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Elsevier

Cold-Adapted Enzymes

Biochemistry and Biotechnology

  • 1st Edition - May 1, 2027
  • Latest edition
  • Editors: Diego Gomez-Casati, Natael Maximiliano Wayllace
  • Language: English

Cold-Adapted Enzymes: Biochemistry and Biotechnology provides a cutting-edge investigation into the molecular mechanisms, structural dynamics, and regulatory pathways of enzy… Read more

Description

Cold-Adapted Enzymes: Biochemistry and Biotechnology provides a cutting-edge investigation into the molecular mechanisms, structural dynamics, and regulatory pathways of enzymes adapted to cold environments.

Beyond classical microbiology, the book explores cold adaptation from psychrophilic bacteria and Antarctic fungi to microalgae, plants, and mammalian cell physiology. It provides biochemistry insights into carbohydrate (amylases, glucoamylases) and lipid metabolism, proteases, and redox enzymes, alongside the roles of molecular chaperones and prokaryotic proteomics. A key highlight is its focus on next-generation biotechnology, featuring AI-driven protein design, advanced computational modeling, and structural bioinformatics. Bridging foundational science with market reality, the volume explores applications from organic waste valorization to industrial biocatalysis, analyzing the global patent landscape and commercial players.

As the latest volume in the Foundations and Frontiers of Enzymology series, this book is an indispensable reference for researchers across biochemistry, biotechnology, structural biology, and microbiology.

Key features

  • Covers the molecular mechanisms developed by enzymes to improve their stability and compensate for the effects of cold exposure
  • Studies the structure and biochemical properties of cold-adapted enzymes
  • Explores current and potential applications of cold-adapted enzymes in different types of industries

Readership

Researchers in biochemistry, enzymology, biotechnology, molecular evolution, structural biology and microbiology Students in related areas

Table of contents

1. Structural and functional properties of cold-adapted enzymes.

2. Structural features of cold-adapted enzymes

3. Stability of proteins in cold environments

4. Molecular mechanisms of cold-adapted enzymes

5. Enzyme evolution in cold environments

6. Diversity of cold-adapted enzymes

7. Molecular adaptations of psychrophilic enzymes

8. Bacterial cold-adapted enzymes

9. Cold-adapted enzymes from Marine bacterium

10. Cold-adapted enzymes in carbohydrate metabolism

11. Cold-adapted proteases

12. Cold-adapted metalloproteases

13. Cold-adapted enzymes in lipid metabolism

14. Cold-adapted amylases

15. Cold-adapted redox enzymes

16. Cold-adapted dehydrogenases

17. Cold-adapted enzymes from Antarctic organisms

18. Biotechnological applications of cold-adapted enzymes

19. Recombinant expression of cold-adapted enzymes

20. Protein engineering of cold-adapted enzymes

21. Computational approaches to study the cold adaptation of enzymes

22. Computational engineering of cold-adapted enzymes

23. Biodiversity of physcrophilic bacteria

24. New cold-adapted enzymes and their applications

Product details

  • Edition: 1
  • Latest edition
  • Published: May 1, 2027
  • Language: English

About the editors

DG

Diego Gomez-Casati

Dr. Diego Gomez-Casati is a senior academic and research scientist at the Centre for Photosynthetic and Biochemical Studies and Professor of Chemical Biology at the National University of Rosario, Argentina. He is PI of the Plant and Algae Molecular Biology and Biotechnology Laboratory and Vice-Director. Dr. Gomez Casati has a PhD in Biochemistry from the University of Buenos Aires. He was a visiting scientist at California State University, Fullerton, USA, Laboratoire Microbiologie Cellulaire et Moleculaire et Pathogenicite, Centre National de la Recherche Scientifique (CNRS), Université Bordeaux-2 and Pontificia Universidad Católica de Chile. He was also Professor of Plant Biotechnology at the National University of San Martín (UNSAM). Dr. Gomez-Casati’s research interests include the study of the structure, function and regulation of polysaccharide metabolism enzymes and their biotechnological applications. He has published over 85 research papers, reviews and book chapters, most related to the biochemical characterization of enzymes of energy metabolism.
Affiliations and expertise
Senior academic and research scientist, Centre for Photosynthetic and Biochemical Studies. Santa Fe, Argentina

NW

Natael Maximiliano Wayllace

Dr. Natael Maximiliano Wayllace is a Postdoctoral Researcher at the Center for Photosynthetic and Biochemical Studies (CEFOBI-CONICET), National University of Rosario, Argentina. He obtained his PhD in Biological Sciences in 2024, where he discovered and characterized novel microbial enzymes, with a particular focus on extremophilic systems, including cold-adapted and thermostable glucoamylases. His research combines biochemical and kinetic characterization with computational modeling to investigate enzyme adaptation mechanisms and structure–function relationships. Dr. Wayllace has authored several peer-reviewed publications on microbial enzymes, including studies on the structural and functional properties of cold-active glucoamylases. He has extensive university teaching experience and has supervised undergraduate students in biotechnology. His expertise in cold-adapted enzymes, enzymology, and protein engineering, is complemented by his academic contributions as reviewer and thesis examiner.
Affiliations and expertise
Center for Photosynthetic and Biochemical Studies, National Council for Scientific and Technical Research (CEFOBI-CONICET). School of Biochemistry and Pharmacy, National University of Rosario (UNR), Argentina