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Clinical Arrhythmology and Electrophysiology
- 4th Edition - June 1, 2023
- Authors: Ziad Issa, John M. Miller, Douglas P. Zipes
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 8 8 1 8 2 - 1
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 8 1 8 3 - 8
Part of the renowned Braunwald family of references, Clinical Arrhythmology and Electrophysiology: A Companion to Braunwald’s Heart Disease provides today’s clinicians with clear,… Read more
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Request a sales quotePart of the renowned Braunwald family of references, Clinical Arrhythmology and Electrophysiology: A Companion to Braunwald’s Heart Disease provides today’s clinicians with clear, authoritative guidance on every aspect of the latest diagnosis and management options for patients with arrhythmias. This comprehensive reference on cardiac arrhythmias lays a solid foundation of the underlying mechanisms of cardiac electrophysiology with an emphasis on identifying, understanding, and treating individual arrhythmias. Now fully updated from cover to cover, and carefully written to provide continuity and a consistent message throughout, the 4th Edition offers unparalleled coverage of cardiac arrhythmias in an accessible and user-friendly manner.
Grounds clinical techniques in basic science for managing patients with complex arrythmia disorders.
Offers increased clinical content with complete diagnostic and management options, including the latest drug-based, device-based, and device-drug therapies.
Covers new tools and techniques for atrial transseptal and percutaneous pericardial access, new ablation energies and tools, and new ACC/HRS guidelines for bradyarrhythmias.
Contains a new chapter on stroke prevention in atrial arrhythmias.
Includes significant content updates on macro-reentrant atrial tachycardias in an era of ultra-high-resolution mapping, new mapping and ablation technologies for ventricular tachycardia, new genetic mechanisms underlying arrhythmia syndromes, and much more.
Provides access to dozens of videos depicting key mapping techniques, and fluoroscopy images illustrating techniques for electrophysiologic catheter positioning, and atrial septal puncture, as well as pericardial access, cryoablation, and left atrial appendage exclusion procedures.
Uses a consistent format throughout, showing every arrhythmia in a similar manner for quick reference.
An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
General cardiology and electrophysiology fellows, practicing cardiologists
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Foreword: Clinical Arrhythmology and Electrophysiology, 4th ed
- Preface
- Video contents
- Braunwald’s heart disease family of books
- List of Illustrations
- List of Tables
- 1. Introduction
- Purpose
- History
- Epidemiology
- Future
- References
- 2. Molecular mechanisms of cardiac electrical activity
- Ionic equilibrium
- Transmembrane potentials
- The cardiac action potential
- Excitability
- Refractoriness
- Propagation
- Excitation-contraction coupling
- References
- 3. Cardiac ion channels
- Sodium channels
- Potassium channels
- Calcium channels
- Cardiac pacemaker current (If)
- Sarcoplasmic reticulum calcium release channels (ryanodine receptor 2)
- Cardiac gap junctions
- References
- 4. Electrophysiological mechanisms of cardiac arrhythmias
- Automaticity
- Triggered activity
- Reentry
- References
- 5. Electrophysiological testing: Tools and techniques
- Indications
- Periprocedural management
- Catheterization techniques
- Signal acquisition and processing
- Intracardiac electrograms
- Baseline intervals
- Programmed electrical stimulation
- Atrial stimulation
- Ventricular stimulation
- Miscellaneous electrophysiological phenomena
- Complications of electrophysiological testing
- References
- 6. Conventional intracardiac mapping techniques
- Activation mapping
- Entrainment mapping
- Pace mapping
- References
- 7. Advanced mapping and navigation modalities
- Electroanatomical mapping
- Noncontact mapping
- Stereotaxis magnetic navigation system
- Robotic navigation system
- MediGuide navigation system
- Body surface potential mapping
- Electrocardiographic mapping
- Intracardiac echocardiography
- Computed tomography and magnetic resonance imaging
- Three-dimensional rotational angiography
- References
- 8. Ablation energy sources
- Radiofrequency ablation
- Cryoablation
- Laser energy
- Pulsed field ablation
- Ultrasound energy
- Microwave ablation
- Radioablation
- References
- 9. Sinus node dysfunction
- Anatomy and physiology of the sinus node
- Pathophysiology of sinus node dysfunction
- Clinical presentation
- Epidemiology and natural history
- Diagnostic evaluation
- Electrocardiographic features
- Electrophysiological testing
- Principles of management
- References
- 10. Atrioventricular conduction abnormalities
- Anatomy and physiology of the atrioventricular junction
- Pathophysiology of atrioventricular block
- Clinical presentation
- Natural history
- Diagnostic evaluation
- Electrocardiographic features
- Electrophysiological testing
- Principles of management
- References
- 11. Intraventricular conduction abnormalities
- Transient bundle branch block
- Chronic bundle branch block
- Electrocardiographic features
- Electrophysiological testing
- References
- 12. Focal atrial tachycardia
- Classification of atrial tachycardias
- Pathophysiology
- Epidemiology
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Mapping
- Ablation
- References
- 13. Typical atrial flutter
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Mapping
- Ablation
- References
- 14. Macroreentrant atrial tachycardia
- Pathophysiology
- Epidemiology
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Mapping
- Ablation
- References
- 15. Atrial tachyarrhythmias in adults with congenital heart disease
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Mapping
- Ablation
- References
- 16. Atrial fibrillation: Pathophysiology and epidemiology
- Classification of atrial fibrillation
- Mechanism of atrial fibrillation
- Substrate for atrial fibrillation
- Atrial remodeling in atrial fibrillation
- Role of autonomic nervous system in atrial fibrillation
- Role of the pulmonary veins in atrial fibrillation
- Genetics in atrial fibrillation
- Epidemiology
- References
- 17. Atrial fibrillation: Clinical presentation and evaluation
- Clinical presentation
- Initial evaluation
- Electrocardiographic features
- References
- 18. Atrial fibrillation: Management
- Rate control
- Pharmacologic rhythm control
- Catheter ablation of atrial fibrillation
- Surgical ablation of atrial fibrillation
- Other nonpharmacological approaches for rhythm control
- Upstream therapy
- Risk factor management
- Management of postoperative atrial fibrillation
- Catheter ablation strategies
- Circumferential antral pulmonary vein isolation
- Linear atrial ablation
- Ablation of non–pulmonary vein triggers
- Pulmonary vein denervation
- Fibrosis-guided substrate modification
- Mechanism-based approaches for ablation of atrial fibrillation
- Outcome and efficacy of catheter ablation of atrial fibrillation
- Recommendations and controversies
- Atrioventricular junction ablation
- Atrioventricular nodal modification
- References
- 19. Atrial fibrillation: Stroke prevention strategies
- Risk of thromboembolism
- Stroke risk stratification
- Bleeding risk stratification
- Prevention of systemic embolization
- Percutaneous left atrial appendage device closure
- Percutaneous left atrial appendage ligation
- Surgical left atrial appendage exclusion
- References
- 20. Inappropriate sinus tachycardia
- Anatomy and physiology of the sinus node
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrophysiological testing
- Ablation
- References
- 21. Atrioventricular nodal reentrant tachycardia
- Anatomy and physiology of the atrioventricular node
- Pathophysiology
- Epidemiology
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Ablation
- References
- 22. Typical atrioventricular bypass tracts
- Types of bypass tracts
- Types of preexcitation syndromes
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Atrial activation sequence
- Localization of the bypass tract
- Ablation
- References
- 23. Atypical bypass tracts
- “Mahaim fibers”
- “Mahaim tachycardia”
- Atypical atrioventricular and atriofascicular bypass tracts
- Nodofascicular and nodoventricular bypass tracts
- Fasciculoventricular bypass tracts
- Atrio-Hisian bypass tracts
- Permanent junctional reciprocating tachycardia
- References
- 24. Paroxysmal supraventricular tachycardias
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Practical approach to electrophysiological diagnosis of supraventricular tachycardia
- References
- 25. Wide complex tachycardias
- Clinical considerations
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- References
- 26. Ventricular arrhythmias in ischemic heart disease
- Classification of ventricular tachyarrhythmias
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Risk stratification
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Mapping
- Ablation
- References
- 27. Idiopathic focal ventricular tachycardia
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Differential diagnosis
- Principles of management
- Electrocardiographic localization of focal ventricular tachycardia
- Electrophysiological testing
- Mapping
- Ablation
- Right ventricular outflow tract arrhythmias
- Pulmonary artery arrhythmias
- Left ventricular ostium arrhythmias
- Aortic root arrhythmias
- Left ventricular summit arrhythmias
- Left ventricular papillary muscle arrhythmias
- Para-Hisian ventricular arrhythmias
- Cardiac crux arrhythmias
- Endocavitary right ventricular arrhythmias
- Focal Purkinje ventricular arrhythmias
- Intramural ventricular arrhythmias
- References
- 28. Idiopathic fascicular reentrant ventricular tachycardia
- Pathophysiology
- Epidemiology
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Mapping
- Ablation
- References
- 29. Ventricular tachycardia in nonischemic dilated cardiomyopathy
- Pathophysiology
- Epidemiology and natural history
- Initial evaluation
- Risk stratification
- Principles of management
- Electrocardiographic features
- Mapping
- Ablation
- Cardiac sarcoidosis
- Chagas cardiomyopathy
- Other inflammatory cardiomyopathies
- References
- 30. Bundle branch reentrant ventricular tachycardia
- Pathophysiology
- Epidemiology
- Clinical presentation
- Initial evaluation
- Principles of management
- Electrocardiographic features
- Electrophysiological testing
- Ablation
- Interfascicular reentrant ventricular tachycardia
- References
- 31. Epicardial ventricular tachycardia
- Electrophysiological substrate
- Electrocardiographic features
- Clinical considerations
- Navigating the pericardial space
- Transthoracic epicardial mapping
- Transthoracic epicardial ablation
- Transvenous epicardial mapping and ablation
- References
- 32. Arrhythmias in hypertrophic cardiomyopathy
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Differential diagnosis
- Risk stratification
- Principles of management
- References
- 33. Ventricular tachycardia in inherited arrhythmogenic cardiomyopathy
- Definition and classification
- Pathophysiology
- Epidemiology and natural history
- Clinical presentation
- Initial evaluation
- Differential diagnosis
- Risk stratification
- Principles of management
- Electrocardiographic features
- Electrophysiological features
- Mapping
- Ablation
- References
- 34. Ventricular arrhythmias in adults with congenital heart disease
- Pathophysiology
- Epidemiology and natural history
- Initial evaluation
- Risk stratification
- Principles of management
- Electrocardiographic features
- Mapping
- Ablation
- References
- 35. Ventricular arrhythmias in inherited channelopathies
- Long QT syndrome
- Short QT syndrome
- Catecholaminergic polymorphic ventricular tachycardia
- Brugada syndrome
- Early repolarization syndromes
- Idiopathic ventricular fibrillation
- References
- 36. Complications of catheter ablation of cardiac arrhythmias
- Local vascular complications
- Cardiac perforation
- Thromboembolism
- Air embolism
- Coronary artery injuries
- Iatrogenic cardiac arrhythmias
- Valvular damage
- Phrenic nerve injury
- Pulmonary vein stenosis
- Esophageal injury
- Radiation exposure
- References
- Index
- No. of pages: 1216
- Language: English
- Edition: 4
- Published: June 1, 2023
- Imprint: Elsevier
- Hardback ISBN: 9780323881821
- eBook ISBN: 9780323881838
ZI
Ziad Issa
Affiliations and expertise
Executive Director, Department of Cardiac Electrophysiology, Prairie Heart Institute of Illinois, Springfield, IllinoisJM
John M. Miller
Affiliations and expertise
Professor of Medicine, Indiana University School of Medicine, Director, Clinical Cardiac Electrophysiology, Indiana University Health, Indianapolis, IndianaDZ
Douglas P. Zipes
Affiliations and expertise
Distinguished Professor, Division of Cardiology and the Krannert Institute of Cardiology, Indiana University School of Medicine, Indianapolis, Indiana