Conjugate Addition Reactions in Organic Synthesis
- 1st Edition, Volume 9 - June 15, 1992
- Imprint: Pergamon
- Author: P. Perlmutter
- Editor: Patrick Perlmutter
- Language: English
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 3 7 0 6 6 - 8
- Paperback ISBN:9 7 8 - 0 - 0 8 - 0 3 7 0 6 7 - 5
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 9 3 7 8 - 3
This book provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic… Read more
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Request a sales quoteThis book provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic synthesis. The book is organised in terms of the major classes of conjugate acceptors. Within each of these classes, the chemistry and applications of conjugate additions with several different categories of nucleophiles have been examined. Where several different nucleophiles achieve the same synthetic transformation, they are cross-referenced within the book and qualitative comparisons offered where appropriate. Examples of the use of conjugate additions in total synthesis of important molecules are included, with a special emphasis throughout the book on stereoselectivity. This will be a useful main text for graduate and postgraduate courses on conjugate addition reactions or the Michael reaction. It could also serve as a supplementary text for courses on topics such as the chemistry of organocopper reagents, enamines and carbanion chemistry.
For undergraduate and graduate students, academic and industrial scientists in organic chemistry.
Introduction. Organization of the book. History. Nomenclature, classification of reaction types and survey of conjugate receptors. Mechanism of conjugate additions. The nucleophiles. Intramolecular reactions. Tandem reactions. Alkenals and Acyclic Alkenones. Introduction. Intermolecular reactions. Intramolecular reactions. Cycloalkenones. Introduction. Intermolecular reactions. Intramolecular reactions. Alkenoic Acids and their Derivatives. Introduction. Intermolecular reactions. Intramolecular reactions. &agr;,&bgr;-Unsaturated Lactones and Lactams. Introduction. Stabilized carbanions. Organocopper reagents. Other organometallic reagents. Free radicals. Heteronucleophiles. Other Systems. Introduction. Nitroalkenes. Alkenylsulfoxides, phosphonates and related compounds. Quinones. Alkenylsilanes. Ketene acetals. Alkenylphosphonium salts. Activated Alkynes. Alkynones. Alkynoic acid derivatives. Alkynyl sulfoxides, and related sustems. Index.
- Edition: 1
- Volume: 9
- Published: June 15, 1992
- Imprint: Pergamon
- Language: English
- Hardback ISBN: 9780080370668
- Paperback ISBN: 9780080370675
- eBook ISBN: 9781483293783
PP
Patrick Perlmutter
Patrick Perlmutter is Adjunct Professor of Chemistry at La Trobe University in Australia. He has been a university academic for 35 years with a highly active research group specialising in synthesis and new synthetic methods including conjugate additions, catalysis, total synthesis, medicinal chemistry and chemical biology. His research group has generated approximately 200 peer-reviewed publications in that time.
Affiliations and expertise
Adjunct Professor of Chemistry
La Trobe University, AustraliaPP
P. Perlmutter
Affiliations and expertise
Department of Chemistry, Monash University, AustraliaRead Conjugate Addition Reactions in Organic Synthesis on ScienceDirect