Cardio-oncology, An Issue of Cardiology Clinics

1st Edition, Volume 43-1 - November 21, 2024
Editors: Eric H. Yang, Ashley F. Stein-Merlob
Language: English
Hardback ISBN:
9 7 8 - 0 - 4 4 3 - 2 4 6 8 4 - 5
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 2 4 6 8 5 - 2

In this issue of Cardiology Clinics, guest editors Drs. Eric H. Yang and Ashley F. Stein-Merlob bring their considerable expertise to the topic of Cardio-oncology. Top experts d… Read more

Cardio-oncology, An Issue of Cardiology Clinics

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In this issue of Cardiology Clinics, guest editors Drs. Eric H. Yang and Ashley F. Stein-Merlob bring their considerable expertise to the topic of Cardio-oncology. Top experts discuss key topics such as anthracycline-induced cardiotoxicity; cardiac complications of immunotherapy: immune checkpoint inhibitors and CAR T cell therapy; advances in diagnosis and treatment of amyloid cardiomyopathy; guidelines in cardio-oncology; and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Cardiovascular Risk Assessment and Prevention in Cardio-Oncology: Beyond Traditional Risk Factors
Key points
Introduction
Emerging risk factors
Access to care
Neighborhood
Financial toxicity
Health insurance coverage
Environmental factors and air quality
Microbiome
Novel methods of risk factor detection and prevention
Multi-omics approach
Advanced imaging studies and radiomics
Machine learning and large language models
Summary and concluding remarks
Clinics care points
Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Health
Key points
Introduction
Clonal hematopoiesis of indeterminate potential
Risk factors for clonal hematopoiesis of indeterminate potential
Clinical associations
Mechanisms of cardiovascular disease
Therapeutic strategies
Summary
Clinics care points
Unique Challenges of Adult Congenital Heart Disease in CardioOncology
Key points
Introduction
Syndromes associated with congenital heart disease and increased risk of cancer
Patients with complex single ventricle physiology and risk of hepatocellular carcinoma
Risk of thymectomy and cancer
Radiation exposure and cancer
Inadequate cancer screening in adult congenital heart disease patients
Cancer treatment in adult congenital heart disease patients
Summary
Clinics care points
Classes of Antineoplastic Agents Associated with Increased Risk of Cancer Therapy-associated Hypertension and Management Strategies
Key points
Introduction
Why does cancer therapy-associated hypertension matter?
Classes of cancer therapies associated with hypertension
Diagnosis and management of cancer therapy-related hypertension
Summary
Clinics care points
Arrhythmia Challenges in Cardio-Oncology: High-Risk Therapies, Management, and Anticoagulation
Key points
Introduction
Atrial fibrillation
Ventricular arrhythmias
Bradyarrhythmia and blocks
Summary
Clinics care points
Ischemic Heart Disease in the Cancer Population: Trends, Outcomes, Epidemiology, and Challenges in Diagnosis and Treatment
Key points
Introduction
Discussion
Summary
Clinics care points
Cardiovascular Health in Breast Cancer: Survivorship Care
Key points
Introduction
The team
Education of patients
New breast cancer therapies
Radiation therapy
Promoting healthy behaviors
Future direction
Clinics care points
Cardiovascular Risk in Prostate Cancer
Key points
Introduction
Epidemiology of cardiovascular disease in patients with prostate cancer
Mechanisms underlying cardiovascular disease in prostate cancer
Addressing cardiovascular risk in patients with prostate cancer
Management of severe cardiovascular disease in patients with metastatic prostate cancer
Summary
Clinics care points
Evolving Strategies in Cardiac Amyloidosis: From Mechanistic Discoveries to Diagnostic and Therapeutic Advances
Key points
Introduction
Epidemiology of cardiac amyloidosis
Pathophysiology of cardiac amyloidosis
Diagnosis of cardiac amyloidosis
Treatment of ATTR-cardiomyopathy
Treatment of AL-cardiomyopathy
Racial, gender, and socioeconomic disparities in cardiac amyloidosis
Summary
Clinics care points
Cardiotoxicity of Anthracyclines
Key points
Introduction
Clinical manifestations
Pathogenesis
Incidence
Risk assessment
Pretreatment imaging
Preventive strategies
Surveillance and diagnosis
Management of anthracycline cardiotoxicity
Long-term surveillance in survivors of adult cancers
Adult survivors of childhood cancer
Future directions
Clinics care points
Cardiac Complications of Radiation Therapy
Key points
Introduction
Summary of radiation principles
Radiation-induced cardiovascular disease: clinical trials and cohort studies
Pathophysiology of radiation-induced cardiac toxicity
Risk factors of radiation-induced cardiotoxicity
Screening for radiation-induced cardiotoxicity
Management of radiation-induced cardiotoxicities
Novel therapeutic applications of radiation therapy in cardiac conditions
Summary
Clinics care points
Cardiac Complications of Immune Checkpoint Inhibitors and Chimeric Antigen Receptor T Cell Therapy
Key points
Introduction
Mechanisms of cardiotoxicity
Epidemiology, manifestations, and clinical features
Diagnostic studies
Management
Prognosis and surveillance
Impact of cardiometabolic, socio-economic and environmental factors on immunotherapy induced cardiotoxicity
Future directions in the management of cardiac immune-related adverse events
Summary
Clinics care points
Cardio-oncology Drug Interactions: A Primer for Clinicians on Select Cardiotoxic Oncologic Therapies
Key points
Introduction
Discussion
Summary
Clinics care points
Cardio-Oncology Program Building: A Practical Guide
Key points
Core people and teams: the building blocks of a cardio-oncology program
Key services, workflow, and integration within health care system
Strategies for building a successful cardio-oncology program
Clinics care points

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Cardio-oncology, An Issue of Cardiology Clinics

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Eric H. Yang

Ashley F. Stein-Merlob