Commemorative Issue: 15 years of the Sleep Medicine Clinics Part 1: Sleep and Sleep Disorders, An Issue of Sleep Medicine Clinics

Cover image

Title page

Table of Contents

Copyright

Forthcoming Issues

Contributors

Preface

Sleep, Health, and Society

Key points

Conceptualizing sleep in a social context

Conceptualizing downstream consequences

Conceptualizing upstream influences: social-ecological models

Population prevalence of sleep duration and sleep disturbances

Sleep effects on health and longevity

Beliefs and attitudes about sleep

Gender and age impacts sleep in the population

Race, ethnicity, and culture associated with sleep

Employment, neighborhood, and socioeconomics

Influences of home, family, and school environment

Technology in and out of the bedroom

Globalization and 24/7 society

Public safety and public policy

Important limitations of the existing literature

Future research directions

Clinics care points

Disclosure

Neurobiology of Circadian Rhythm Regulation

Key points

Identification of the suprachiasmatic nucleus circadian pacemaker

Suprachiasmatic nucleus: a network of clock cells

Molecular basis of the suprachiasmatic nucleus circadian pacemaker

Functional architecture of the suprachiasmatic nucleus

Light input to the suprachiasmatic nucleus: the retinohypothalamic tract

Other functional inputs to the suprachiasmatic nucleus

Suprachiasmatic nucleus output pathways

Multioscillator nature of the circadian system

The circadian timing system in health and disease

Summary

Clinics care points

Sleep-Wake Neurochemistry

Key points

Introduction

Disclosure

Sleep in Normal Aging

Key points

Introduction

Age-related changes in sleep

Age-related changes in circadian rhythms

Sleep-related hormones, aging, and sleep

Risk factors for sleep disturbances in older adults

Summary

Clinics care points

Epidemiology of Insomnia: Prevalence, Course, Risk Factors, and Public Health Burden

Key points

Introduction

Nature of insomnia and updated diagnostic criteria

Prevalence and correlates of insomnia

Incidence and risk factors

Course of insomnia: persistence, remission, relapse

Consequences and burden of insomnia

Economic burden of insomnia

Community/public health education and prevention of insomnia

Key points and suggestions for future epidemiologic studies

Disclosure

The Effects of Insomnia and Sleep Loss on Cardiovascular Disease

Key points

Introduction

Sleep and health

Sleep and its effects on immunity and metabolic activity

Sleep loss, insomnia, and diabetes

Sleep and hypertension

Sleep and cardiovascular disease

Summary

Sleep and Cognition: A Narrative Review Focused on Older Adults

Key points

Introduction

Sleep and cognition in normal-sleeping older adults without dementia

Sleep and cognition in older adults with insomnia

Sleep and cognition in older adults with sleep-disordered breathing

Unifying theories and mechanisms

Summary and future directions

Clinics care points

Sleep in Hospitalized Older Adults

Key points

Introduction

Sleep loss in older adults

Health effects of sleep loss for hospitalized older adults

Barriers to proper sleep for hospitalized older adults

Prevalence of sleep disorders among hospitalized older adults

Interventions to improve sleep in hospitalized adults

Clinics care points

Summary

Insomnia in the Older Adult

Key points

Introduction

Comparative effectiveness of cognitive behavioral therapy for insomnia and medications

Summary

Circadian Rhythm Sleep–Wake Disorders in Older Adults

Key points

Introduction

Summary

Disclosure

Sleep Deprivation and Circadian Disruption Stress, Allostasis, and Allostatic Load

Key points

Introduction

Allostasis and allostatic overload

Circadian disruption and allostatic load and overload

Metabolic and hormonal responses to sleep deprivation and circadian disruption

Sleep deprivation and circadian disruption in mood disorders

Neural responses to sleep deprivation

Integration and summary

Sleep and Athletic Performance: Impacts on Physical Performance, Mental Performance, Injury Risk and Recovery, and Mental Health: An Update

Key points

Introduction

Epidemiology of sleep disturbances in athletes

Impact of sleep on physical performance

Impact of sleep on injury risk and recovery

Impact of sleep on mental and cognitive performance

Impact of sleep on mental health

Interventions at the team level

Summary and future directions

Clinics care points

Menstrual Cycle Effects on Sleep

Key points

Introduction

Definitions and menstrual cycle physiology

Sleep and circadian rhythms across the menstrual cycle

Sleep and ovarian dysfunction and androgen excess (polycystic ovary syndrome)

Sleep and premenstrual syndrome

Sleep and dysmenorrhea

Sleep and hormonal contraceptives

Impact of sleep on reproductive function

Disclosure statement

Parasomnias and Sleep-Related Movement Disorders in Older Adults

Key points

Sleep paralysis

Disorders of arousals

Rem sleep behavior disorder

Parasomnia overlap disorder

Anti-IgLON5 disease

Restless legs syndrome

Periodic limb movements in sleep

Disclosure

Neurodegenerative Disorders and Sleep

Key points

Introduction

Parkinson disease and other synucleinopathies

Alzheimer dementia and other tauopathies

Progressive supranuclear palsy

Clinics care points