Cell Death Part A
- 1st Edition, Volume 205 - April 15, 2026
- Latest edition
- Editors: Lorenzo Galluzzi, Lorenzo Galluzzi, Manuel Beltrán Visiedo, Emma Guilbaud, Ruth Soler-Agesta
- Language: English
This comprehensive volume explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical… Read more
This comprehensive volume explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical sciences. The book brings together leading experts to discuss both established and emerging approaches for studying cell death, with a strong emphasis on practical laboratory techniques and their applications in disease research and drug discovery.
- Explains the underlying molecular and biochemical mechanisms driving various cell death processes
- Presents state-of-the-art experimental techniques and assays for detecting and studying cell death in vitro and in vivo
- Discusses the therapeutic potential of targeting cell death pathways, including drug development, resistance mechanisms, and clinical applications
Researchers and Scientists, Graduate and Postgraduate Students, Medical Professionals and Clinicians
1. Methodologies for Monitoring Alkaliptosis in Cancer Cells
Daolin Tang
2. Protein-complementation assay and DISC analysis
PATRICK LEGEMBRE, dhouha Msalbi and Eden Lebrault
3. Detecting phosphorylated MLKL in murine tissues
Riley M. Williams, Siddharta Balachandran and Bikash Thapa
4. Establishment of different cell death models (Apoptosis, Necroptosis, Pyroptosis)
Dai Chao Xu and Yuanxing Yang
5. Implementation of the FENIX assay to determine anti-ferroptotic properties of test compounds
Markus Morrison, Juliana Huether, Melodie Mallais and Derek A. Pratt
6. CRISPR-Cas9 knockout screens to identify drug resistance genes in Acute Myeloid Leukemia
Cai Huan
7. Cell death assays for the detection of acute kidney tubular necrosis
Andreas Linkermann and Francesca Maremonti
8. Methods of cell death imaging by Incucyte and similar platforms
Ivano Amelio
9. Super-resolution microscopy-based assessment of organellar redox-active iron distribution and its relevance for ferroptosis
Patrizia Agostinis, Francesca Rizzollo, Charlotte Cresens, Benjamin Pavie and Pablo Hernandez-Varas
10. Monitoring inflammasome activation by analysing ASC specks and oligomerisation
Sharad Kumar
11. LPS-induced sepsis/ and TNF-induced SIRS (In vivo cell death models)
Dai Chao Xu and Jianling Liu
12. Evaluating protease activation and inactivation of gasdermin cell death effectors
Christopher LaRock and Doris LaRock
13. Measurement of plasma membrane rupture via confocal microscopy
Fiachra Humphries
Daolin Tang
2. Protein-complementation assay and DISC analysis
PATRICK LEGEMBRE, dhouha Msalbi and Eden Lebrault
3. Detecting phosphorylated MLKL in murine tissues
Riley M. Williams, Siddharta Balachandran and Bikash Thapa
4. Establishment of different cell death models (Apoptosis, Necroptosis, Pyroptosis)
Dai Chao Xu and Yuanxing Yang
5. Implementation of the FENIX assay to determine anti-ferroptotic properties of test compounds
Markus Morrison, Juliana Huether, Melodie Mallais and Derek A. Pratt
6. CRISPR-Cas9 knockout screens to identify drug resistance genes in Acute Myeloid Leukemia
Cai Huan
7. Cell death assays for the detection of acute kidney tubular necrosis
Andreas Linkermann and Francesca Maremonti
8. Methods of cell death imaging by Incucyte and similar platforms
Ivano Amelio
9. Super-resolution microscopy-based assessment of organellar redox-active iron distribution and its relevance for ferroptosis
Patrizia Agostinis, Francesca Rizzollo, Charlotte Cresens, Benjamin Pavie and Pablo Hernandez-Varas
10. Monitoring inflammasome activation by analysing ASC specks and oligomerisation
Sharad Kumar
11. LPS-induced sepsis/ and TNF-induced SIRS (In vivo cell death models)
Dai Chao Xu and Jianling Liu
12. Evaluating protease activation and inactivation of gasdermin cell death effectors
Christopher LaRock and Doris LaRock
13. Measurement of plasma membrane rupture via confocal microscopy
Fiachra Humphries
- Edition: 1
- Latest edition
- Volume: 205
- Published: April 15, 2026
- Language: English
LG
Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.
Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:
OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Affiliations and expertise
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USALG
Lorenzo Galluzzi
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza”. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology.
Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals:
OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
Affiliations and expertise
Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA