Chalcones and their Derivatives
From Synthesis to Applications
- 1st Edition - October 1, 2025
- Editors: Mohmmad Younus Wani, Salman Ahmad Khan, Hao Shao, Anish Khan
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 0 1 2 2 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 0 1 2 3 - 0
Chalcone is a highly versatile scaffold with a broad range of applications. Serving as a precursor for various organic molecules and natural flavonoids, it exhibits significa… Read more
Chalcone is a highly versatile scaffold with a broad range of applications. Serving as a precursor for various organic molecules and natural flavonoids, it exhibits significant biological activities and unique physical properties, including semiconductor behavior, non-linear optical effects, fluorescence, and electronic characteristics. Chalcones have attracted considerable research interest due to their pharmacological potential and the ease with which their biological activity and other properties can be modified through subtle structural changes along the α,β-unsaturated backbone. Beyond their medicinal value, chalcones are utilized in the food and cosmetic industries as additives, owing to their UV-protective qualities. Additionally, they serve as chemosensors and probes in analytical applications. The book Chalcones and Their Derivatives: From Synthesis to Applications explores this remarkable molecule, detailing various synthetic methods, its biological significance, and its diverse applications across multiple fields. Serving as both a comprehensive reference for researchers and an essential guide for postgraduate students, this work provides valuable insights into the development and utilization of chalcone-based molecules for a wide array of purposes.
- Addresses the lack of in-depth exploration in recent publications, offering a consolidated and holistic perspective on the scaffold's immense potential in various scientific domains
- Highlighting the chalcone scaffold's versatility, showcasing its role as a precursor for diverse organic molecules and its contribution to the synthesis of natural flavonoids
- Underlines the practical significance of chalcones in industries like food and cosmetics, thanks to their UV protection properties
Postgraduate students and researchers working with chalcones and scaffolds
1. Chalcone as a versatile scaffold: An overview
Zainab Ngaini, Saba Farooq
2. Naturally Occurring Chalcones and Their Biological Activities
Nahida Tabassum
3. Chalcones in Drug Discovery and Medicinal Chemistry
Hanhan Dianhar
4. Chalcones: Synthesis strategies and structural modifications
Lei Luo, Hao Shao, Ovas Ahmad Dar
5. Exploring the Anticancer Potential of Chalcones: Mechanistic Insights and Therapeutic Prospects
Shefali Chowdhary, Vipan Kumar
6. Chalcones and their derivatives in food Industry
Shashikant Bhandari, Rajendra Dighe, Ganesh Sonawane, Shweta Sharma, Kajal Pansare Kajal, Ritu Gilhotra
7. Developing hybrid molecules from chalcones: Bridging structures for enhanced properties
Shammy Jindal, Ritesh Jha, Kamya Goyal
8. Chalcones and their derivatives as antioxidants: Insights into their Mechanism and Applications
Poonam Inamdar, Rajendra Dighe, Abhishek Shitole, Sagar Ghanwat , Shambhavi Singh, Shashikant Bhandari, Sharayu Inave, Neha Raut
9. Chalcone incorporating metal complexes and their biomedical applications
Mohmmad Wani, Manzoor Ahmad Malik, Athar Hashmi
10. Chalcones: Structural modification in the synthesis of metal complexes and its applications
Miguel Vázquez, Tania Ivonne Ramírez Candelero, Adriana Galvan, Luis Javier Benitez Puebla, Salvador Mastachi Loza
11. Chalcones and their derivatives as antioxidants: Mechanism and Applications
Nahida Tabassum
12. Chalcone Hybrid Molecules: Combining Structures for Enhanced Properties
Anzar Jahan Anzar, Razia Banoo, Salman Khan
13. Chalcones in Drug Development: Synthesis, Properties and Molecular Docking Insights into Drug Targets and Biological Activity
Begüm Evranos Aksöz
14. Chalcones as Molecular Probes in Chemical Biology and Bioimaging
Santosh Gaonkar, Nidhishree A S, Glanish Jude Martis
15. Photophysical Behaviour of Chalcone Derivatives: Insights and Applications
Harshada Adhyapak, Santosh Gaonkar, Glanish Jude Martis
16. Chalcone Derivatives in Photodynamic Therapy: Illuminating New Treatment Approaches
Vishal Srivastava Cmp Degree College University Of Allahabad, Santosh Kumar
17. The medicinal chemistry of chalcones as potential agents against neglected tropical diseases
Alejandro Camacho-Davila, José Carlos Espinoza-Hicks
18. Chalcones and their derivatives as Anticancer agents: Mechanisms and Applications
Rajendra Dighe, Poonam Inamdar, Yash Shimpi, Kshitij Fattepure, Abhishek Shitole, Pratik Lohakare, Vrushali Pathak, Aditi Saundarkar, Shashikant Bhandari
19. Exploring the antidiabetic potential of chalcones through modulation of /PTP1B and PPARγ
Eduarda Fernandes
20. Chalcone-Based Nanomaterials: Synthesis, Characterization, and Applications
Stalin Thambusamy
21. Chalcones as fluorescence chemo-sensors for detection of metal ions
Stalin Thambusamy
22. Chalcones as versatile probes for metal ion detection
Mangaiyarkarasi Rajendiran, Shanmugavel Chinnathambi
23. Fluorometric and Colorimetric Sensor Properties of Chalcone Derivatives for Detection of Metal ions by UV-spectra/ Emission Spectra
Suhail Ahmed, Salman Khan, Md. Alam
24. Chalcone-Based Nanomaterials: Synthesis, Characterization, and Applications
Shanmugavel Chinnathambi
25. Future Perspective and Emerging Trends in Chalcone Research
Santosh Kumar, Pravin Kumar Singh
Zainab Ngaini, Saba Farooq
2. Naturally Occurring Chalcones and Their Biological Activities
Nahida Tabassum
3. Chalcones in Drug Discovery and Medicinal Chemistry
Hanhan Dianhar
4. Chalcones: Synthesis strategies and structural modifications
Lei Luo, Hao Shao, Ovas Ahmad Dar
5. Exploring the Anticancer Potential of Chalcones: Mechanistic Insights and Therapeutic Prospects
Shefali Chowdhary, Vipan Kumar
6. Chalcones and their derivatives in food Industry
Shashikant Bhandari, Rajendra Dighe, Ganesh Sonawane, Shweta Sharma, Kajal Pansare Kajal, Ritu Gilhotra
7. Developing hybrid molecules from chalcones: Bridging structures for enhanced properties
Shammy Jindal, Ritesh Jha, Kamya Goyal
8. Chalcones and their derivatives as antioxidants: Insights into their Mechanism and Applications
Poonam Inamdar, Rajendra Dighe, Abhishek Shitole, Sagar Ghanwat , Shambhavi Singh, Shashikant Bhandari, Sharayu Inave, Neha Raut
9. Chalcone incorporating metal complexes and their biomedical applications
Mohmmad Wani, Manzoor Ahmad Malik, Athar Hashmi
10. Chalcones: Structural modification in the synthesis of metal complexes and its applications
Miguel Vázquez, Tania Ivonne Ramírez Candelero, Adriana Galvan, Luis Javier Benitez Puebla, Salvador Mastachi Loza
11. Chalcones and their derivatives as antioxidants: Mechanism and Applications
Nahida Tabassum
12. Chalcone Hybrid Molecules: Combining Structures for Enhanced Properties
Anzar Jahan Anzar, Razia Banoo, Salman Khan
13. Chalcones in Drug Development: Synthesis, Properties and Molecular Docking Insights into Drug Targets and Biological Activity
Begüm Evranos Aksöz
14. Chalcones as Molecular Probes in Chemical Biology and Bioimaging
Santosh Gaonkar, Nidhishree A S, Glanish Jude Martis
15. Photophysical Behaviour of Chalcone Derivatives: Insights and Applications
Harshada Adhyapak, Santosh Gaonkar, Glanish Jude Martis
16. Chalcone Derivatives in Photodynamic Therapy: Illuminating New Treatment Approaches
Vishal Srivastava Cmp Degree College University Of Allahabad, Santosh Kumar
17. The medicinal chemistry of chalcones as potential agents against neglected tropical diseases
Alejandro Camacho-Davila, José Carlos Espinoza-Hicks
18. Chalcones and their derivatives as Anticancer agents: Mechanisms and Applications
Rajendra Dighe, Poonam Inamdar, Yash Shimpi, Kshitij Fattepure, Abhishek Shitole, Pratik Lohakare, Vrushali Pathak, Aditi Saundarkar, Shashikant Bhandari
19. Exploring the antidiabetic potential of chalcones through modulation of /PTP1B and PPARγ
Eduarda Fernandes
20. Chalcone-Based Nanomaterials: Synthesis, Characterization, and Applications
Stalin Thambusamy
21. Chalcones as fluorescence chemo-sensors for detection of metal ions
Stalin Thambusamy
22. Chalcones as versatile probes for metal ion detection
Mangaiyarkarasi Rajendiran, Shanmugavel Chinnathambi
23. Fluorometric and Colorimetric Sensor Properties of Chalcone Derivatives for Detection of Metal ions by UV-spectra/ Emission Spectra
Suhail Ahmed, Salman Khan, Md. Alam
24. Chalcone-Based Nanomaterials: Synthesis, Characterization, and Applications
Shanmugavel Chinnathambi
25. Future Perspective and Emerging Trends in Chalcone Research
Santosh Kumar, Pravin Kumar Singh
- Edition: 1
- Published: October 1, 2025
- Language: English
MW
Mohmmad Younus Wani
Mohmmad Younus Wani, PhD, Assistant Professor, Department of Chemistry, College of Science, University of Jeddah, Kingdom of Saudi Arabia. Dr. Wani graduated from Jamia Millia Islamia, New Delhi, India in 2013. Received a senior research fellowship from CSIR-India in 2012 and FCT postdoctoral fellowship from Portugal in 2013. Worked as a postdoctoral fellow with Prof. A. Sobral group from 2013-2016 on the development of fungal cell wall targeted antifungal therapies. In fall 2016, Dr. Wani moved to the University of Texas, USA, Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, UTHealth on the development of non-traditional antimicrobial agents and strategies combating multi-drug resistance. He has many international publications, book chapters, and a book, besides many international and national honours and awards to his credit. Dr. Wani is working hard to advance the medicinal chemistry and drug discovery field with new questions and pertinent issues of 21st century.
Affiliations and expertise
Assistant Professor, Department of Chemistry, College of Science, University of Jeddah, Kingdom of Saudi ArabiaHS
Hao Shao
Hao Shao is an Associate Professor in the school of Civil Engineering & Architecture at Anhui University of Technology. He obtained his Ph.D. from China University of Petroleum (East China) and has visited the section of Safety and Security Science at Delft University of Technology (TUD). He is mainly engaged in industrial system resilience assessment and optimization, complex process system reliability, fire and explosion accident intelligent prevention and control research, so as to prevent petrochemical production accidents and provide effective decision-making for petrochemical production process. His relevant researches provide new ideas and contributions to the development of risk assessment and resilience assessment and optimization methodologies.
Affiliations and expertise
Associate Professor of Medicinal Chemistry in the College of Pharmaceutical Sciences, Southwest University, Chongqing, ChinaAK
Anish Khan
Dr. Anish Khan is currently working as Assistant Professor in Chemistry Department, Centre of Excellence for Advanced Materials Research (CEAMR), Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia. Completed Ph.D. from Aligarh Muslim University, India in 2010. Completed Postdoctoral from School of Chemical Sciences, University Sains Malaysia (USM) in Electroanalytical chemistry in 2010. Working in the field of synthetic biosensor, polymer composites, organic–inorganic electrically conducting nanocomposites. More than 200 research articles, 70 book chapters 30 books published in referred international publisher and more than 20 international conferences/ workshop. More than 30 research projects completed. Editorial board member of more than 11 international journals. Member of American Nano Society.
Affiliations and expertise
Assistant Professor in Chemistry Department, Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia