Clinical Psychiatry, An Issue of Medical Clinics of North America

Cover image

Title page

Table of Contents

Copyright

CME Accreditation Page

Forthcoming Issues

Contributors

Foreword

Preface

The Role of Inflammation in the Pathophysiology of Depression and Suicidal Behavior: Implications for Treatment

Key points

Introduction: Pathobiology of depression and suicidal behavior

Characteristics and origins of inflammation in depression

Characteristics and origins of inflammation in suicide behavior development

Therapeutic insights

Summary

Conflicts of interest

Funding

Clinics care points

Fire and Darkness: On the Assessment and Management of Bipolar Disorder

Key points

Introduction

Impact

Bipolar subtypes and course of illness

Assessment

Management

Populations of special interest

Follow-up and monitoring with measurement-based care

Summary

Clinics care points

Schizophrenia: One Name, Many Different Manifestations

Key points

Introduction

Diagnosis

Etiology

Neurobiology of schizophrenia

Treatment

Summary

Clinics care points

Microbiome in Anxiety and Other Psychiatric Disorders

Key points

Introduction

Discussion

Depression and the microbiome

Anxiety and the microbiome

Obsessive-compulsive disorder and the microbiome

Pandas/Pans and the microbiome

Summary

Post-traumatic Stress Disorder

Key points

Post-traumatic stress disorder

Clinics care points

From Mouse to Man: N-Methyl-d-Aspartic Acid Receptor Activation as a Promising Pharmacotherapeutic Strategy for Autism Spectrum Disorders

Key points

Introduction

Summary

Clinics care points

Suicide: An Overview for Clinicians

Key points

Definitions

Epidemiology

Suicidal behavior in psychiatric disorders

Suicidal behavior in medical and neurologic disorders

Demographic factors

Psychosocial factors

Neurobiology

The role of primary care physicians

Management of suicidal individuals

Clinics care points

Psychiatric Issues Among Health Professionals

Key points

Introduction

The impact of COVID-19 in health professionals

Difficulties in seeking appropriate help and its consequences

Specialized mental health treatment resources for health professionals

Summary

Clinics care points

Overall goal of Cognitive-Behavioral Therapy in Major Psychiatric Disorders and Suicidality: A Narrative Review

Key points

Introduction

Cognitive-behavioral therapy on unipolar/bipolar affective disorder

Cognitive-behavioral therapy on anxiety disorders and posttraumatic stress disorder

Cognitive-behavioral therapy for body dysmorphic disorder

Cognitive-behavioral therapy on insomnia

Cognitive-behavioral therapy for suicidality

Internet-based approaches

Summary

Clinics care points

Funding

Depression and Suicidal Behavior in Adolescents

Key points

Introduction

Gender and age differences

Risk factors for adolescent depression and suicidality

Nonsuicidal self-injury

Adverse childhood experiences and suicidality

Substance use and depression and suicidality in adolescence

Protective factors and resilience in adolescent depression and suicidality

Assessment for adolescent depression and suicidality

Adolescent depression and the COVID-19 pandemic

Social media’s influence on adolescent mental health

Recommendations

Treatment options

Barriers to care

Summary

Clinics care points

Frailty: A Multidimensional Biopsychosocial Syndrome

Key points

Introduction

Definitions

Epidemiology

Diagnosis and assessment

Predictors, pathogenesis, and course

Treatment and prevention

Unresolved issues

Summary

Clinics care points

Disclosure