Care for the Term Newborn, An Issue of Clinics in Perinatology

1st Edition, Volume 48-3 - August 6, 2021
Editors: Anup Katheria, Lisa Stellwagen
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 6 8 8 - 7
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 6 8 9 - 4

In this issue of Clinics in Perinatology, Guest Editors Anup Katheria and Lisa Stellwagen bring their considerable expertise to the topic of Care for the Term Newborn. Top… Read more

Care for the Term Newborn, An Issue of Clinics in Perinatology

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In this issue of Clinics in Perinatology, Guest Editors Anup Katheria and Lisa Stellwagen bring their considerable expertise to the topic of Care for the Term Newborn. Top experts in the field cover key topics such as delivery room triage and transitions of care; early onset sepsis; congenital infections; postnatal screening & testing; and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
CME Accreditation Page
Forthcoming Issues
Foreword
Preface
The Term Newborn: Delivery Room Triage and Transitions of Care
Key points
Introduction
Postresuscitation care
Respiratory diseases
Neonatal hypoglycemia
Cardiovascular diseases
Infectious diseases
Hematologic diseases
Neurologic diseases
Special circumstances
Summary
Clinics care points
Cord Management of the Term Newborn
Key points
Introduction
Physiology of placental transfusion
Obstetric considerations
Cord milking
Major benefits of delayed cord clamping for term infants
Are there risks associated with placental transfusion?
Intact cord resuscitation
Practice
Current and future research on placental transfusion
Summary
Clinics care points
The Term Newborn: Early-Onset Sepsis
Key points
Introduction
Epidemiology and microbiology of early-onset sepsis among term infants
Risk factors and clinical presentation of early-onset sepsis
Risk assessment
Laboratory studies
Empirical and definitive treatment
Summary
Clinics care points
The Term Newborn: Congenital Infections
Key points
Introduction
Congenital cytomegalovirus infection
Perinatal human immunodeficiency virus exposure and infection
Breastfeeding and feeding practices
Prophylaxis against Pneumocystis jiroveci
Follow-up of infants exposed to or infected with human immunodeficiency virus
Helpful resources
Syphilis
Toxoplasmosis
Diagnosis and treatment
Congenital Zika virus
Chagas disease
Summary
Clinics care points
Best practices
What are the current best practices for congenital infections related to HIV,CMV, toxoplasmosis, Zika, and Chagas?
Human Milk for the Term Newborn
Key points
Introduction
Epidemiology of human milk for infants
Benefits of mother’s own milk feedings
Risks of mother’s own milk feedings
Considerations for expressed breast milk
Supplementation
Human milk for the term newborn in the neonatal intensive care unit
Evidence-based support for lactation for mothers of term newborns
Public policies to improve human milk for the term newborn
Summary
Hyperbilirubinemia in the Term Infant: Re-evaluating What We Think We Know
Key points
Introduction
The wide clinical spectrum of bilirubin neurotoxicity
Is kernicterus spectrum disorder still a problem?
Coronavirus and other pandemics
Hereditary background to neonatal hyperbilirubinemia
Effect of race, ethnicity, and geography on neonatal hyperbilirubinemia
Should bilirubin nomograms be universal?
Modern technologies in the assessment of neonatal hyperbilirubinemia
Treatment of hyperbilirubinemia
Is acute bilirubin encephalopathy invariably associated with severe, chronic neurologic dysfunction?
Clinics care points
The Term Newborn: Postnatal Screening and Testing
Key points
Introduction
Prenatal genetic screening
Newborn assessment
Standard newborn screening
Summary
Perinatal Cardiovascular Physiology and Recognition of Critical Congenital Heart Defects
Key points
Introduction
Fetal cardiovascular system
Transition from fetal to neonatal circulation in term infants
Resuscitation and delayed cord clamping in infants with congenital heart defects
Clinical presentation of infants with congenital heart defects
Cyanotic CHDs
Acyanotic congenital heart defects
Clinical presentation of infant with critical CHD
An approach to understand cardiovascular physiology in infants presenting as neonatal emergency
A simplified approach to evaluation and initial management of infants with suspected congenital heart disease
Use of prostaglandin E1 infants with critical CHDs
Establishing a definitive diagnosis of CHD
Summary
Clinics care points
Pathophysiology and Management of Persistent Pulmonary Hypertension of the Newborn
Key points
Introduction
Classification of persistent pulmonary hypertension of the newborn
Pathophysiology of persistent pulmonary hypertension of the newborn
Mechanism of pulmonary vasculature remodeling and basis of therapeutic intervention in persistent pulmonary hypertension of the newborn
Diagnosis of persistent pulmonary hypertension of the newborn
General supportive management
Oxygen saturation targets in managing infants with persistent pulmonary hypertension of the newborn
Mechanical ventilation
Surfactant therapy
Pulmonary vasodilator therapy
Role of prostaglandin E1 in management of persistent pulmonary hypertension of the newborn
Supporting systemic blood pressure
Role of extracorporeal membrane oxygenation
Summary
Clinics care points
Author contributions
Sudden Unexpected Infant Death: Keeping the Newborn Safe in Hospital and at Home
Key points
Introduction
Achieving both safe sleep and breastfeeding
Special circumstances
Summary
Clinics care points
The Term Newborn: Prenatal Substance Exposure
Key points
Introduction
Screening for substance use disorders during pregnancy
Medical comorbidities
Specific effects of commonly used substances
Teaming up for postdischarge care
Clinics care points
The Term Newborn: Alternative Birth Practices, Refusal, and Therapeutic Hesitancy
Key points
Introduction
Hesitancies and refusals in the well newborn unit
Refusals and alternatives in labor and delivery
Strategies to address hesitancy and refusal
Summary
Clinics care points
The Term Newborn: Hypoglycemia
Key points
Introduction
Fetal and neonatal glucose homeostasis
Definitions of hypoglycemia
Screening and management guidelines
Measurement of glucose
Prevention and treatment of neonatal hypoglycemia
Special populations of infants with neonatal hypoglycemia
Risk of adverse neurodevelopmental outcomes
Learning from medical legal claims
Summary
Clinics care points
The Term Newborn: Evaluation for Hypoxic-Ischemic Encephalopathy
Key points
Introduction
Summary
Clinics care points

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Care for the Term Newborn, An Issue of Clinics in Perinatology

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Anup Katheria

Lisa Stellwagen