Channels, Carriers, and Pumps
An Introduction to Membrane Transport
- 1st Edition - November 12, 2012
- Author: Wilfred D. Stein
- Language: English
For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport… Read more
For students as well as researchers this book describes the exciting new advances in the molecular biology of transport proteins and integrates this information with transport kinetics, function, and regulation. Experimental data are linked with theory.
- Provides an introduction to the properties of transport proteins: channels, carriers, and pumps
- Presents up-to-date information on the structure of transport proteins and on their function and regulation
- Includes introductions to transport kinetics and to the cloning of genes that code transport proteins
- Furnishes a link between the experimental basis of the subject and theoretical model building
Cell biologists, biophysicists, physiologists, biochemists, neurobiologists, pharmacologists, and graduate students in these disciplines
Structural Basis of Movement across Cell Membranes. Simple Diffusion of Nonelectrolytes and Ions. Ion Channels across Cell Membranes. Carrier-Mediated Transport: Facilitated Diffusion. Coupling of Flows of Substrates: Antiporters and Symporters. Primary Active Transport Systems. The Regulation and Integration of Transport Systems. Appendixes: Single and Triple-Letter Codes for the Amino Acids. Fundamental Constants, Conversion Factors, and Some Useful Approximations. The Relation between the Permeability Coefficient Ps and the Half-Time t1/2 of Entry of a Permeant. Index.
- Edition: 1
- Published: November 12, 2012
- Language: English
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Wilfred D. Stein
Wilfred Stein is the author of three previous books on membrane transport, the first appearing almost fifty years ago. He has edited numerous books and written some 180 papers on various aspects of membrane transport and especially transport kinetics. These papers, especially those written together with his colleague William Lieb, defined many of the concepts used today in discussing movement across cell membranes. More recently he has turned to the study of the kinetics of drugs used in cancer therapy and in the treatment of malaria. He has taught biochemistry, biophysics and physiology at the University of Manchester and the Hebrew University of Jerusalem and also at the Weizmann Institute in Israel. He is currently Emeritus Professor of Biophysics at the Hebrew University. He is married to a librarian and has four children and nine grandchildren.
Affiliations and expertise
Silberman Institute of Life Sciences, Hebrew University, Jerusalem, IsraelRead Channels, Carriers, and Pumps on ScienceDirect