
Clinical Cases in Ocular Oncology
Differential Diagnosis and Management
- 1st Edition - June 21, 2024
- Imprint: Elsevier
- Editors: Aparna Ramasubramanian, Carol L. Shields
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 2 0 4 9 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 2 0 7 4 - 9
The complex area of ocular oncology requires adaptable approaches to treatment depending on the type and anatomical region of the tumor, tumor characteristics, the patient’s age,… Read more

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Request a sales quoteThe complex area of ocular oncology requires adaptable approaches to treatment depending on the type and anatomical region of the tumor, tumor characteristics, the patient’s age, co-morbidities, and response to first-line treatment. Through the use of practical, case-based content, Clinical Cases in Ocular Oncology helps you familiarize yourself with clinical decision making in this challenging field, providing expert guidance on diagnosis, management, and treatment planning.
- Includes 66 cases covering a range of patient presentations and scenarios that mirror day-to-day practice.
- Covers a variety of ophthalmic tumors, including intraocular melanoma, lymphoma of the eye, retinoblastoma, conjunctiva, choroidal melanoma, squamous cell carcinoma, lacrimal gland tumors, and tumors of the eyelid.
- Presents each case in an easy-to-read, templated format covering an overview of patient history, questions to ask, assessment, differential diagnosis, multimodal testing and results, management, follow-up care, and key points.
- Provides outstanding visual guidance with numerous pathology slides and clinical photos, as well as current diagnostic imaging modalities such as optical coherence tomography (OCT), ultrasound, fluorescein angiography (FA), and indocyanine green angiography (ICG).
- Features diagnostic and management algorithms that assist in differential diagnosis and decision making for even the most complex cases.
- An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish up to 6 weeks following the publication date.
Ophthalmologists; ophthalmology residents
- Cover image
- Title page
- Copyright
- Dedication
- Dedication
- Contributors
- Preface
- Contents
- Section 1 Eyelid/Orbital Tumors
- CHAPTER 1 Eyelid Squamous Cell Carcinoma
- Chronic Unilateral Blepharoconjunctivitis in a 90-Year-Old
- Acknowledgment
- CHAPTER 2 Eyelid Basal Cell Carcinoma
- Multiple Eyelid Lesions in a 43-Year-Old White Female
- CHAPTER 3 Eyelid Melanoma
- Eyelid Malignant Melanoma in a 47-Year-Old Female of Hispanic Origin
- CHAPTER 4 Orbit Infantile Hemangioma
- Increased Swelling of the Eyelid in a 2-Month-Old Child
- CHAPTER 5 Orbital Dermoid Cyst
- Painless, Slow-Growing, Periorbital Mass in a 3-Year-Old Child
- CHAPTER 6 Orbit Lymphoma
- Tearing and Eye Swelling OS for 4 Months in a 54-Year-Old Male
- CHAPTER 7 Orbit Cavernous Venous Malformation
- Right Lower Eyelid Swelling, Inferior Orbital Mass, Proptosis and Globe Displacement in a 58-Year-Old Female
- Suggested Reading
- CHAPTER 8 Orbit Lymphangioma
- Painful Proptosis in a 5-Year-Old Child
- CHAPTER 9 Orbit Rhabdomyosarcoma
- Orbital Rhabdomyosarcoma: Assessment of Treatment Response
- References
- CHAPTER 10 Orbit Lacrimal Pleomorphic Adenoma
- Progressive Unilateral Ptosis in an 11-Year-Old Child
- CHAPTER 11 Orbit Metastatic Tumor
- Right Eye Proptosis and Epiphora in a 4-Year-Old Child for 1 Month
- CHAPTER 12 Orbit Lacrimal Adenoid Cystic Carcinoma
- Proptosis and Pain in a 32-Year-Old Female
- CHAPTER 13 Optic Nerve Pilocytic Astrocytoma (Glioma)
- 11-Month Old Male With Multiple Café Au Lait Spots
- CHAPTER 14 Optic Nerve Sheath Meningioma
- Decreased Unilateral Visual Acuity in a 12-Year-Old Female
- Section 2 Conjunctival Tumors
- CHAPTER 15 Conjunctival Lipodermoid
- Conjunctival Mass in a 12-Year-Old Female
- CHAPTER 16 Conjunctival Nevus
- 65-Year-Old With Pigmented Conjunctival Lesion
- CHAPTER 17 Conjunctival Primary Acquired Melanosis Localized
- Unilateral Pigmented Conjunctival Lesion Involving 2 Clock-Hours in a 58-Year-Old Female
- CHAPTER 18 Conjunctival Primary Acquired Melanosis Diffuse
- Diffuse Unilateral Conjunctival Pigmentation in a 76-Year-Old White Female
- CHAPTER 19 Conjunctival Melanoma—Localized
- Melanotic Conjunctival Lesion in a 65-Year-Old White Male
- CHAPTER 20 Conjunctival Melanoma Diffuse
- Multiple Conjunctival Lesions in a 48-Year-Old Black Female
- CHAPTER 21 Conjunctival Melanoma With Lymph Node Involvement
- New Pigmented Lesion in Bulbar Conjunctiva
- CHAPTER 22 Conjunctival Squamous Cell Carcinoma
- Conjunctival Mass in a 59-Year-Old Male Postsurgery
- CHAPTER 23 Conjunctival Squamous Cell Carcinoma Recurrent
- Vascular Elevated Conjunctival Mass in a 68-Year-Old Male
- CHAPTER 24 Conjunctiva Lymphoma
- Fleshy Pinkish Mass on Right Eye Conjunctiva in a 38-Year-Old Male
- Section 3 Iris and Ciliary Body Tumors
- CHAPTER 25 Iris Juvenile Xanthogranuloma
- White Area on the Right Iris in a 2-Month-Old Female
- CHAPTER 26 Iris Nevus
- A Pigmented Iris Lesion in a 59-Year-Old Female
- Reference
- CHAPTER 27 Iris Melanoma Nodular
- A Growing Pigmented Iris Lesion in a 44-Year-Old Healthy Patient
- CHAPTER 28 Iris Melanoma Diffuse
- Iris Neovascularization and Increased Intraocular Pressure in a 64-Year-Old Male
- CHAPTER 29 Iris Pigment Epithelial Cyst
- Asymptomatic Iris Lesion With Progression in Size
- CHAPTER 30 Ciliary Body Medulloepithelioma
- Leukocoria and Decreased Visual Acuity in a 3-Year-Old Female
- CHAPTER 31 Ciliary Body Adenoma (Epithelioma)
- Retrolental Mass in a 41-Year-Old Female
- Section 4 Uveal Pigmented Tumors
- CHAPTER 32 Choroid Nevus
- Pigmented Choroidal Lesion in the Right Eye (OD) of a 67-Year-Old Male
- CHAPTER 33 Choroid Nevus with Subretinal Fluid
- Decreased Visual Acuity and Floaters in a 61-Year-Old Female
- CHAPTER 34 Choroid Nevus With Pigment Epithelial Detachment
- Decreased Visual Acuity in a 58-Year-Old Female
- CHAPTER 35 Choroid Melanoma—Small
- A Pigmented Choroidal Lesion With Suspicious Features
- References
- CHAPTER 36 Choroid Melanoma—Medium
- Ongoing Photopsia in a 49-Year-Old Woman
- CHAPTER 37 Choroid Melanoma—Large
- Painless Visual Field Deficit and Photopsias in a 72-Year-Old Male
- CHAPTER 38 Choroid Melanoma—Extrascleral Extension
- Choroidal Lesion and Corectopia in a 68-Year-Old Female
- CHAPTER 39 Choroid Melanoma—Isolated Liver Metastasis
- Incidental Finding on Routine Eye Screening
- CHAPTER 40 Choroid Melanoma—Diffuse Metastasis
- Retinal Detachment and 1 Month of Decreased Visual Acuity in a 64-Year-Old White Female
- Treatment Options for Choroid Melanoma With Diffuse Liver Metastasis
- CHAPTER 41 Choroid Melanoma—Radiation Retinopathy
- New Cotton Wool Spots and Decreased Visual Acuity Post–Plaque Radiotherapy
- Section 5 Retinoblastoma
- CHAPTER 42 Retinoma
- 11-Year-Old Male With Retinal Mass
- Key Points
- CHAPTER 43 Retinoblastoma—Unilateral Medium Grade
- Leukocoria With Exotropia in a 2-Year-Old Female Child
- CHAPTER 44 Retinoblastoma—Unilateral High Grade
- Protrusion of the Eye in a 3.5-Year-Old Female
- CHAPTER 45 Retinoblastoma—Unilateral With High-Risk Features
- Right Eye Leukocoria in a 4-Year-Old Child
- Suggested Reading
- CHAPTER 46 Retinoblastoma—Vitreous Seeding
- Unilateral Leukocoria in a 17-Month-Old Female
- References
- CHAPTER 47 Retinoblastoma—Bilateral Medium Grade
- Strabismus in a 9-Month-Old Infant
- CHAPTER 48 Retinoblastoma—Bilateral Advanced
- Strabismus in an 11-Month-Old Child
- CHAPTER 49 Retinoblastoma—Family History
- Third-Generation Child With Bilateral Retinoblastoma
- CHAPTER 50 Retinoblastoma—Orbital Involvement
- Leukocoria and Decreased Visual Acuity in a 1-Year-Old Child
- Reference
- CHAPTER 51 Retinoblastoma—Metastatic
- Leukocoria, Neovascular Glaucoma, and Subconjunctival Mass in a 20-Month-Old Male
- CHAPTER 52 Retinoblastoma—Second Malignancy
- Osteosarcoma Secondary to RB1 Germline Mutation
- CHAPTER 53 Pinealoblastoma
- 7-Month-Old Child With Bilateral Retinoblastoma and Pinealoblastoma
- Section 6 Nonpigmented Posterior Segment Tumors
- CHAPTER 54 Choroid Metastasis—Isolated
- Decreased Visual Acuity in a Woman With a History of Cancer
- CHAPTER 55 Choroid Metastasis—Multifocal
- Painless, Progressive Decreased Vision in the Right Eye of a 69-Year-Old Female With a Choroidal Lesion
- CHAPTER 56 Choroid Hemangioma Circumscribed
- Decreased Visual Acuity in a 53-Year-Old Male
- CHAPTER 57 Choroid Hemangioma Diffuse
- Decreased Visual Acuity in an 11-Year-Old Child
- CHAPTER 58 Choroid Osteoma
- Decreased Vision in a 29-Year-Old Male
- CHAPTER 59 Choroid Primary Lymphoma
- A 56-Year-Old Female Was Referred for Choroidal Infiltration of the Right Eye
- CHAPTER 60 Retina Vasoproliferative Tumor
- Decreased Vision and Floaters in a 23-Year-Old Female
- CHAPTER 61 Retina Hemangioblastoma
- Left Inferior Retinal Mass in a 16-Year-Old Male With von Hippel-Lindau Syndrome
- CHAPTER 62 Retina Astrocytoma
- Retinal Lesions in a 21-Year-Old Female
- CHAPTER 63 Retina Congenital Hypertrophy of Retinal Pigment Epithelium
- Left Retinal Lesions in a 5-Year-Old Child
- CHAPTER 64 Retinal Pigment Epithelium Adenoma/Adenocarcinoma
- Decreased Vision and Pigmented Lesion in a 52-Year-Old Female
- CHAPTER 65 Primary Vitreoretinal Lymphoma
- Chronic Floaters and Decreased Visual Acuity in a 69-Year-Old Female
- CHAPTER 66 Retina Combined Hamartoma
- Decreased Vision in a 14-Year-Old Female
- Index
- Edition: 1
- Published: June 21, 2024
- Imprint: Elsevier
- Language: English
- Paperback ISBN: 9780443120497
- eBook ISBN: 9780443120749
AR
Aparna Ramasubramanian
Affiliations and expertise
Director of Retinoblastoma & Ocular Oncology, Phoenix Children’s Hospital, Phoenix, AZCS
Carol L. Shields
Affiliations and expertise
Chief, Ocular Oncology Service, Wills Eye Hospital , Professor of Ophthalmology, Thomas Jefferson University, Philadelphia, PARead Clinical Cases in Ocular Oncology on ScienceDirect