Cellular Aspects of Membrane Permeability

Introduction

Acknowledgments

Part I. The Permeability Characteristics of Living Membranes

Chapter 1. Distribution of Ions and Molecules between Two Phases Separated by a Living Membrane


1. Ionic Composition of Rat Aortic Smooth Muscle Fibers


2. Kinetics of Release of Radioactive Sodium, Sulphate and Sucrose from the Frog Sartorius Muscle


3. Amino Acid Composition of Biological Fluids

Chapter 2. Nature of the Forces Responsible for the Movement of Ions and Molecules Across Living Membranes


1. Inorganic Ions


2. Organic Ions


3. Organic Molecules

Chapter 3. Origin of the Electrical Potential Difference Existing across Most of the Living Membranes


1. Electrokinetic Phenomena


2. Orientation of Fixed Charges


3. Electrochemical Potential


4. Electrogenic Nature of Active Ion Transport

Chapter 4. Significance of the Active Transport of Cations

Chapter 5. Enzymatic Aspects of Membrane Permeability


1. Active Transport in Relation to Cell Metabolism


2. Identification in Crab Nerve of an Enzyme System Hydrolyzing ATP


3. Isolation of a Specific ATPase from other Cells


4. The Effect of Cardiac Glycosides


5. Relationship between ATP Hydrolysis and the Transport of Cations

Chapter 6. Hormones and Permeability Characteristics of Living Membranes


1. Neurohypophyseal Hormones


2. Insulin


3. Parathormone


4. Aldosterone


5. Other Hormones


6. Summary

Chapter 7. Alkaline Earths and Permeability Characteristics of Living Membranes


1. Passive Permeability


2. Active Transport


3. Possible Mechanism of Action

Part II. Cellular Differentiation and Temporo-spatial Distribution of Permeability Characteristics

Chapter 8. Electrical Potential Profiles of Epithelial Tissues


1. Skin and Urinary Bladder of Amphibians


2. Structural Organization of Amphibian Skin in Relation to Function


3. Intestinal Epithelium of the Tortoise


4. Respiratory Epithelium

Chapter 9. Conducting Membranes


1. The Action Potential


2. Nature of the Permeability Change


3. The Permeability Change


4. Energy Requirements


5. Adaptations

Chapter 10. Nervous Control of Permeability Characteristics

Chapter 11. Relationships between Inorganic Ions, Sugars, Amino Acids, Fatty Acids and Bioelectric Potentials

Chapter 12. Osmoregulation and Nitrogen Metabolism


1. Osmoregulatory Function of Amino Acids


2. Some Factors Affecting the Metabolism of Amino Acids


3. Activity of the L-Glutamic Acid Dehydrogenase in Relation to the Regulation of the Pool of Free Amino Acids


4. Urea as Osmotic Effector

Part III. Chemical Nature and Physical Structure of Living Membranes in Relation to Function

Chapter 13. Chemical Nature of Living Membranes

Chapter 14. Physical Structure of Living Membranes


1. From Chemistry to Ultrastructure


2. The Structure of the Cellular Surface


3. Structural Organization as Deduced from Function

Chapter 15. Concluding Remarks

Bibliography

Index

Other Titles in the Division