Cardiac Conduction System Disorders, An Issue of Cardiac Electrophysiology Clinics

1st Edition, Volume 13-4 - October 28, 2021
Editors: Eric N. Prystowsky, Benzy Padanilam
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 7 3 6 - 5
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 9 7 3 7 - 2

In this issue of Cardiac Electrophysiology Clinics, Guest Editors Eric N. Prystowsky and Benzy Padanilam bring their considerable expertise to the topic of Cardiac Conduction S… Read more

Cardiac Conduction System Disorders, An Issue of Cardiac Electrophysiology Clinics

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In this issue of Cardiac Electrophysiology Clinics, Guest Editors Eric N. Prystowsky and Benzy Padanilam bring their considerable expertise to the topic of Cardiac Conduction System Disorders. Top experts in the field cover key topics such as sinus node abnormalities, electrocardiography of AV block, AV conduction, pacemaker-induced cardiomyopathy, and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Anatomy and Pathology of the Cardiac Conduction System
Key points
Introduction
The sinus node
Internodal and interatrial conduction
Atrioventricular node and atrioventricular connections
The His bundle and bundle branches
Fascicles and the distal Purkinje system
Retroaortic node and blind-end tract
Intraventricular conduction
Summary
Clinics care points
Disclosure
Atrioventricular Conduction: Physiology and Autonomic Influences
Key points
Introduction
Atrioventricular node
His-Purkinje system
Atrioventricular node conduction
Supraventricular tachycardia and autonomic nervous system
Electrocardiography of Atrioventricular Block
Key points
Introduction
Atrioventricular delayed conduction
Dual atrioventricular node physiology
Second degree type 1 atrioventricular block (Wenckebach; Mobitz 1)
Second degree type 2 atrioventricular block (Mobitz II)
Two to one atrioventricular block
Paroxysmal atrioventricular block
Complete heart block
Clinics care points
Physiologic Variants of Cardiac Conduction (Aberration, Gap, Supernormal Conduction)
Key points
Introduction
Differentiation of ventricular tachycardia from supraventricular tachycardia with aberrancy
Long-short aberrancy
Functional 2:1 atrioventricular block
Acceleration-dependent and deceleration-dependent aberrancy
Mechanistic implications of aberration: bundle branch block during supraventricular tachycardia
Mechanistic implications of aberration: concealed His extrasystoles
Gap phenomenon
Equal bundle branch delay
Supernormal conduction
Summary
Disclosure
Clinics care points
Genetic Abnormalities of the Sinoatrial Node and Atrioventricular Conduction
Key points
Introduction
2. Ion channels
3. Structural proteins
4. Nuclear proteins
5. Metabolism proteins
Summary
Clinics care points
Disclosure
Sinus Node Dysfunction
Key points
Introduction
Summary
Clinics care points
Disclosure statement
Epidemiology and Outcomes Associated with PR Prolongation
Key points
Introduction/history/definitions/background
Discussion
Summary
Clinics care points
Disclosure statement
Left Bundle Branch Block: Characterization, Definitions, and Recent Insights into Conduction System Physiology
Key points
Introduction/background
Epidemiology
Anatomy of the left bundle
Definitions and criteria for true left bundle branch block
Electromechanical effects of left bundle branch block
Clinical significance of left bundle branch block
Correcting left bundle branch block with conduction system pacing
Summary
Clinics care points
Bilateral Bundle Branch Block
Key points
Introduction
Definition and prevalence
Pathophysiology
Clinical implications and future perspectives
Clinics care points
Disclosures
Congenital Heart Block
Key points
Mechanisms of congenital heart block
Natural history
Evaluation and treatment
Summary
Clinics care points
Reversible Causes of Atrioventricular Block
Key points
Introduction
Epidemiology
Management
Ischemic disease
Drugs
Electrolyte alterations
Increased vagal tone
Infectious causes
Endocarditis
Hypothermia
Trauma
Final conclusions: waiting is key
Clinics care points
Iatrogenic Atrioventricular Block
Key points
Introduction
Anatomy
Cardiac surgery
Transcatheter aortic valve replacement
Catheter ablation of arrhythmias
Other percutaneous procedures
Summary
Clinics care points
Systemic Diseases and Heart Block
Key points
Introduction
Classification
Summary
Clinics care points
Pacing-Induced Cardiomyopathy
Key points
Introduction
Pathophysiology of PICM
PICM frequency and risk factors
Upfront physiologic pacing
Treatment of PICM
Authors’ approach
Future outlook
Summary
Disclosure
Pacing of Specialized Conduction System
Key points
Introduction
Magnitude and pathophysiology of pacing-induced cardiomyopathy
Inception of conduction system pacing
Mechanisms of Correction of Bundle Branch Blocks with Conduction System Pacing
Conduction system pacing implantation techniques
Confirmation of conduction system capture and definitions
Conduction system pacing for atrioventricular block
Conduction System Pacing for refractory atrial fibrillation before atrioventricular junction ablation
Conduction system pacing for cardiac resynchronization therapy
Conduction system pacing for pacing-induced cardiomyopathy
Conduction system pacing for painful left bundle branch syndrome
Chronic lead performance and complications
Anatomy and histology of the conduction system
Future directions
Summary
Funding