
Cholesteatoma, An Issue of Otolaryngologic Clinics of North America
- 1st Edition, Volume 58-1 - November 15, 2024
- Imprint: Elsevier
- Editors: Samantha Anne, Michael Hoa
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 3 4 3 3 6 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 4 3 3 7 - 7
In this issue of Otolaryngologic Clinics, guest editors Drs. Samantha Anne and Michael Hoa bring their considerable expertise to the topic of Cholesteatoma. Top experts cover… Read more

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Request a sales quoteIn this issue of Otolaryngologic Clinics, guest editors Drs. Samantha Anne and Michael Hoa bring their considerable expertise to the topic of Cholesteatoma. Top experts cover all aspects of this condition, including the science of cholesteatoma, evaluation of cholesteatoma, principles of cholesteatoma management; complications of chronic otitis media and cholesteatoma; congenital cholesteatoma; and much more.
- Contains 15 relevant, practice-oriented topics including various techniques of management of cholesteatoma; outcomes with management of cholesteatoma; complications of surgery; recidivism and recurrence; and more.
- Provides in-depth clinical reviews on cholesteatoma, offering actionable insights for clinical practice.
- Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Otolaryngology, otorhinolaryngology, neurotology
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Forthcoming Issues
- Foreword
- Preface
- The Science of Cholesteatoma
- Key points
- Introduction
- Etiopathogenesis of acquired cholesteatoma
- Gene expression in cholesteatoma
- Recruitment and activation of the innate immune system
- Mitogenic and inflammatory signaling via growth factors
- Induction of angiogenesis via inflammatory and growth factor signaling
- Impairments and alterations in cellular and structural integrity
- Osteoclastogenesis and bone erosion
- MicroRNA regulation of gene expression
- Summary
- Clinics care points
- Evaluation of Cholesteatoma
- Key points
- Introduction
- Clinical examination
- Imaging
- Summary
- Clinics care points
- Principles of Cholesteatoma Management
- Key points
- Introduction
- Classification and staging system
- Canal wall up versus canal wall down surgery
- Mastoid obliteration
- Endoscopic ear surgery for cholesteatoma
- General management principles
- Clinics care points
- Complications of Cholesteatoma
- Key points
- Introduction
- Discussion
- Summary
- Clinics care points
- Congenital Cholesteatoma
- Key points
- Introduction
- History
- Definition
- Etiology
- Epidemiology
- Diagnosis
- Imaging
- Staging
- Management
- Summary
- Clinics care points
- Management of Cholesteatoma: Surgical Options for Disease Limited to Middle Ear/Mastoid
- Key points
- Introduction
- Overview of surgical techniques
- Assessment/imaging techniques
- Indications and contraindications/patient selection
- Discussion
- Summary
- Clinics care points
- Management of Cholesteatoma: Extension Beyond Middle Ear/Mastoid
- Key points
- Introduction
- History
- Etiology
- Presentation
- Evaluation
- Disease staging
- Discussion
- Surgical approach
- Outcomes
- Complications
- Aural rehabilitation
- Summary
- Clinics care points
- Techniques in Management of Cholesteatoma: Endoscopic Approaches
- Key points
- Introduction
- Safe endoscopic technique
- Standard technique for cholesteatoma with transcanal endoscopic ear surgery
- Other endoscopic approaches for cholesteatoma
- Instrumentation and additional techniques
- Summary
- Supplementary data
- Techniques in Management of Cholesteatoma: Modified Radical and Retrograde Mastoidectomy
- Key points
- Brief history and definitions
- Discussion
- Summary
- Clinics care points
- Supplementary data
- Techniques in Management of Cholesteatoma: Radical and Canal Wall down Mastoidectomy
- Key points
- Introduction
- History
- Definitions
- Discussion
- Summary
- Clinics care points
- Supplementary data
- Techniques in Management of Cholesteatoma: Subtotal Petrosectomy; Blind Sac Closure
- Key points
- Background
- Indications and contraindications
- Outcomes
- Technique
- Summary
- Clinics care points
- Outcomes with Management of Cholesteatoma
- Key points
- Introduction
- Mastoidectomy
- Sodium 2-mercaptoethanesulfonate
- Ossicular chain reconstruction
- Incus interposition
- Partial ossicular reconstruction prosthesis/total ossicular reconstruction prosthesis
- Type III tympanoplasty
- Overall hearing outcomes in ossicular chain reconstruction
- Endoscopic cholesteatoma outcomes
- Quality-of-life outcomes
- Congenital cholesteatoma outcomes
- Summary
- Clinics care points
- Management of Cholesteatoma: Hearing Rehabilitation
- Key points
- Introduction
- Hearing outcomes after canal wall up and canal wall down mastoidectomy
- Overview of hearing rehabilitation options
- Advanced hearing solutions: (frequency modulation systems, Bluetooth, and hearing loops frequency modulation systems)
- Summary
- Clinics care points
- Complications of Surgery: Recognition and Management
- Key points
- Introduction
- Background
- Intraoperative complication
- Acute postoperative complications
- Long-term postoperative complication
- Discussion
- Summary
- Clinics care points
- Recidivism and Recurrence
- Key points
- Introduction
- Epidemiology
- Evaluation
- Management
- Summary
- Clinics care points
- Edition: 1
- Volume: 58-1
- Published: November 15, 2024
- Imprint: Elsevier
- No. of pages: 240
- Language: English
- Hardback ISBN: 9780443343360
- eBook ISBN: 9780443343377
MH
Michael Hoa
Affiliations and expertise
Associate Professor, Medical Director, MGUH Cochlear Implant Program, Director of Research, Department of Otolaryngology-Head and Neck Surgery, Georgetown University Medical Center, Medstar Georgetown University Hospital, Washington, DC, USA