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Elsevier

Brody's Human Pharmacology

With STUDENT CONSULT Online Access

  • 5th Edition - March 5, 2009
  • Latest edition
  • Authors: Lynn Crespo, George Dunaway, Carl Faingold, Stephanie Watts
  • Editor: Lynn Wecker
  • Language: English

With contributions from leading faculty, this new edition provides a clear and concise overview of the most important aspects of pharmacology necessary for a basic understanding of… Read more

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Description

With contributions from leading faculty, this new edition provides a clear and concise overview of the most important aspects of pharmacology necessary for a basic understanding of the subject. It reviews the concepts, clinical applications and side effects of pharmacology, emphasising practical applications of the material, whenever possible. A consistent style of writing, and more focused content, help you to better master the essentials.

Key features

  • Includes online access to Student Consult where you’ll find USMLE-style questions, animations showing the actions of various important toxins, and much more.
  • Focuses on the essential aspects of pharmacology for a solid foundation of knowledge in the subject.
  • Includes more than 480 full-color illustrations that explain key pharmacologic processes.
  • Provides between 4 and 6 USMLE-style self-assessment questions at the end of each chapter—with answers and full explanations in the appendix—that help you prepare for exams and master the material.
  • Uses a templated format that promotes more effective and efficient learning.
  • Presents color-coded boxes in each chapter that emphasize key points.
  • Features a clinical emphasis throughout on both the basic science of pharmacology and its clinical relevance.
  • Includes new Gold Standard content on Student Consult with 200 Professional Drug Monographs for additional information on generic and brand names, mechanism of action, pharmacokinetics, indications and dosage, drug interactions, patient education and much more!

Readership

1st and 2nd year medical students

Table of contents

Part I: General Principles, Lynn Wecker


1 Pharmacodynamics: Receptors and Concentration-Response Relationships


2 Pharmacokinetics: Absorption, Distribution, Metabolism and Elimination


3 Clinical Pharmacokinetics and Issues in Therapeutics


4 Drug Development, Regulation and Prescription Writing


5 Gene Therapy and Emerging Molecular Therapies


6 Antibodies and Biological Products


7 Herbals and Natural Products


8 Principles of Toxicology

Part II: Drugs Affecting the Peripheral Nervous System, Skeletal and Smooth Muscle, Carl Faingold


9 Introduction to the Autonomic Nervous System


10 Drugs Affecting the Parasympathetic Nervous System and Autonomic Ganglia


11 Drugs Affecting the Sympathetic Nervous System


12 Skeletal Muscle Relaxants


13 Local Anesthetics


14 Histamine and Antihistamines


15 Eicosanoids


16 Drugs to Treat Asthma and Chronic Obstructive Pulmonary Disease


17 Drugs Affecting Uterine Motility


18 Drugs Affecting the Gastrointestinal System

Part III: Drugs Affecting the Cardiovascular, Renal and Circulatory Systems, Stephanie Watts


19 Introduction to the Regulation of Cardiovascular Function


20 Antihypertensive Drugs


21 Diuretic Drugs


22 Antiarrhythmic Drugs


23 Drugs to Treat Heart Failure


24 Vasodilators and Nitric Oxide Synthase


25 Lipid-Lowering Drugs and Atherosclerosis


26 Antithrombotic Drugs

Part IV: Drugs Affecting the Central Nervous System, Lynn Wecker


27 Introduction to the Central Nervous System


28 Treatment of Parkinson’s and Alzheimer's Diseases


29 Treatment of Psychotic Disorders


30 Treatment of Affective Disorders


31 Treatment of Anxiety and Insomnia


32 Ethanol, Other Alcohols and Drugs for Alcohol Dependence


33 Treatment of Obesity and Eating Disorders


34 Treatment of Seizure Disorders


35 General Anesthetics


36 Drugs to Control Pain


37 Drugs and Substance Abuse, Addiction and Treatment

Part V: Drugs Affecting Endocrine Systems, George Dunaway


38 Introduction to Endocrine Pharmacology and Hormones of the Hypothalamus and Pituitary Gland


39 Adrenocorticosteroids


40 Estrogens and Progestins


41 Androgens and Antiandrogens


42 Thyroid and Antithyroid Drugs


43 Insulin and Drugs Used in the Therapy of Diabetes Mellitus


44 Calcium-Regulating Hormones and Other Agents Affecting Bone

Part VI: Chemotherapy of Invading Organisms, Lynn Crespo


45 Principles of Antimicrobial Use


46 Bacterial Cell Wall Synthesis Inhibitors


47 Inhibitors of Bacterial Ribosomal Actions


48 Bacterial Folate Antagonists, Fluoroquinolones, and Other Antibacterial Agents


49 Antimycobacterial Agents


50 Antifungal Agents


51 Antiviral Agents


52 Drugs to Treat Parasitic Infections

Part VII: Chemotherapy of Neoplastic Diseases, Lynn Crespo


53 Principles of Antineoplastic Drug Use


54 Mechanisms of Action of Antineoplastic Drugs


55 Adjuvant Antineoplastic Drugs

Review quotes

A recent review of: Brody’s Human Pharmacology: Molecular to Clinical, 5th Edition

[Excerpt from a review by Thomas L. Pazdernik, PhD (University of Kansas Medical Center), from Doody’s Reviews]

This is by far the best edition of this book since section editors have made certain that each chapter is current and follows the same format of therapeutic overview, mechanisms of action, pharmacokinetics, relation of mechanisms of action to clinical response, pharmacovigilance (side effects, clinical problems, and toxicity), and new horizons. The focus is on prototypic drugs with ample use of tables and boxes to provide valuable summaries of how important clinical drugs differ from the prototypic drugs described in detail.

The multicolored figures are both attractive and informative. Each chapter ends with a short, relevant, up-to-date further reading list and a few self-assessment questions. The questions highlight key concepts and drugs covered in the chapter, but are not of the style or complexity of questions currently used on USMLE examinations. Excellent descriptive answers to the self-assessment questions are provided in the appendix. Buyers are also provided with a PIN number for a Student Consult web site which includes complete contents of the book online plus multiple choice questions with feedback as well as other learning enrichments.

This edition is a markedly improved book that rivals Basic and Clinical Pharmacology, 10th edition, by Katzung (McGraw-Hill, 2007), as a leading pharmacology textbook for teaching pharmacology to health professionals. I highly recommend this fifth edition for adoption.

Weighted Numerical Score: 94 - 4 Stars!

Product details

  • Edition: 5
  • Latest edition
  • Published: March 5, 2009
  • Language: English

About the editor

LW

Lynn Wecker

Professor Lynn Wecker has recently retired from teaching at USF College of Medicine Tampa Florida, and has agreed to stay on for a final edition to help Susan learn the ropes.
Affiliations and expertise
Distinguished University Professor, Departments of Psychiatry and Behavioral Medicine and Molecular Pharmacology and Physiology, Director, Laboratory of Neuropsychopharmacology, USF College of Medicine, Tampa, Florida, USA

About the authors

LC

Lynn Crespo

Affiliations and expertise
Professor, Department of Medical Education Assistant Dean of Undergraduate Medical Education, University of Central Florida College of Medicine, Orlando, FL

GD

George Dunaway

Affiliations and expertise
Professor, Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL

CF

Carl Faingold

Carl L. Faingold is an American neuroscientist who is a Distinguished Professor in the Department of Pharmacology of Southern Illinois University School of Medicine in Springfield, Illinois; he is a founding faculty member of both the department and the School of Medicine.
Affiliations and expertise
Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, USA

SW

Stephanie Watts

Affiliations and expertise
Professor, Department of Pharmacology and Toxicology, Michigan State University, East Lansing, MI