Brain Signal Transduction and Memory

Foreword

Preface

I. Overviews

Phosphoinositides and Neural Signaling

The Heterogeneity of Protein Kinase C and Its Implications for Neuronal Cell Regulation

Molecular Mechanisms for Long-Term Memory in Aplysia

II. Homeostasis of Calcium Ions

Mechanisms Underlying the Generation and Control of [Ca2-]i Transients in Neurons and Neurosecretory Cells

Heterogeneous Distribution and Temporal Changes of Cytoplasmic Free Calcium in Gastric Parietal Cells and Platelets

The Role of Ca2+/Calmodulin-Dependent Protein Kinase II in Neuronal Functions

III. Involvement of Protein Kinase C

Cytochemical Evidence of Protein Kinase C in Neuronal Tissues

The Protein Kinase C Substrate Protein B-50 in Neural Signal Transduction and Plasticity

Modulation of Two K + Currents by Inositol Trisphosphate and Protein Kinase C

The Role of Protein Kinase C and Phosphoinositide Metabolites in Neurons That Control Prolonged Reproductive Behaviors in Aplysia

IV. Long-Term Potentiation in the Hippocampus

Quantal Release in the Hippocampus

Mechanisms Involved in the Initiation and Expression of Long-term Potentiation

Cholinergic and Noradrenergic Modulation of Long-Term Potentiation in Hippocampal CA3 Neurons

Presynaptic Mechanisms Underlying the Maintenance of Long-term Potentiation in the Hippocampus

V. Synaptic Plasticity and Memory

Molecular Mechanisms of Long-Term Depression in the Cerebellum

Molecular Basis for the Hebb Synapse

The Physical Reality of Memory

Molecular Mechanisms Underlying Synaptic Plasticity in the Developing Visual Cortex

VI. Organization of Neural Tissues by Plasticity

Terminal Sprouting and Functional Plasticity at Neuromuscular Junctions

Roles of Nerve Growth Factor in the Central Nervous System

Cellular Mechanisms for Reorganization of Synaptic Inputs after Early Brain Damage

Index