Cecil Essentials of Medicine
- 11th Edition - September 25, 2026
- Latest edition
- Authors: Fred J. Schiffman, Eleftherios Mylonakis, Kelly A. McGarry, Mark D. Siegel
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 8 7 9 1 - 6
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 8 7 9 2 - 3
Through ten outstanding editions, Cecil Essentials of Medicine has been a favorite of students, residents, and instructors for its concise, easy-to-read writing style and comprehen… Read more
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Through ten outstanding editions, Cecil Essentials of Medicine has been a favorite of students, residents, and instructors for its concise, easy-to-read writing style and comprehensive coverage of this fast-changing field. The fully revised 11th Edition retains a focus on the high-yield, core knowledge of key importance for students on medicine rotation, residents, and practitioners who need quick access to a concise medical reference. Clinically focused and solidly grounded in basic science, it offers strong clinical content ideally suited for today’s more integrated programs.
- Describes key physiology and cellular mechanisms, followed by comprehensive accounts of the diseases of the organ system or field covered in the chapters
- Features new Key Concepts at the beginning of each chapter that highlight the most important takeaways, and includes a new chapter on transgender health
- Uses a full-color design that enhances readability and retention, while numerous imaging videos cover cardiovascular disease, endoscopy, sphincterotomy, and more
- Offers fully revised and updated content with the latest evidence and insights by leading teachers and experts in the field
- Contains superb images and photographs that vividly illustrate the appearance and clinical features of disease
- An eBook version is included with purchase. The eBook allows you to access all of the text and figures, with the ability to search, customize your content, make notes and highlights, and have content read aloud
Medical students
SECTION I Introduction to Medicine
1. Introduction to Medicine
SECTION II Cardiovascular Disease
2. Structure and Function of the Normal Heart and Blood Vessels
3. Evaluation of the Patient With Cardiovascular Disease
4. Diagnostic Tests and Procedures in the Patient With Cardiovascular Disease
5. Heart Failure and Cardiomyopathy
6. Congenital Heart Disease
7. Valvular Heart Disease
8. Coronary Heart Disease
9. Cardiac Arrhythmias
10. Pericardial and Myocardial Disease
11. Other Cardiac Topics
12. Vascular Diseases and Hypertension
SECTION III Pulmonary and Critical Care Medicine
13. Lung in Health and Disease
14. General Approach to Patients With Respiratory Disorders
15. Evaluating Lung Structure and Function
16. Obstructive Lung Diseases
17. Interstitial Lung Diseases
18. Pulmonary Vascular Diseases
19. Disorders of the Pleura, Mediastinum, and Chest Wall
20. Respiratory Failure
21. Transitions in Care From Pediatric to Adult Providers for Individuals With Pulmonary Disease
SECTION IV Preoperative and Postoperative Care
22. Preoperative and Postoperative Care
SECTION V Renal Disease
23. Renal Structure and Function
24. Approach to the Patient With Renal Disease
25. Fluid and Electrolyte Disorders
26. Glomerular Diseases
27. Major Nonglomerular Disorders of the Kidney
28. Vascular Disorders of the Kidney
29. Acute Kidney Injury
30. Chronic Kidney Disease
SECTION VI Gastrointestinal Disease
31. Common Clinical Manifestations of Gastrointestinal Disease: Abdominal Pain
32. Common Clinical Manifestations of Gastrointestinal Disease: Gastrointestinal Hemorrhage
33. Common Clinical Manifestations of Gastrointestinal Disease: Malabsorption
34. Common Clinical Manifestations of Gastrointestinal Disease: Diarrhea
35. Endoscopic and Imaging Procedures
36. Esophageal Disorders
37. Diseases of the Stomach and Duodenum
38. Inflammatory Bowel Disease
39. Diseases of the Pancreas
SECTION VII Diseases of the Liver and Biliary System
40. Laboratory Tests in Liver Diseases
41. Jaundice
42. Acute and Chronic Hepatitis
43. Acute Liver Failure
44. Cirrhosis of the Liver and Its Complications
45. Disorders of the Gallbladder and Biliary Tract
SECTION VIII Hematologic Disease
46. Hematopoiesis and Hematopoietic Failure
47. Clonal Disorders of the Hematopoietic Stem Cell
48. Disorders of Red Blood Cells
49. Clinical Disorders of Granulocytes and Monocytes
50. Disorders of Lymphocytes 51 Normal Hemostasis
52. Disorders of Hemostasis: Bleeding
53. Disorders of Hemostasis: Thrombosis
SECTION IX Oncologic Disease
54. Cancer Biology
55. Cancer Epidemiology
56. Principles of Cancer Therapy
57. Lung Cancer
58. Gastrointestinal Cancers
59. Genitourinary Cancers
60. Breast Cancer
61. Gynecological Cancer
62. Other Solid Tumors (Head and Neck, Sarcomas, Melanoma, Unknown Primary)
63. Complications of Cancer and Cancer Treatment
SECTION X Endocrine Disease and Metabolic Disease
64. Hypothalamic-Pituitary Axis
65. Thyroid Gland
66. Adrenal Gland
67. Male Reproductive Endocrinology
68. Diabetes Mellitus, Hypoglycemia
69. Obesity
70. Malnutrition, Nutritional Assessment, and Nutritional Support in Adult Patients
71. Disorders of Lipid Metabolism
SECTION XI Women’s Health
72. Women’s Health Topics
SECTION XII Men’s Health
73. Men’s Health Topics
SECTION XIII Diseases of Bone and Bone Mineral Metabolism
74. Normal Physiology of Bone and Mineral Homeostasis
75. Disorders of Serum Minerals
76. Metabolic Bone Diseases
77. Osteoporosis
SECTION XIV Musculoskeletal and Connective Tissue Disease
78. Approach to the Patient With Rheumatic Disease
79. Rheumatoid Arthritis
80. Spondyloarthritis
81. Systemic Lupus Erythematosus
82. Systemic Sclerosis
83. Systemic Vasculitis
84. Crystal Arthropathies
85. Osteoarthritis
86. Nonarticular Soft Tissue Disorders
87. Rheumatic Manifestations of Systemic Disorders and Sjögren’s Syndrome
SECTION XV Infectious Disease
88. Host Defenses Against Infection
89. Laboratory Diagnosis of Infectious Diseases
90. Fever and Febrile Syndromes
91. Bacteremia and Sepsis
92. Infections of the Central Nervous System
93. Infections of the Head and Neck
94. Infections of the Lower Respiratory Tract
95. Infections of the Heart and Blood Vessels
96. Acute Bacterial Skin and Skin Structure Infections
97. Intraabdominal Infections
98. Infectious Diarrhea
99. Infections Involving Bone and Joints
100. Urinary Tract Infections
101. Health Care–Associated Infections
102. Sexually Transmitted Infections
103. Human Immunodeficiency Virus Infection
104. Infections in the Immunocompromised Host
105. Infectious Diseases of Travelers: Protozoal and Helminthic Infections
SECTION XVI Neurologic Disease
106. Neurologic Evaluation of the Patient
107. Disorders of Consciousness
108. Disorders of Sleep
109. Cortical Syndromes
110. Dementia and Memory Disturbances
111. Major Disorders of Mood, Thoughts, and Behavior
112. Autonomic Nervous System Disorders
113. Headache, Neck and Back Pain, and Cranial Neuralgias
114. Disorders of Vision and Hearing
115. Dizziness and Vertigo
116. Disorders of the Motor System
117. Congenital, Developmental, and Neurocutaneous Disorders
118. Cerebrovascular Disease
119. Traumatic Brain Injury and Spinal Cord Injury
120. Epilepsy
121. Central Nervous System Tumors
122. Demyelinating and Inflammatory Disorders
123. Neuromuscular Diseases: Disorders of the Motor Neuron and Plexus and Peripheral Nerve Disease
124. Muscle Diseases
125. Neuromuscular Junction Disease
SECTION XVII Geriatrics
126. The Aging Patient SECTION XVIII Palliative Care
127. Palliative Care
SECTION XIX Alcohol and Substance Use
128. Alcohol and Substance Use
1. Introduction to Medicine
SECTION II Cardiovascular Disease
2. Structure and Function of the Normal Heart and Blood Vessels
3. Evaluation of the Patient With Cardiovascular Disease
4. Diagnostic Tests and Procedures in the Patient With Cardiovascular Disease
5. Heart Failure and Cardiomyopathy
6. Congenital Heart Disease
7. Valvular Heart Disease
8. Coronary Heart Disease
9. Cardiac Arrhythmias
10. Pericardial and Myocardial Disease
11. Other Cardiac Topics
12. Vascular Diseases and Hypertension
SECTION III Pulmonary and Critical Care Medicine
13. Lung in Health and Disease
14. General Approach to Patients With Respiratory Disorders
15. Evaluating Lung Structure and Function
16. Obstructive Lung Diseases
17. Interstitial Lung Diseases
18. Pulmonary Vascular Diseases
19. Disorders of the Pleura, Mediastinum, and Chest Wall
20. Respiratory Failure
21. Transitions in Care From Pediatric to Adult Providers for Individuals With Pulmonary Disease
SECTION IV Preoperative and Postoperative Care
22. Preoperative and Postoperative Care
SECTION V Renal Disease
23. Renal Structure and Function
24. Approach to the Patient With Renal Disease
25. Fluid and Electrolyte Disorders
26. Glomerular Diseases
27. Major Nonglomerular Disorders of the Kidney
28. Vascular Disorders of the Kidney
29. Acute Kidney Injury
30. Chronic Kidney Disease
SECTION VI Gastrointestinal Disease
31. Common Clinical Manifestations of Gastrointestinal Disease: Abdominal Pain
32. Common Clinical Manifestations of Gastrointestinal Disease: Gastrointestinal Hemorrhage
33. Common Clinical Manifestations of Gastrointestinal Disease: Malabsorption
34. Common Clinical Manifestations of Gastrointestinal Disease: Diarrhea
35. Endoscopic and Imaging Procedures
36. Esophageal Disorders
37. Diseases of the Stomach and Duodenum
38. Inflammatory Bowel Disease
39. Diseases of the Pancreas
SECTION VII Diseases of the Liver and Biliary System
40. Laboratory Tests in Liver Diseases
41. Jaundice
42. Acute and Chronic Hepatitis
43. Acute Liver Failure
44. Cirrhosis of the Liver and Its Complications
45. Disorders of the Gallbladder and Biliary Tract
SECTION VIII Hematologic Disease
46. Hematopoiesis and Hematopoietic Failure
47. Clonal Disorders of the Hematopoietic Stem Cell
48. Disorders of Red Blood Cells
49. Clinical Disorders of Granulocytes and Monocytes
50. Disorders of Lymphocytes 51 Normal Hemostasis
52. Disorders of Hemostasis: Bleeding
53. Disorders of Hemostasis: Thrombosis
SECTION IX Oncologic Disease
54. Cancer Biology
55. Cancer Epidemiology
56. Principles of Cancer Therapy
57. Lung Cancer
58. Gastrointestinal Cancers
59. Genitourinary Cancers
60. Breast Cancer
61. Gynecological Cancer
62. Other Solid Tumors (Head and Neck, Sarcomas, Melanoma, Unknown Primary)
63. Complications of Cancer and Cancer Treatment
SECTION X Endocrine Disease and Metabolic Disease
64. Hypothalamic-Pituitary Axis
65. Thyroid Gland
66. Adrenal Gland
67. Male Reproductive Endocrinology
68. Diabetes Mellitus, Hypoglycemia
69. Obesity
70. Malnutrition, Nutritional Assessment, and Nutritional Support in Adult Patients
71. Disorders of Lipid Metabolism
SECTION XI Women’s Health
72. Women’s Health Topics
SECTION XII Men’s Health
73. Men’s Health Topics
SECTION XIII Diseases of Bone and Bone Mineral Metabolism
74. Normal Physiology of Bone and Mineral Homeostasis
75. Disorders of Serum Minerals
76. Metabolic Bone Diseases
77. Osteoporosis
SECTION XIV Musculoskeletal and Connective Tissue Disease
78. Approach to the Patient With Rheumatic Disease
79. Rheumatoid Arthritis
80. Spondyloarthritis
81. Systemic Lupus Erythematosus
82. Systemic Sclerosis
83. Systemic Vasculitis
84. Crystal Arthropathies
85. Osteoarthritis
86. Nonarticular Soft Tissue Disorders
87. Rheumatic Manifestations of Systemic Disorders and Sjögren’s Syndrome
SECTION XV Infectious Disease
88. Host Defenses Against Infection
89. Laboratory Diagnosis of Infectious Diseases
90. Fever and Febrile Syndromes
91. Bacteremia and Sepsis
92. Infections of the Central Nervous System
93. Infections of the Head and Neck
94. Infections of the Lower Respiratory Tract
95. Infections of the Heart and Blood Vessels
96. Acute Bacterial Skin and Skin Structure Infections
97. Intraabdominal Infections
98. Infectious Diarrhea
99. Infections Involving Bone and Joints
100. Urinary Tract Infections
101. Health Care–Associated Infections
102. Sexually Transmitted Infections
103. Human Immunodeficiency Virus Infection
104. Infections in the Immunocompromised Host
105. Infectious Diseases of Travelers: Protozoal and Helminthic Infections
SECTION XVI Neurologic Disease
106. Neurologic Evaluation of the Patient
107. Disorders of Consciousness
108. Disorders of Sleep
109. Cortical Syndromes
110. Dementia and Memory Disturbances
111. Major Disorders of Mood, Thoughts, and Behavior
112. Autonomic Nervous System Disorders
113. Headache, Neck and Back Pain, and Cranial Neuralgias
114. Disorders of Vision and Hearing
115. Dizziness and Vertigo
116. Disorders of the Motor System
117. Congenital, Developmental, and Neurocutaneous Disorders
118. Cerebrovascular Disease
119. Traumatic Brain Injury and Spinal Cord Injury
120. Epilepsy
121. Central Nervous System Tumors
122. Demyelinating and Inflammatory Disorders
123. Neuromuscular Diseases: Disorders of the Motor Neuron and Plexus and Peripheral Nerve Disease
124. Muscle Diseases
125. Neuromuscular Junction Disease
SECTION XVII Geriatrics
126. The Aging Patient SECTION XVIII Palliative Care
127. Palliative Care
SECTION XIX Alcohol and Substance Use
128. Alcohol and Substance Use
- Edition: 11
- Latest edition
- Published: September 25, 2026
- Language: English
FS
Fred J. Schiffman
Affiliations and expertise
Sigal Family Professor of Humanistic Medicine, Vice Chairman of Medicine, Warren Alpert Medical School of Brown University, Medical Director of the Lifespan Cancer Institute, Associate Program Director, Internal Medicine Residency Program, Associate Physician-in-Chief, The Miriam Hospital, Providence, RI, USAEM
Eleftherios Mylonakis
Affiliations and expertise
Chair, Department of Medicine, Houston Methodist Hospital, Charles and Anne Duncan Presidential Distinguished Chair, Professor of Medicine, Weill Cornell Medical College & Houston Methodist, Academic Institute, Houston, TX, USAKM
Kelly A. McGarry
Affiliations and expertise
Professor of Medicine, Alpert Medical School at Brown University, Rhode Island Hospital, Providence, RI, USAMS
Mark D. Siegel
Affiliations and expertise
Program Director; Yale Traditional Internal Medicine Residency; Professor of Internal Medicine (PCCSM); Yale School of Medicine, New Haven, CT, USA