Limited Offer
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Cellular Immunity in the Peritoneum
- 1st Edition, Volume 371 - July 29, 2022
- Editors: Fernando Aranda Vega, Pedro Berraondo, Lorenzo Galluzzi
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 4 0 0 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 4 0 8 - 8
Adoptive Cell Transfer, Volume 371 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting intere… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteAdoptive Cell Transfer, Volume 371 in the International Review of Cell and Molecular Biology series highlights advances in the field, with this new volume presenting interesting chapters written by an international board of authors who expound on topics such as the Impact of tumor microenvironment on Adoptive Cell Transfer activity, Dendritic Cell Transfer, CAR-T Cell dysfunction and exhaustion, NK Cell-based cancer immunotherapy, Enabling CAR-T cells for solid tumors: rage against the suppressive tumor microenvironment, Improving Adoptive T-Cell therapy with cytokines administration, and What will (and should) be improved in Immunotherapy with CAR?
- Publishes only invited review articles on selected topics
- Authored by established and active cell and molecular biologists and drawn from international sources
- Offers a wide range of perspectives on specific subjects
Academic, government and industrial sectors
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter One: The role of dendritic cells in the immune niche of the peritoneum
- Abstract
- 1: Functions and general features of dendritic cells
- 2: The different subsets of dendritic cells
- 3: Dendritic cells in the immune niche of the peritoneal cavity
- 4: Dendritic cells in the Omentum
- 5: Dendritic cells in the Mesentery and gut-associated lymphoid tissue (GALT)
- 6: Concluding remarks
- References
- Chapter Two: T cells in the peritoneum
- Abstract
- 1: Introduction
- 2: Effector T cells
- 3: T helper cells
- 4: Cytotoxic T lymphocyte (CD8 + CTLs)
- 5: Mucosal-associated invariant T cells (MAIT)
- 6: γδ T cell population
- 7: Suppressor or T regulatory cells (Tregs)
- 8: Constitutive Tregs
- 9: Cancers and peritoneum T cells
- 10: Cell interactions in the peritoneal cavity and omentum
- 11: Concluding remarks
- References
- Chapter Three: Innate immune response to peritoneal bacterial infection
- Abstract
- 1: Peritoneal bacterial infections
- 2: Anatomy of the peritoneal cavity
- 3: Innate immune response-based therapies in peritoneal bacterial infections
- 4: Conclusions
- References
- Chapter Four: The tumor immune microenvironment in peritoneal carcinomatosis
- Abstract
- 1: Introduction to the normal peritoneal microenvironment
- 2: The peritoneum in metastasis
- 3: The tumor immune microenvironment
- 4: The TIME in peritoneal metastases
- 5: Ongoing research
- 6: Conclusion and future perspectives
- References
- Chapter Five: Immune response and locoregional treatments for peritoneal carcinomatosis
- Abstract
- 1: Introduction
- 2: Immunological features of the peritoneum
- 3: Ongoing research
- 4: Conclusion
- References
- Chapter Six: Omentum: Friend or foe in ovarian cancer immunotherapy?
- Abstract
- 1: Introduction
- 2: Milky spots and their immunological role
- 3: Tumor metastasis and ovarian peritoneal carcinomatosis origin
- 4: Concluding remarks
- Acknowledgments
- References
- No. of pages: 144
- Language: English
- Edition: 1
- Volume: 371
- Published: July 29, 2022
- Imprint: Academic Press
- Hardback ISBN: 9780323994002
- eBook ISBN: 9780323994088
FA
Fernando Aranda Vega
Fernando Aranda holds a BSc in Biology (2006) and Biochemistry (2007) from the University of Navarra. Then, he specialized in different strategies of Cancer Immunotherapy with a MSc in Biomedical Research (2008), and a PhD Degree (2012) from the University of Navarra (Pamplona) – Cima University of Navarra. More than 12 years in translational research focus on antitumor immune responses and Cancer Immunotherapy. Author of 64 publications indexed in PubMed in prestigious international journals, with h-index 30 and 4,296 cites (October 2022). He completed the Program of Sara Borrell (ISCIII) -competitive Postdoctoral contract- in the Group of Immune Receptors of the Innate and Adaptive System (IDIBAPS), Barcelona (2016-2018). Co-author of 1 invention patent: Composition based on the fibronectin domain A for the treatment of melanoma - WO/2011/101332. In 2012, Fernando Aranda obtained a Scientific Award, "Profesor Durantez" II Edición, for the best scientific article in Tumor Immunology by Fundación LAIR. Recently, Fernando Aranda awarded a competitive Research Fellow contract “Miguel Servet tipo I” by Instituto de Salud Carlos III, to continue his independent researcher career (IP) in cancer immunotherapy issues. Specifically, he is involved in Translational Immunotherapy of Peritoneal Carcinomatosis. Currently, Fernando Aranda leads a research group in cooperation with Dr. Pedro Berraondo.
Affiliations and expertise
Fernando Aranda Vega, CIMA Universidad de Navarra, Program of Immunology and Immunotherapy, SpainPB
Pedro Berraondo
Pedro Berraondo graduated in Pharmacy at the University of Navarra in 1999. In 2004 he obtained the Ph.D. at the same university. Next, he worked at the Pasteur Institute in Paris (France) under the supervision of Dr. Claude Leclerc, where he developed novel strategies in tumor immunotherapy within the European THERAVAC project. In February 2007, he joined the Immunology and Immunotherapy Program at the Cima Universidad de Navarra, where he leads the Cytokine-based Immunotherapy laboratory. He is co-inventor of ten patents and he is co-author of more than 140 publications, including publications in Nature, Nature Medicine, Nature Reviews Drug Discovery, Immunity, Cancer Discovery, and Cancer Cell. He was certified as a full professor in 2021 by AQU. He is co-director of the degree of expert in immunooncology at the Faculty of Medicine of the University of Navarra, and is in charge of the undergraduate course of macromolecular structure at the Faculty of Sciences of the University of Navarra. He is also the coordinator of the immuno-oncology work module at CIBERONC.
Affiliations and expertise
CIMA Universidad de Navarra, Program of Immunology and Immunotherapy, SpainLG
Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.
Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:
OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Affiliations and expertise
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA