders
- Clinical Manifestations
- Quantitative Platelet Disorders (Thrombocytopenia)
- Qualitative Platelet Function Disorders
- Polycythemia Vera
- Presentation
- Diagnosis and Differential Diagnosis
- Prognosis
- Treatment
- Porphyrias
- Pathophysiology and Clinical Manifestations
- Diagnosis
- Management
- Sickle Cell Disease
- Epidemiology
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Treatment
- Thalassemia
- Globin Gene Arrangements
- Pathophysiology
- β-Thalassemia Major
- β-Thalassemia Intermedia
- β-Thalassemia Minor
- α-Thalassemia
- Thrombotic Thrombocytopenic Purpura
- Pathophysiology
- Classification
- Clinical Presentation
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Prognosis
- Section VII. Head and Neck
- Dry Eye Syndrome
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Complications
- Glaucoma
- Primary Open Angle Glaucoma
- Visual Impairment and Blindness
- Acute Angle Closure Glaucoma
- Ménière’s Disease
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Complications
- Conclusion
- Otitis Externa
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- Complications
- Otitis Media
- Epidemiology
- Risk Factors
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Conclusion
- Red Eye
- Physical Examination
- Conjunctivitis
- Subconjunctival Hemorrhage
- Corneal Abrasion
- Other Causes of Red Eye
- Rhinosinusitis
- Epidemiology of Acute Rhinosinusitis and Predisposing Factors
- Pathogenesis and Etiology of Rhinosinusitis
- Diagnosis of Acute Rhinosinusitis
- Treatment of Acute Rhinosinusitis
- Complications and Referral
- Temporomandibular Disorders
- Epidemiology
- Signs and Symptoms
- Anatomy and Pathophysiology
- Etiology
- History and Examination
- Treatment
- Uveitis
- Current Diagnosis
- Clinical Features and Diagnosis
- Current Therapy
- Vision Rehabilitation
- Four Aspects of Vision Loss
- Comprehensive Vision Rehabilitation
- How Blind Is Blind?
- Vision Rehabilitation Techniques and Devices
- Optical Problems
- Retinal Problems
- Neural Processing Problems
- Patient-Centered Functional Priorities
- Section VIII. Infectious Diseases
- Amebiasis
- Epidemiology and Risk Factors for Acquisition
- Pathophysiology and Susceptible Host Factors to Invasive Diseases
- Clinical Manifestations and Complications of Amebiasis
- Diagnosis
- Therapy
- Monitoring After Treatment and Disease Prevention
- Anthrax
- Background
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Prognosis
- Prevention
- Babesiosis
- Epidemiology
- Clinical Features
- Therapy
- Bacterial Meningitis
- Diagnosis
- Antibiotic Management
- Adjunctive Therapy
- Vaccination Prevention
- Outcomes/Sequelae
- Brucellosis
- Epidemiology
- Risk Factors
- Pathophysiology
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Prevention
- Clostridioides difficile Colitis
- Epidemiology and Risk Factors
- Microbiology and Pathophysiology
- Clinical Features
- Differential Diagnosis
- Diagnosis
- Treatment
- Monitoring
- Complications and Recurrence
- Prevention
- Cat Scratch Disease
- Epidemiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Prevention
- Chikungunya
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Cholera
- Pathophysiology
- Clinical Presentation and Diagnosis
- Treatment
- Prevention
- COVID-19
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Conclusions
- Ebola Virus Disease
- Epidemiology
- Risk Factors/Transmission
- Pathophysiology
- Clinical Manifestations and Laboratory Findings
- Diagnosis
- Differential Diagnosis
- Therapy
- Long-Term Follow-up
- Prevention
- Monitoring
- Foodborne Illnesses
- Classification of Foodborne Illnesses
- Bacteria
- Nontyphoidal Salmonellosis
- Viruses
- Other Pathogens
- Giardiasis
- Background
- Organism
- Epidemiology
- Risk Factors
- Pathogenesis
- Prevention
- Clinical Features
- Diagnosis
- Treatment
- Human Immunodeficiency Virus: Treatment and Prevention
- Introduction
- Pathophysiology
- Natural History
- Diagnosis
- Consent
- Screening
- Approach to the Patient with HIV Infection
- Antiretroviral Therapy
- Treatment Failure
- Drug Resistance and Resistance Testing
- Adverse Drug Reactions and Drug-Drug Interactions
- Complications
- Management of Human Immunodeficiency Virus in Pregnancy and Women of Childbearing Potential
- Preexposure Prophylaxis of Human Immunodeficiency Virus Infection
- Initiating Preexposure Prophylaxis
- Postexposure Prophylaxis of Human Immunodeficiency Virus Infection
- Occupational Exposure
- Initial Laboratory Evaluation
- Initiating Postexposure Prophylaxis/Choosing Appropriate Postexposure Prophylaxis Therapy
- Infectious Mononucleosis
- Epidemiology and Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Influenza
- Microbiology
- Prevention
- Evaluation
- Complications
- Chemoprophylaxis
- Treatment
- Leishmaniasis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Leprosy
- Epidemiology
- Risk Factors
- Prevention
- Pathophysiology
- Clinical Manifestations
- Treatment
- Complications
- Acknowledgment
- Lyme Disease and Post-Treatment Lyme Disease Syndrome
- Epidemiology and Ecology
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Relapse Versus Reinfection
- Post-Treatment Lyme Disease Syndrome and “Chronic” Lyme Disease
- Chemoprophylaxis
- Treatment
- Malaria
- Introduction
- Epidemiology
- Parasite Life Cycle
- Malaria Immunity
- Clinical Manifestations
- Severe or Complicated Malaria
- Cerebral Malaria
- Respiratory Failure/Respiratory Distress Syndrome
- Acute Kidney Injury
- Malaria During Pregnancy
- Non-falciparum Malaria
- Laboratory Diagnosis
- Antimalarial Drugs
- Treatment of Uncomplicated Malaria
- Treatment of Severe Malaria
- Antimalarial Drugs in Pregnancy
- Treatment of Pediatric Patients
- Prevention of Malaria
- Measles (Rubeola)
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Signs and Symptoms
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Methicillin-Resistant Staphylococcus Aureus
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Treatment
- Mumps
- Epidemiology
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy (or Treatment)
- Complications
- Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
- Definition
- Epidemiology
- Pathophysiology
- Clinical Features and Diagnosis
- Treatment
- Things That Should Not Be Done
- Prognosis
- Monitoring
- Necrotizing Skin and Soft-Tissue Infections
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- Complications
- Osteomyelitis
- Introduction
- Epidemiology
- Pathogenesis
- Etiology
- Clinical Manifestations
- Diagnosis/Confirmation
- Treatment
- Conclusion
- Plague
- Epidemiology
- Modes of Transmission
- Bioterrorism Threat
- Pathogenesis and Clinical Syndromes
- Diagnosis
- Treatment
- Prevention and Control
- Post-Acute Covid syndrome
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- Complications
- Acknowledgment
- Psittacosis
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Complications
- Q Fever
- Clinical Features
- Diagnosis
- Treatment
- Prevention
- Rabies
- Pathogenesis
- Clinical Features
- Epidemiology
- Diagnosis
- Prevention
- Management of Human Rabies
- Rat-Bite Fever
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Relapsing Fever
- Epidemiology
- Clinical Diagnosis
- Laboratory Diagnosis
- Treatment
- Jarisch-Herxheimer Reaction
- Outcome
- Prevention
- Rubella and Congenital Rubella
- Pathophysiology and Virology
- Epidemiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Prevention
- Eradication and Future Goals
- Salmonellosis
- Microbiology
- Epidemiology
- Pathogenesis
- Clinical Presentation
- Diagnosis
- Treatment
- Chronic Carriage
- Prevention
- Sepsis
- Epidemiology
- Etiology
- Microbiology
- Definitions
- Pathophysiology
- Diagnosis
- Treatment
- Summary
- Smallpox
- The Agent
- Epidemiology
- Clinical Presentation
- Complications
- Differential Diagnosis (Figure 2)
- Diagnosis
- Treatment
- Vaccines and Vaccination
- Use in Warfare
- Tetanus
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Prevention
- Tickborne Rickettsial Diseases (Rocky Mountain Spotted Fever and Other Spotted Fever Group Rickettsioses, Ehrlichioses, and Anaplasmosis)
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring and Complications
- Prevention
- Toxic Shock Syndrome
- Introduction
- Historical Aspects
- Pathogenesis
- Clinical Features
- Management
- New Research and Developments
- Toxoplasmosis
- Epidemiology and Risk Factors
- Pathophysiology
- Clinical Presentation in the Immunocompetent
- Clinical Presentation in Immunocompromised Patients
- Toxoplasmosis of the Eye
- Maternal Infection and Congenital Toxoplasmosis
- Diagnosis in the Immunocompetent
- Diagnosis in the Immunocompromised
- Treatment
- T gondii Infection During Pregnancy in HIV-Positive Women
- Prevention
- Screening
- Vaccine
- Typhoid Fever
- Epidemiology
- Pathogenesis and Clinical Features
- Current Pattern of Antimicrobial Susceptibility
- Diagnosis
- Treatment
- Prevention
- Varicella (Chickenpox)
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Herpes Zoster
- Whooping Cough (Pertussis)
- Epidemiology
- Transmission
- Microbiology and Pathophysiology
- Immunity
- Clinical Symptoms
- Diagnosis
- Treatment
- Prevention
- Yellow Fever
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Zika Virus Disease
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Section IX. Neurological System
- Acute Facial Paralysis
- Epidemiology and Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis and Differential Diagnosis
- Treatment
- Monitoring and Complications
- Alzheimer’s Disease
- Screening
- Risk Factors and Prevention
- Diagnosis
- Treatment
- Monitoring
- Brain Tumors
- Metastatic Tumors
- Meningiomas
- Gliomas
- Primary Central Nervous System Lymphoma
- Gilles De La Tourette Syndrome
- Clinical Manifestations
- Comorbidities
- Diagnosis
- Treatment
- Complications
- Summary
- Intracerebral Hemorrhage
- Introduction
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- Complications
- Prevention
- Ischemic Cerebrovascular Disease
- Prevention
- Management of Carotid Stenosis
- Management of Patent Foramen Ovale
- Management of Acute Ischemic Stroke
- Migraine
- Definition
- Epidemiology
- Risk Factors
- Pathophysiology
- Diagnosis and Workup
- Treatment
- Acute Treatment
- Preventive Treatment
- Chronic Migraine Treatment
- Monitoring
- Multiple Sclerosis
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Myasthenia Gravis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Symptomatic Therapy
- Corticosteroids
- Thymectomy
- Other Immunomodulatory Therapies
- Treatment Considerations in Pregnancy
- Monitoring
- Complications
- Neurofibromatosis (Type 1)
- Introduction and Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Surveillance and Therapy
- Management of Complications
- Nonmigraine Headache
- Evaluation and Diagnosis
- Headache Type and Therapy
- Treatment of Tension Headache
- Cluster Headache (Trigeminal Autonomic Cephalalgia)
- Treatment of Cluster Headache
- Neuralgia
- Treatment of Neuralgia
- Optic Neuritis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment and Monitoring
- Complications
- Parkinson Disease
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications and Nonmotor Symptoms
- Rehabilitation of the Stroke Patient
- Hemiparesis
- Dysphagia
- Hemiplegic Shoulder Pain
- Spasticity
- Cognitive Dysfunction
- Depression and Neuropharmacology
- Bladder Dysfunction
- Mobility and Use of Adaptive Equipment
- Falls
- Visual Impairment
- Brain-Based Therapies: Noninvasive Brain Stimulation
- Robotics
- Virtual Reality
- Conclusions
- Seizures and Epilepsy in Adolescents and Adults
- Epidemiology
- Classification
- Diagnosis
- Differential Diagnosis
- Treatment
- Characteristics of Specific Antiseizure Drugs
- Special Populations
- Sleep Disorders
- The International Classification of Sleep Disorders
- Clinical Approach to the Sleep Medicine Patient: The Interview and Examination
- Diagnostic Tools in the Sleep Laboratory
- Diagnostic and Therapeutic Approach to Common Sleep Disorders
- Narcolepsy and Central Disorders of Hypersomnolence
- Sleep-Related Movement Disorders
- Conclusions
- Sports-Related Head Injuries
- Introduction and Epidemiology
- Risk Factors
- Pathophysiology
- Assessment and Diagnosis of Sports-Related Head Injury
- Clinical Manifestations
- Treatment
- Monitoring Concussions
- Management of Concussion Complications
- Prevention
- Targeted Temperature Management (Therapeutic Hypothermia)
- Introduction
- Initiation
- Maintenance
- Rewarming
- Post-Therapeutic Hypothermia/Prognosis
- Trigeminal Neuralgia
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Management of Complications
- Viral Meningitis
- Epidemiology
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Section X. Psychiatric Disorders
- Alcohol Use Disorder
- Classification
- Epidemiology
- Diagnosis
- Treatment
- Comorbidities
- Uncertainties and Controversies
- Autism
- Epidemiology
- Risk Factors, Etiology, and Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Screening, Clinical Assessment, Intervention, and Monitoring
- Pharmacotherapy
- Delirium
- Epidemiology
- Pathophysiology
- Risk Factors
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Monitoring
- Prevention
- Treatment
- Complications
- Special Considerations
- Depressive, Bipolar, And Related Mood Disorders
- Introduction
- Mood Disorders
- Epidemiology for Unipolar and Bipolar Disorders
- Differential Diagnosis
- Treatment
- Psychopharmacology
- Psychotherapy
- Mood Dysregulation
- Clinical Course and Prognosis of Mood Disorders
- Prevention
- Drug Use Disorders
- Epidemiology
- Diagnosis
- Tobacco and Nicotine
- Cannabis
- Cocaine, Methamphetamine, and Other Stimulants
- Opioids
- Sedative-Hypnotics
- Conclusion
- Eating Disorders
- Bulimia Nervosa
- Binge-Eating Disorder
- Anorexia Nervosa
- Avoidant-Restrictive Food Intake Disorder
- Generalized Anxiety Disorder
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment and Monitoring
- Complications
- Conclusion
- Obsessive-Compulsive Disorder
- Epidemiology
- Risk Factors, Etiology, and Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment and Monitoring
- Panic Disorder
- Epidemiology
- Risk Factors
- Diagnosis
- Clinical Manifestations
- Differential Diagnosis
- Treatment
- Posttraumatic Stress Disorder
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment and Monitoring
- Complications
- Conclusion
- Schizophrenia
- Epidemiology and Risk Factors
- Diagnosis
- Treatment
- Comorbidity
- Conclusions
- Section XI. Respiratory System
- Acute Bronchitis and Other Viral Respiratory Infections
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy (or Treatment)
- Acute Respiratory Failure
- Definitions and Pathophysiology
- Treatment
- Specific Causes of Acute Respiratory Failure
- Asthma in Adolescents and Adults
- Diagnosis
- Assessment
- Long-Term Management
- Follow-Up
- Treatment of Exacerbations
- Summary
- Atelectasis
- Etiology
- Pathophysiology
- Clinical Presentation
- Diagnosis
- Treatment
- Bacterial Pneumonia
- Epidemiology
- Etiology
- Diagnosis
- Treatment Setting
- Treatment
- Prevention
- Blastomycosis
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Blastomycosis in Special Populations
- Diagnosis
- Treatment
- Chronic Obstructive Pulmonary Disease
- Epidemiology
- Risk Factors
- Pathophysiology
- Diagnosis
- Differential Diagnosis
- Treatment of Stable Chronic Obstructive Pulmonary Disease
- Treatment of Exacerbations of Chronic Obstructive Pulmonary Disease
- COCCIDIOIDOMYCOSIS
- Clinical Manifestations
- Diagnosis
- Treatment
- Cystic Fibrosis
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Management of Other Complications
- Histoplasmosis
- Mycology and Pathogenesis
- Epidemiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Hypersensitivity Pneumonitis
- Pathophysiology
- Clinical Presentation and Diagnosis
- Treatment
- Legionellosis (Legionnaires’ Disease and Pontiac Fever)
- Epidemiology
- Clinical Features
- Diagnosis
- Treatment
- Lung Abscess
- Definition and Classification
- Epidemiology and Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Prognosis
- Lung Cancer
- Epidemiology
- Risk Factors
- Prevention
- Early Detection
- Clinical Manifestations
- Diagnostic Techniques
- Staging
- Assessing Treatment Candidacy
- Surgical Approach to Lung Cancer
- Treatment: Non–Small Cell Lung Cancer
- Locally Advanced Lung Cancer
- Oligometastatic Disease
- Treatment Small Cell Lung Cancer
- Monitoring
- Summary
- Obstructive Sleep Apnea
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Diagnosis
- Treatment
- Monitoring
- Pleural Effusion and Empyema
- Etiology
- Diagnosis
- Treatment
- Pneumoconiosis: Asbestosis and Silicosis
- Asbestosis
- Silicosis
- Disclaimer
- Pulmonary Hypertension
- Definition and Classification
- Clinical Manifestations
- Diagnosis
- Risk Stratification
- Treatment
- Monitoring
- Sarcoidosis
- Epidemiology
- Immunopathogenesis
- Clinical Features and Clinical Course
- Diagnosis and Initial Workup
- Treatment
- Tuberculosis and Other Mycobacterial Diseases
- Overview
- Tuberculosis
- Nontuberculous Mycobacteria
- Venous Thromboembolism
- Pathophysiology/Risk Factors
- Epidemiology and Natural History
- Diagnosis of Deep Venous Thrombosis
- Diagnosis of PE
- Diagnosis of Recurrent DVT
- Treatment of Venous Thromboembolism
- Prevention of Venous Thromboembolism
- Viral and Mycoplasmal Pneumonias
- Influenza (Human, Avian, and Swine)
- Anti-Influenza Therapy
- COVID-19 Therapy
- Mycoplasma Pneumoniae
- Viral Respiratory Infections
- Common Colds
- Influenza-Like Illness
- Croup
- Bronchiolitis
- Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
- Section XII. Rheumatology and the Musculoskeletal System
- Axial Spondyloarthritis
- Definition and Spectrum of the Disease
- Epidemiology
- Pathogenesis
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Bursitis and Tendinopathy
- Tendinopathy
- Bursitis
- Common Sports Injuries
- Ankle Injuries
- Hand Injuries
- Overuse Injuries
- Connective Tissue Disorders
- Lupus Erythematosus
- Dermatomyositis and Polymyositis
- Scleroderma
- Fibromyalgia
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Juvenile Idiopathic Arthritis
- Risk Factors/Prevention
- Pathophysiology
- Oligoarticular Juvenile Idiopathic Arthritis
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Polyarticular Juvenile Idiopathic Arthritis
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Enthesitis-Related Arthritis
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Juvenile Psoriatic Arthritis
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Systemic Juvenile Idiopathic Arthritis
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Osteoarthritis
- Pathogenesis
- Risk Factors
- Clinical Features
- Current Therapy
- Nonpharmacologic Therapies
- Pharmacotherapy
- Intra-articular Injections
- Surgical Management of Osteoarthritis
- Conclusions
- Osteoporosis
- Epidemiology
- Screening
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Prevention
- Treatment
- Pharmacologic Treatment
- Paget’s Disease of Bone
- Etiology
- Epidemiology
- Clinical Presentation
- Diagnosis
- Treatment
- Polymyalgia Rheumatica and Giant Cell Arteritis
- Primary Polymyalgia Rheumatica
- Giant Cell Arteritis
- Psoriatic Arthritis
- Epidemiology
- Risk Factors
- Pathophysiology
- Infection and Trauma
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy (or Treatment)
- Monitoring
- Management of Complications
- Rheumatoid Arthritis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Synthetic Disease Modifying Antirheumatic Drugs
- Biologics
- Monitoring
- Management of Complications
- Section XIII. Sexually Transmitted Diseases
- Chlamydia Trachomatis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Condylomata Acuminata
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Genital Ulcer Disease: Chancroid, Granuloma Inguinale, and Lymphogranuloma
- Chancroid
- Granuloma Inguinale (Donovanosis)
- Lymphogranuloma Venereum
- Management of Sex Partners
- Gonorrhea
- Epidemiology
- Risk Factors
- Pathophysiology
- Screening and Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Management of Complications
- NonGonococcal Urethritis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Therapy/Treatment
- Monitoring
- Complications
- Syphilis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Screening
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Section XIV. Skin Disease
- Acne Vulgaris
- Epidemiology
- Prevention
- Pathophysiology
- Diagnosis
- Clinical Manifestations
- Differential Diagnosis
- Treatment
- Atopic Dermatitis
- Pathophysiology
- Diagnosis and Clinical Assessment
- Management of Atopic Dermatitis and Associated Conditions
- Referral to Specialists
- Autoimmune Bullous Diseases
- Epidemiology
- Pathophysiology
- Diagnosis
- Pemphigus
- Bullous Pemphigoid
- Treatment
- Mucous Membrane Pemphigoid
- Linear IgA Bullous Dermatosis/Chronic Bullous Disease of Childhood
- Diagnosis
- Epidermolysis Bullosa Acquisita
- Dermatitis Herpetiformis
- Bacterial Diseases of the Skin
- Common Infections
- Invasive Infections
- Contact Dermatitis
- Diagnosis
- Treatment
- Cutaneous T-Cell Lymphomas, Including Mycosis Fungoides and Sézary Syndrome
- Cutaneous T-Cell Lymphomas
- Standard Diagnosis and Staging Methods
- Mycosis Fungoides, Sézary Syndrome, and Variants
- Lymphoproliferative Disorders Associated with Mycosis Fungoides and Sézary Syndrome
- Cutaneous Vasculitis
- Leukocytoclastic Vasculitis
- Cutaneous Vasculitis Associated with Systemic Vasculitis
- Diseases of the Hair
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Diseases of the Mouth
- Caries
- Periodontitis
- Necrotizing Ulcerative Gingivitis
- Odontogenic Infections
- Oral Ulcers
- Oral Soft Tissue Lesions
- Oral Candidiasis
- Xerostomia
- Osteonecrosis of the Jaw
- Antibiotic Prophylaxis Before Dental Procedures
- Diseases of the Nail
- Nail Anatomy
- Noninfectious Nail Disorders
- Subungual Hematoma
- Acute Paronychia
- Chronic Paronychia
- Myxoid Cysts
- Nail Infections
- Pseudomonas Nail Infection
- Periungual Verrucae
- Erythema Multiforme
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations and Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring and Complications
- Fungal Infections of The Skin
- Superficial Mycoses Dermatophytes
- Treatment
- Additional Comments
- Acknowledgment
- Keloids
- Epidemiology
- Pathophysiology
- Risk Factors
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Intralesional Corticosteroid
- Surgical Excision
- Silicone Gel Sheeting
- Cryotherapy
- Pressure Therapy
- Intralesional 5-Fluorouracil
- Surgical Excision
- Postoperative Radiation Therapy
- Monitoring
- Complications
- Melanoma
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Nevi
- Acquired Melanocytic Nevi
- Recurrent Melanocytic Nevi
- Halo (Melanocytic) Nevi
- Congenital Melanocytic Nevi
- Blue Nevi
- Spitz Nevi
- Dysplastic Melanocytic Nevi
- Nonmelanoma Cancer of The Skin
- Basal Cell Carcinoma
- Squamous Cell Carcinoma
- Neoplasms of Adnexal Origin
- Sebaceous Carcinoma
- Fibrohistiocytic Malignancies
- Vascular Malignancies
- Other Nonmelanoma Skin Cancers
- Papulosquamous Eruptions
- Epidemiology
- Risk Factors
- Pathophysiology
- Diagnosis
- Differential Diagnosis
- Clinical Manifestations
- Treatment
- Complications
- Parasitic Diseases of the Skin
- Diseases Caused by Protozoa
- Diseases Caused by Helminths
- Diseases Caused by Arthropoda
- Pigmentary Disorders
- Definition
- Evaluation
- General Recommendations for All Pigmentary Disorders
- Hyperpigmentation
- Hypopigmentation or Depigmentation
- Premalignant Skin Lesions
- Actinic Keratoses and Actinic Cheilitis
- Porokeratoses
- Management of Complications
- Pressure Injury
- Epidemiology
- Risk Factors
- Pathophysiology
- Differential Diagnosis
- Diagnosis
- Therapy
- Monitoring
- Pruritus Ani and Vulvae
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis of Pruritus Ani and Vulvae
- Physical Examination
- Laboratory Tests
- Procedures
- Differential Diagnosis
- Prevention and Treatment
- Complications
- Referral
- Monitoring and Prognosis
- Pyoderma Gangrenosum
- Pathophysiology and Epidemiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Rosacea
- Diagnosis
- Treatment
- Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis
- Epidemiology
- Risk Factors
- Pathophysiology
- Differential Diagnosis
- Diagnosis
- Therapy
- Monitoring
- Sunburn
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring and Complications
- Urticaria and Angioedema
- Classification
- Diagnosis
- Treatment
- Venous Ulcers
- Epidemiology
- Pathophysiology
- Evaluation and Diagnosis
- Complications
- Treatment
- Viral Diseases of the Skin
- Herpes Simplex Viruses 1 and 2
- Varicella Zoster Virus
- Herpes Zoster
- Hand-Foot-and-Mouth Disease
- Parvovirus B19
- Molluscum Contagiosum
- Orf and Milker’s Nodules
- Warts (Verrucae)
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Risk Factors
- Differential Diagnosis
- Treatment
- Section XV. Urogenital Tract
- Acute Kidney Injury
- Background/Definitions
- Epidemiology
- Etiology
- Prerenal
- Intrinsic
- Postrenal
- Approach to Diagnosis
- Approach to Treatment
- Prognosis and Outcomes
- Developing Issues—Biomarkers
- Chronic Kidney Disease
- Prevalence of Chronic Kidney Disease
- Risk Factors for Chronic Kidney Disease
- Approach to the Diagnosis of Chronic Kidney Disease
- Management of Chronic Kidney Disease
- General Approach to Treatment of Chronic Kidney Disease
- Dietary Protein Restriction
- Clinical Manifestations of Kidney Failure
- Measures Designed to Treat Comorbidity in Kidney Disease
- Malignant Tumors of the Urogenital Tract
- Prostate Cancer
- Benign and Malignant Renal Tumors
- Urothelial Cell Carcinoma
- Primary Carcinoma of the Prostate and Urethra
- Penile Cancer
- Testicular Cancer
- Nephrolithiasis
- Pathophysiology
- Prevention
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Monitoring
- Primary Glomerular Disease
- Clinical Presentation
- Diagnosis of the Primary Glomerular Diseases
- General Management of Primary Glomerular Diseases
- Therapy of Specific Glomerular Diseases
- Primary Membranous Glomerulonephritis
- IgA Nephropathy
- Postinfectious Glomerulonephritis
- Membranoproliferative Glomerulonephritis due to Alternate Complement Pathway Abnormalities
- Fibrillary Glomerulonephritis
- Pyelonephritis
- Epidemiology
- Pathophysiology and Microbial Etiology
- Risk Factors
- Clinical Manifestations
- Diagnosis
- Treatment Considerations
- Outpatient Management
- Inpatient Management
- Complications
- Prevention
- Trauma to the Genitourinary Tract
- Renal Trauma
- Ureteral Trauma
- Bladder Trauma
- Urethral Trauma
- Trauma to the External Genitalia
- Conclusion
- Urethral Stricture Disease
- Diagnosis
- Long-Term Treatment
- Urinary Incontinence
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestation
- Diagnosis
- Differential Diagnosis
- Therapy
- Complications
- Section XVI. Men's Health
- Benign Prostatic Hyperplasia
- Epidemiology
- Pathophysiology
- Symptoms
- Diagnosis
- Treatment
- Summary
- Epididymitis And Orchitis
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy/Treatment
- Complications
- Erectile Dysfunction
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy (or Treatment)
- Monitoring
- Management of Complications
- Prostate Cancer
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Management of Complications
- Prostatitis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy (or Treatment)
- Monitoring
- Complications
- Urinary Tract Infections in the Male
- Definitions
- Introduction
- Incidence and Epidemiology
- Pathophysiology
- Clinical Manifestations
- Differential Diagnosis
- Clinical Evaluation
- Treatment
- Monitoring and Prevention
- Management of Complications
- Special Considerations
- Section XVII. Women's Health
- Abnormal Uterine Bleeding
- Epidemiology
- Pathophysiology
- Diagnosis
- Treatment
- Amenorrhea
- Etiology
- Evaluation
- Diagnoses and Management
- Bacterial Infections of the Urinary Tract in Women
- Acute Cystitis (Urinary Tract Infection)
- Urethritis
- Asymptomatic Bacteruria
- Recurrent Cystitis
- Benign Breast Disease
- Presentation and Workup
- Benign Lesions
- High-Risk Evaluation and Management
- Chemoprevention
- Breast Cancer
- Overview
- Epidemiology
- Risk Factors
- Risk Reduction
- Clinical Manifestations
- Differential Diagnosis
- Diagnosis
- Pathophysiology
- Treatment
- Monitoring and Survivorship
- Cancer of the Endometrium
- Epidemiology
- Classification
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Staging
- Treatment
- Monitoring
- Cancer of the Uterine Cervix
- Epidemiology
- Pathophysiology
- Prevention and Screening
- Staging
- Diagnosis
- Treatment
- Conclusion
- Contraception
- Nonhormonal Methods
- Combined Hormonal Contraception
- Combined Oral Contraceptive Pills
- Contraceptive Patch
- Vaginal Ring
- Progestin-Only Contraceptives
- Permanent
- Emergency Contraception
- Counseling
- Dysmenorrhea
- Diagnosis
- Treatment
- Endometriosis
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis/Differential Diagnosis
- Medical Therapy
- Surgical Therapy
- Monitoring
- Female Sexual Dysfunction
- Epidemiology
- Pathophysiology, Diagnosis, Treatment: Decreased Libido
- Pathophysiology, Diagnosis, Treatment: Sexual Pain
- A Note About Atrophy
- Infertility
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Monitoring
- Menopause
- Epidemiology
- Risk Factors
- Clinical Manifestations and Pathophysiology
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Side Effects of Systemic Hormone Therapy
- Safety of Hormone Therapy
- Early/Induced Menopause
- Extended Use/Discontinuation of Systemic Hormone Therapy
- Financial Disclosure
- Ovarian Cancer
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Pelvic Inflammatory Disease
- Epidemiology
- Risk Factors
- Pathophysiology
- Clinical Presentation
- Diagnosis
- Differential Diagnosis
- Treatment
- Patient Monitoring and Counseling
- Complications
- Premenstrual Syndrome
- Symptoms
- Prevalence
- Morbidity
- Etiology
- Diagnosis
- Treatment
- Conclusions
- Uterine Leiomyoma
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment of Myomas
- Managing Complications
- Vulvar Neoplasia
- Benign Cystic Neoplasms
- Benign Solid Neoplasms
- Intraepithelial Neoplasms of the Vulva
- Invasive Vulvar Lesions
- Vulvovaginitis
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Section XVIII. Pregnancy and Antepartum Care
- Antepartum Care
- Antepartum Care
- Timeline of Routine Antepartum Care
- Common Concerns of the Antenatal Period
- Tests of Fetal Well-Being
- Ectopic Pregnancy
- Epidemiology
- Pathophysiology
- Risk Factors
- Diagnosis and Clinical Manifestations
- Transvaginal Ultrasonography
- Hormonal Assays
- Uterine Aspiration
- Treatment and Therapeutic Monitoring
- Surgical Management
- Medical Management
- Expectant Management
- Hypertension In Pregnancy
- Epidemiology
- Pathophysiology
- Prevention
- Diagnosis
- Management
- Complications
- Postpartum Care
- Postpartum Hemorrhage
- Postpartum Care After Hospital Dismissal
- Fever and Infection
- Immunization
- Breastfeeding
- Contraception
- Other Considerations
- Postpartum Depression
- Introduction
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Management of Complications
- Vaginal Bleeding in Pregnancy
- Vaginal Bleeding in Late Pregnancy
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Therapy
- Monitoring
- Complications
- Vaginal Bleeding in Early Pregnancy
- Pathophysiology
- Management
- Section XIX. Children's Health
- Acute Leukemia in Children
- Classification
- Epidemiology
- Prognosis
- Etiology
- Clinical Presentation
- Medical Emergencies in Childhood Leukemia
- Differential Diagnosis
- Risk Stratification
- Treatment
- Relapse
- Late Effects
- Adolescent Health
- Setting the Stage for the Adolescent Visit
- Consent and Confidentiality Laws—Consent Does Not Equal Confidential
- The HEADS Interview
- Pandemic/Post-pandemic Screening
- Summary
- Asthma in Children
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Medications
- Acute Asthma Exacerbations
- Monitoring
- Complications
- Attention-Deficit/Hyperactivity Disorder
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Therapy
- Monitoring
- When to Refer
- Bronchiolitis
- Background
- Epidemiology and Virology
- Coronavirus Disease 2019
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Outpatient Management
- Inpatient Management
- Complications
- Diabetes Mellitus in Children
- Type 1 Diabetes: Introduction
- Epidemiology
- Presentation
- Diagnosis
- Treatment of Type 1 Diabetes Mellitus
- Treatment of Diabetic Ketoacidosis
- Diabetes Self-Management Education
- Mental Health Considerations in Type 1 Diabetes Mellitus
- Goals of Therapy for Patients With Type 1 Diabetes Mellitus
- Sick Day Management
- Risk for Additional Autoimmune Disorders
- Screening for Complications of Type 1 Diabetes Mellitus
- Technologic Changes in the Care for Patients With Type 1 Diabetes Mellitus
- Type 2 Diabetes in Children
- Monogenic or Maturity-Onset Diabetes of Youth
- Encopresis
- Epidemiology
- Diagnosis
- Differential Diagnosis
- Pathophysiology
- Clinical Manifestations
- Treatment
- Epilepsy in Infants and Children
- Risk Factors
- Pathophysiology
- Clinical Manifestations
- Diagnosis and Management
- Comorbidities
- Differential Diagnosis
- Treatment
- Monitoring
- Complications
- Notice
- Infant Hyperbilirubinemia
- Background
- Risk Factors
- Pathogenesis
- Unconjugated Hyperbilirubinemia
- Conjugated Hyperbilirubinemia
- Prevention
- Diagnosis
- Treatment
- Phototherapy
- Exchange Transfusion
- Pharmacologic Treatment
- Complications
- Mitochondrial Disease
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Considerations
- Conflicts of Interest
- Multisystem Inflammatory Syndrome In Children Associated With Severe Acute Respiratory Syndrome Coronavirus 2 Infection
- Epidemiology
- Pathophysiology
- Clinical Manifestations
- Diagnosis
- Treatment
- Monitoring
- Complications
- Nocturnal Enuresis
- Epidemiology
- Risk Factors
- Pathogenesis
- Diagnosis
- Treatment
- Normal Infant Feeding
- Breast-feeding and Breast Milk
- Infant Formulas
- Micronutrients
- Defining Adequate Intake
- Introduction of Complementary Foods
- Summary
- Obesity IN CHILDREN
- Introduction
- Diagnosis
- Epidemiology
- Pathophysiology
- Clinical Manifestations and Associated Comorbidities
- Clinical Evaluation of the Child With Obesity
- Treatment: A Staged Approach to Prevention, Clinical Interventions, and Monitoring
- Lifestyle Interventions
- Pharmacologic Therapy
- Conclusion
- Parenteral Fluid Therapy For Infants And Children
- Introduction
- Maintenance Intravenous Fluid Therapy
- Resuscitation Intravenous Fluid Therapy
- Replacement Intravenous Fluids
- Sodium Disorders
- Pediatric Failure to Thrive
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Clinical Manifestations
- Differential Diagnosis
- Therapy
- Monitoring
- Complications
- Pediatric Sleep Disorders
- Introduction
- Clinical Approach
- Diagnostic Tools
- Common Pediatric Sleep Diagnoses and Treatment
- Resuscitation of the Newborn
- Transition From Fetal to Extrauterine Life
- Risk Factors for Newborn Resuscitation
- Reaction to Hypoxia and Asphyxia
- Preparation for Newborn Resuscitation
- Sequence of Newborn Resuscitation
- Special Considerations
- Urinary Tract Infections in Infants and Children
- Diagnosis
- Imaging
- Treatment
- Voiding Dysfunction
- Prophylaxis
- Section XX. Physical and Chemical Injuries
- Burns
- Epidemiology
- Risk Factors
- Prevention
- Pathophysiology
- Clinical Manifestations
- Special Situations
- Therapy and Treatment
- Complications
- Disturbances Due To Cold
- Accidental Systemic Hypothermia
- Epidemiology
- Pathophysiology
- Clinical Presentation
- Emergency Department Evaluation
- Rewarming Strategies
- Peripheral Cold Injuries
- Pathophysiology
- Clinical Presentation of Local Extremity Issues
- Treatment
- Sequelae
- Heat Illness
- Risk Factors
- Exercise-Associated Collapse
- Return to Play
- High Altitude Illness
- Epidemiology and Risk Factors
- Physiologic Adaptation and Pathophysiology
- Prevention
- Symptomatic Acclimatization and Disrupted Sleep
- High Altitude Headache
- High Altitude Syndromes
- Other High Altitude Disorders
- High Altitude Retinopathy (HAR)
- Chronic High Altitude Diseases
- Additional Considerations
- Children
- Pregnant Women
- Hypertension
- Coronary Artery Disease (CAD)
- Heart Failure
- Respiratory Conditions
- Diabetes Mellitus
- Marine Poisonings, Envenomations, and Trauma
- Ingestions
- Envenomations
- Trauma
- Medical Toxicology
- Introduction and Epidemiology
- Assessment and Maintenance of the Vital Functions
- Prevention of Absorption and Reduction of Local Damage
- Differential Diagnosis of Poisons on the Basis of Central Nervous System Manifestations
- Guidelines for In-Hospital Disposition
- Use of Antidotes
- Enhancement of Elimination
- Supportive Care, Observation, and Therapy for Complications
- Laboratory and Radiographic Studies
- Common Poisons
- Spider Bites and Scorpion Stings
- Spider Bites
- Scorpion Stings
- Venomous Snakebite
- Diagnostic and Management Overview
- Crotalid Envenomations
- Coral Snake Envenomations
- Exotic Snakebite
- Section XXI. Preventive Health
- Immunization Practices
- Definitions and Background
- Physiology of Vaccines
- Immunization Recommendations
- Disease Prevention
- COVID-19 Vaccines
- Pneumococcal Vaccine Update
- Immunization Responsibility
- General Principles for Vaccine Scheduling
- Route of Administration
- Storage
- Vaccine Safety
- Contraindications and Adverse Events
- Barriers
- Recording Vaccinations
- Special Populations
- Travel Medicine
- Vaccinations
- Routine Vaccines
- Recommended Travel Vaccines
- Required Vaccines
- Malaria
- Post-travel
- COVID-19
- Personal Protection Measures
- Traveler’s Diarrhea
- High-Altitude Illness
- Summary
- Section XXII. Emerging Therapies
- Genomic Testing
- Genotyping
- Cell-Free DNA
- Whole-Exome Sequencing/Genome Sequencing
- Conclusion
- Genomic Resources
- Monoclonal Antibodies
- Introduction
- Properties of Antibodies as Drugs
- Monoclonal Antibody Structure
- Therapeutic Uses of Monoclonal Antibodies
- Monoclonal Antibody Side Effects
- Monoclonal Antibody Nomenclature
- Examples of Monoclonal Antibodies Used in Clinical Practice
- Stem Cell Therapy
- Transplantation of Hematopoietic Stem Cells
- Mesenchymal Stem Cell Therapy for Acute Graft Versus Host Diseas
- Stem Cell Therapy in Knee Osteoarthritis (OA)
- Stem Cell Therapy for Cardiac Diseases
- Stem Cell Therapy for Neurologic Disorders
- Other Promising Indications for Stem Cell Therapy
- Section XXIII. Appendices and Index
- Biologic Agents Reference Chart
- Popular Herbs and Nutritional Supplements
- Toxic Chemical Agents Reference Chart
- Monkeypox
- Epidemiology
- Risk Factors
- Pathophysiology
- Prevention
- Vaccinations
- Preexposure Prophylaxis
- Postexposure Prophylaxis
- Pregnancy/Breastfeeding
- Children
- Clinical Manifestations
- Diagnosis
- Differential Diagnosis
- Treatment
- Complications
- Index
- IBC
- No. of pages: 1632
- Language: English
- Edition: 1
- Published: November 2, 2022
- Imprint: Elsevier
- eBook ISBN: 9780443105623
RK
Rick D. Kellerman
Affiliations and expertise
Professor and Chair Department of Family and Community Medicine, University of Kansas School of Medicine - Wichita, Wichita, KansasDR
David P. Rakel
Affiliations and expertise
Professor & Chair, Department of Family Medicine & Community Health, University of Wisconsin, Madison, Wisconsin