Comprehensive Gynecology
- 8th Edition - May 8, 2021
- Imprint: Elsevier
- Authors: David M. Gershenson, Gretchen M Lentz, Rogerio A. Lobo
- Editor: Fidel A. Valea
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 6 5 3 9 9 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 7 9 0 7 8 - 9
With its trademark clear, concise writing style and evidence-based focus, Comprehensive Gynecology, 8th Edition, remains your #1 choice for practical, in-depth coverage of an… Read more
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Request a sales quoteWith its trademark clear, concise writing style and evidence-based focus, Comprehensive Gynecology, 8th Edition, remains your #1 choice for practical, in-depth coverage of any women’s health issue you’re likely to encounter. It covers all key issues in gynecology, now fully updated to include new information on topics such as laparoscopy and innovations in robotic surgery, reversible contraception, and advancements in treating endometriosis. For residents, specialists, primary care doctors, and other healthcare providers, Comprehensive Gynecology is an easy-to-access source of trusted information for everyday practice.
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Includes helpful features such as key references and terms, key points at the end of each chapter, summary boxes for quick reference, and new bolded text to highlight the most important concepts.
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Features newly improved artwork; a more cohesive, easy-to-navigate design throughout; and more clinical algorithms.
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Contains hundreds of illustrations and tables, anatomical figures, radiographs, and photographs, as well as 20 videos that address topics such as Pap smear techniques, hysteroscopic metroplasty, and endometriosis of the bladder.
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Brings you up to date with the latest applications in diagnostic and interventional ultrasound, issues in infertility, the latest research in menopause, and other essential aspects of today's practice.
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Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
OBGYN residents and practitioners
- Cover image
- Title page
- Table of Contents
- Copyright
- List of contributors
- Preface
- Video contents
- List of Tables
- List of Illustrations
- Part I. Basic Science
- 1. Fertilization and embryogenesis
- Meiosis, fertilization, implantation, embryonic development, and sexual differentiation
- The oocyte and meiosis
- Fertilization and early cleavage
- Implantation
- Development of the genitourinary system
- Molecular basis of sex differentiation
- Acknowledgments
- References
- 2. Reproductive genetics
- Genetic basis of disease
- Building blocks of genetics
- Genetic pathology
- Perinatal genetics
- Genetics of reproductive malignancies
- Cancer genome sequencing
- Ethical considerations of genetic diagnosis
- Key references
- References
- Suggested readings
- 3. Reproductive anatomy
- External genitalia
- Clinical correlations
- Internal genitalia
- Clinical correlations
- Clinical correlations
- Clinical correlations
- Clinical correlations
- Clinical correlations
- Vascular system of the pelvis
- Clinical correlations
- Lymphatic system
- Clinical correlations
- Innervation of the pelvis
- Clinical correlations
- Diaphragms and ligaments
- Clinical correlations
- Nongenital pelvic organs
- Clinical correlations
- Other structures
- Clinical correlations
- References
- Suggested readings
- 4. Reproductive endocrinology
- The hypothalamus and GnRH
- The anterior pituitary gland and the gonadotropins
- The ovaries
- Communication within the hypothalamic-pituitary-ovarian endocrine axis
- The menstrual cycle
- The menstrual cycle and the endometrium
- The menstrual cycle and the cervical glands
- Assay evaluation
- References
- Suggested readings
- 5. Evidence-based medicine and clinical epidemiology
- Introduction to evidence-based medicine
- Traditional clinical study design
- Comparative effectiveness research
- Health services research
- New horizons: Value in health care
- Key references
- References
- Suggested readings
- 6. Medical-legal risk management
- Historical perspective
- Reproductive medicine and the courts
- Practical insight
- Cap strategy
- Communication
- Anticipation
- Preparation
- Conclusion
- References
- Suggested readings
- Part II. Comprehensive Evaluation of the Women
- 7. History, physical examination, and preventive health care
- Direct observations before speaking to the patient (nonverbal clues)
- Essence of the gynecologic history
- Components of the physical examination
- Advocacy, screening, interventions, and referral
- Special populations
- References
- Suggested readings
- 8. Interaction of medical diseases and female physiology
- Pulmonary disease
- Gastrointestinal disease
- Hematologic and thrombotic diseases
- Central nervous system disease
- Mental health issues
- Cancer
- Summary
- Key references
- References
- 9. Additional considerations in gynecologic care
- Depression
- Eating disorders
- Obesity
- Anxiety disorders, obsessive-compulsive disorder, and posttraumatic stress disorder
- Psychotropic medications and oral contraceptives
- Substance use disorders
- “Difficult” patients and challenging clinical encounters
- Sexual function and dysfunction
- Lesbian, bisexual, and transgender health care
- Rape, sexual assault, and intimate partner violence
- Grief and loss
- Death and dying
- Key references
- References
- Suggested readings
- 10. Endoscopy in minimally invasive gynecologic surgery
- Introduction
- Preoperative decision making
- Hysteroscopy
- Gynecologic laparoscopy
- Hand-assisted laparoscopy
- Adnexal pathology
- Sterilization
- Pelvic inflammatory disease
- Oncology
- Pelvic prolapse
- Complications of laparoscopy
- Specimen removal
- How we learn: The role of endoscopic simulation
- Gynecologic surgery: The triple aim
- References
- Suggested readings
- Part III. General Gynecology
- 11. Congenital abnormalities of the female reproductive tract
- Ambiguous genitalia
- Müllerian anomalies
- References
- Suggested readings
- 12. Pediatric and adolescent gynecology
- Gynecologic visit and examination of a child
- Accidental genital trauma
- References
- Suggested readings
- 13. Contraception and abortion
- Contraception overview
- Contraceptive counseling
- Contraceptive effectiveness
- Emergency contraception
- Other contraceptive concerns
- Breastfeeding
- Induced abortion
- Methods of abortion
- References
- Suggested readings
- 14. Menopause and care of the mature woman
- Premature ovarian insufficiency
- Menopausal transition (perimenopause)
- Effects of menopause on various organ systems
- Degenerative arthritis
- Cardiovascular effects
- Cancer risks in postmenopausal women
- Disease prevention after menopause
- Alternative therapies for menopause
- Key references
- References
- Suggested readings
- 15. Breast diseases
- Anatomy/embryology
- Congenital developmental breast abnormalities
- Breast carcinoma
- Epidemiology and risks for breast cancer
- Demographic associations
- Estrogen-related exposure risks
- Lifestyle and dietary risk factors
- Breast history and breast characteristics
- Inherited and familial risks
- Radiation exposure
- Risk assessment and prevention
- Chemoprophylaxis and chemotherapeutic risk reduction
- Detection and diagnosis
- Ductal carcinoma in situ
- Lobular carcinoma in situ
- Infiltrating or invasive ductal carcinoma
- Infiltrating lobular carcinoma
- Inflammatory breast cancer
- Paget disease
- Genomic profiling
- Management
- Breast cancer during pregnancy
- Surveillance
- Key references
- References
- Suggested readings
- 16. Early and recurrent pregnancy loss
- Epidemiology
- Recurrent pregnancy loss evaluation
- Etiology
- Chromosomal
- Uterine anomalies
- Endocrine factors
- Immunologic factors
- Inherited thrombophilia
- Infections
- Environmental factors
- Male factors
- Unexplained recurrent pregnancy loss
- Pregnancy loss diagnostic evaluation
- Pregnancy loss diagnosis
- Bleeding in early pregnancy
- Management of early pregnancy loss
- Acknowledgment
- Key references
- References
- 17. Ectopic pregnancy
- Epidemiology
- Mortality
- Etiology
- Sites of ectopic pregnancy
- Histopathology
- Symptoms
- Signs
- Management
- Prognosis for subsequent fertility
- References
- Suggested readings
- 18. Benign gynecologic lesions
- Introduction
- Vulva
- Dermatologic diseases
- Vagina
- Cervix
- Uterus
- Adenomyosis
- Oviduct
- Ovary
- Key references
- References
- Suggested readings
- 19. Endometriosis
- Endometriosis: Overview
- Monitoring the course of disease: Are there markers?
- Treatment
- Endometriosis at other sites
- Extra pelvic endometriosis
- Key references
- References
- Suggested readings
- 20. Pelvic organ prolapse, abdominal hernias, and inguinal hernias
- Abdominal wall hernias
- Pelvic organ prolapse
- Rectal prolapse
- Conclusion
- Key references
- References
- Suggested readings
- 21. Lower urinary tract function and disorders
- Physiology of micturition
- Diagnostic procedures
- Lower urinary tract pain: Acute bacterial cystitis, bladder pain syndrome/interstitial cystitis, urethral diverticulum
- Urinary incontinence
- Urgency urinary incontinence/overactive bladder
- Key references
- References
- Suggested readings
- 22. Anal incontinence
- Epidemiology of incontinence
- Rectovaginal fistulas
- References
- Suggested readings
- 23. Genital tract infections
- Infections of the vulva
- Vaginitis
- Toxic shock syndrome
- Cervicitis
- Endometritis
- Pelvic inflammatory disease
- Actinomyces infection
- Tuberculosis
- References
- 24. Preoperative counseling and management
- Preoperative history
- Physical examination
- Laboratory and preoperative diagnostic procedures
- Patient education and informed consent
- Preoperative preparation
- Consultation with anesthesiologist
- Perioperative management
- Reducing postoperative complications
- Chronic anticoagulation and bleeding disorders
- Summary
- Key references
- References
- 25. Perioperative management of complications
- Postoperative fever
- Management of falling hemoglobin
- Respiratory complications
- Cardiovascular problems
- Urinary tract problems
- Gastrointestinal complications
- Wound complications
- Operative site complications
- Psychological sequelae
- Discharge instructions and postoperative visits
- Appendix A
- Appendix B
- Appendix C
- Naloxone per naloxone IV (NARCAN) administration policy
- Transition from IV to PO
- Breakthrough or procedural pain
- Oversedation
- Key references
- References
- Suggested readings
- 26. Abnormal uterine bleeding
- Causes of abnormal uterine bleeding
- Diagnostic approach
- Treatment of abnormal uterine bleeding
- Management of acute bleeding
- Key references
- References
- Suggested readings
- Part IV. Gynecologic Oncology
- 27. Molecular oncology in gynecologic cancer
- The immunologic response
- Molecular oncology
- Gynecologic malignancies
- Conclusion
- Key references
- References
- 28. Principles of radiation therapy and chemotherapy in gynecologic cancer
- Radiation therapy
- Chemotherapy
- References
- Suggested readings
- 29. Intraepithelial neoplasia of the lower genital tract (cervix, vagina, vulva)
- Introduction
- Etiology: Human papillomavirus
- Risk factors
- Primary prevention: HPV vaccination
- Secondary prevention
- Colposcopy
- Treatment of cervical dysplasia
- Vulvar intraepithelial neoplasia
- Key references
- References
- 30. Neoplastic diseases of the vulva and vagina
- Premalignant and malignant lesions of the vulva
- Vulvar atypias
- Malignant conditions
- Premalignant and malignant lesions of the vagina
- Premalignant disease of the vagina
- Malignant disease of the vagina
- Tumors of the adult vagina
- Vaginal tumors of infants and children
- Key references
- References
- Suggested readings
- 31. Malignant diseases of the cervix
- Histologic types
- Carcinoma of the cervix
- Recurrence
- References
- Suggested readings
- 32. Malignant diseases of the uterus
- Epidemiology
- Endometrial hyperplasia
- Endometrial carcinoma
- Sarcomas
- References
- Suggested readings
- 33. Malignant diseases of the ovary, fallopian tube, and peritoneum
- Familial ovarian cancer
- Classification of ovarian neoplasms
- Epithelial ovarian neoplasms
- Adnexal mass and ovarian cancer
- Rare epithelial ovarian cancer subtypes
- Small cell carcinoma
- Germ cell tumors
- Gonadoblastoma (germ cell sex cord–stromal tumor)
- Sex cord–stromal tumors
- Lipid (lipoid) tumor
- Metastatic ovarian tumors
- References
- Suggested readings
- 34. Gestational trophoblastic disease
- Hydatidiform mole
- Gestational trophoblastic neoplasia
- References
- Suggested readings
- Part V. Reproductive Endocrinology and Infertility
- 35. Primary and secondary dysmenorrhea, premenstrual syndrome, and premenstrual dysphoric disorder
- Dysmenorrhea
- Incidence and epidemiology
- Primary dysmenorrhea
- Secondary dysmenorrhea: Causes and management
- Other structural abnormalities of the reproductive tract
- Congenital obstructive anomalies
- Nongynecologic causes for pelvic pain
- Premenstrual syndrome and premenstrual dysphoric disorder
- Key references
- References
- Suggested readings
- 36. Primary and secondary amenorrhea and precocious puberty
- Primary and seconday amenorrhea
- Physiology leading up to menarche
- Primary amenorrhea
- Secondary amenorrhea
- Precocious puberty
- References
- Suggested readings
- 37. Hyperprolactinemia: Evaluation and management
- Physiology
- Causes of hyperprolactinemia
- Diagnostic techniques
- Treatment
- References
- Suggested readings
- 38. Androgen excess in women
- Physiology of androgens in women
- Causes of androgen excess
- The diagnostic approach for women with androgen excess
- Treatment of androgen excess
- References
- Suggested readings
- 39. Polycystic ovary syndrome
- Polycystic ovary syndrome: Definition
- Ovarian morphology
- The diagnosis in adolescence
- Menstrual irregularity
- Androgen excess or hyperandrogenism
- Characteristic endocrine findings in polycystic ovary syndrome
- Insulin resistance
- Antimüllerian hormone in PCOS
- Pathophysiologic considerations
- Weight gain/obesity and metabolic syndrome
- Diabetes
- Quality-of-life issues
- Cardiovascular concerns
- Cancers in polycystic ovary syndrome
- Ovarian aging: Polycystic ovary syndrome and menopause
- Isolated polycystic ovaries
- Treatment of polycystic ovary syndrome
- Treatment of subfertility in polycystic ovary syndrome
- Metabolic and weight concerns
- Key references
- References
- Suggested readings
- 40. Infertility
- Infertility and natural conception
- Incidence of subfertility and infertility
- Infertility and age
- Causes of infertility
- Diagnostic evaluation
- Prognosis of various diagnoses uncovered by the infertility investigation
- Treatment of various causes of infertility
- Pregnancy outcomes in women treated for infertility
- Counseling and emotional support
- References
- Suggested readings
- 41. In vitro fertilization
- Specific indications for in vitro fertilization
- In vitro fertilization procedure
- Risks of in vitro fertilization
- Future developments
- References
- Suggested readings
- Index
- Edition: 8
- Published: May 8, 2021
- Imprint: Elsevier
- No. of pages: 976
- Language: English
- Hardback ISBN: 9780323653992
- eBook ISBN: 9780323790789
FV
Fidel A. Valea
Fidel A. Valea is Director of Gynecologic Oncology at Northwell Health Cancer Institute, New Hyde Park, NY.
Affiliations and expertise
Director of Gynecologic Oncology, Northwell Health Cancer Institute, New Hyde Park, NY, USADG
David M. Gershenson
Affiliations and expertise
Distinguished Professor in Ovarian Cancer Research, Director of Minimally Invasive Surgical Research & Education, Department of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030GL
Gretchen M Lentz
Affiliations and expertise
Associate Professor and Director, Women’s Health; Associate Director, Women’s Health Care Center, Roosevelt; Department of Obstetrics and Gynecology, University of Washington, Seattle, WA, USARL
Rogerio A. Lobo
Dr. Lobo, formerly Rappleye Professor and Chair of the Department of Obstetrics and Gynecology, and Director of the Center for Reproductive Sciences, Columbia University, has done extensive research in various areas of reproductive endocrinology and infertility including estrogen metabolism and menopause. Dr. Lobo has a primary interest in hyperandrogenic disorders and polycystic ovary syndrome. He frequently serves as editor for peer-review journals and has authored over 300 articles and 16 books.
Affiliations and expertise
Department of Obstetrics and Gynecology, Columbia University College of Physicians & Surgeons, Columbia Presbyterian Medical Center, New York, NY Columbia University, New York, U.S.A.Read Comprehensive Gynecology on ScienceDirect