Brain Machine Interfaces
Implications for Science, Clinical Practice and Society
- 1st Edition, Volume 194 - October 12, 2011
- Latest edition
- Editors: Jens Schouenborg, Martin Garwicz, Nils Danielsen
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 4 - 5 6 2 2 8 - 9
- Hardback ISBN:9 7 8 - 0 - 4 4 4 - 5 3 8 1 5 - 4
- eBook ISBN:9 7 8 - 0 - 4 4 4 - 5 3 8 1 6 - 1
This volume follows on from the symposium "Brain Machine Interfaces - Implications for science, clinical practice and society", held on August 26th-29th 2010 in Ystad, Sweden, an… Read more
This volume follows on from the symposium "Brain Machine Interfaces - Implications for science, clinical practice and society", held on August 26th-29th 2010 in Ystad, Sweden, and features contributions from pioneers and leading scientists in the field of BMI and motor systems physiology, including spinal cord, basal ganglia and motor cortex. The wide range of topics covered include implants for mind control of prostheses and in robotics, clinical and experimental research on Deep Brain Stimulation (DBS) for the treatment of Parkinson’s disease, depression and Alzheimer’s disease, cochlear implants, retinal implants, novel flexible micro- and nano-electrode implants, safety aspects including acute and chronic tissue reactions to implants and on ethical issues in DBS. Program and abstracts from the individual contributors can be found on http://www.med.lu.se/nrc/bmi_symposium.
- Leading authors review the state-of-the-art in their field of investigation and provide their views and perspectives for future research
- Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
- All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist
Neuroscientists, psychologists, neurologists
Series Editors
List of Contributors
Preface
Chapter 1: Making the lifetime connection between brain and machine for restoring and enhancing function
Introduction
Methods
Results
Discussion
Chapter 2: Out of the frying pan into the fire—the P300-based BCI faces real-world challenges
Introduction
P300
Classification
BCI applications
Influences on BCI performance
Nonvisual P300-based BCI systems
BCI faces the real-world challenge: user experiences with state-of-the-art technology
Conclusion
Chapter 3: Toward a whole-body neuroprosthetic
Introduction
Whole-body neuroprosthetic
BMI components
Large-scale neuronal recordings
BMI decoders
Bimanual control
Bipedal locomotion
Posture and balance
Functional electrical stimulation
Sensorized neuroprosthetic
A whole-body exoskeleton
Chapter 4: Biocompatible multichannel electrodes for long-term neurophysiological studies and clinical therapy—Novel concepts and design
The physiological state
State of the art
A widened concept of biocompatibility
Novel electrode constructs and implantation procedures
Concluding remarks
Chapter 5: Deep brain stimulation
Deep brain stimulation: A genuine brain-device interface
New brain electrode interfaces
Three-dimensional array of electrodes: 3D high-frequency stimulation for field shaping
From DBS to ECoG recording: Brain–machine interface neuroprosthetics for deficit compensation
Conclusion
Chapter 6: Deep brain stimulation
Introduction
Conclusion
Chapter 7: Development of neuromodulation treatments in a large animal model—Do neurosurgeons dream of electric pigs?
Introduction
The Göttingen minipig as a neurobiological research animal
Neuroimaging in the Göttingen minipig
Neurosurgery in the Göttingen minipig
Neural and stem cell transplantation in the Göttingen minipig
Deep brain stimulation in the Göttingen minipig
Spinal cord stimulation in the Göttingen minipig
Conclusion and perspectives
Chapter 8: A few examples of the contribution of animal research in rodents for clinical application of deep brain stimulation
Introduction
Nonmotor functions in PD
DBS for psychiatric disorders
General conclusion
Chapter 9: Cochlear implants
Introduction
Present-day cochlear implants
Importance of brain function in determining outcomes
A “top-down” or “cognitive neuroscience” approach to implant designs
Questions raised by the top-down approach
Chapter 10: Multimodal, longitudinal assessment of intracortical microstimulation
Introduction
Background
Experimental overview
Behavioral thresholds
Impedance
Histology
Conclusion and future work
Chapter 11: The functional consequences of chronic, physiologically effective intracortical microstimulation
Introduction
Methods
Results
Discussion
Chapter 12: Reducing surface area while maintaining implant penetrating profile lowers the brain foreign body response to chronically implanted planar silicon microelectrode arrays
Introduction
Methods
Results
Discussion
Conclusion
Chapter 13: Can histology solve the riddle of the nonfunctioning electrode?
General background
Implant size
Fixation mode
Functional distance
Implantation time
Implant size versus fixation mode over time
Relation between neurons and reactive cell capsule
Strategies for a tethered design
Conclusions
Chapter 14: Changes in CNS structures after spinal cord lesions
Reorganization of cortical areas after incomplete SCI
Reorganization of descending pathways after incomplete SCI
Changes in the spinal circuitry after SCI
Chapter 15: Modeling the potentiality of spinal-like circuitry for stabilization of a planar arm system
Introduction
Methods
Results
Discussion
Chapter 16: Advances in the use of electrical stimulation for the recovery of motor function
Introduction
Command channel for the MNP
Physiological-like electrical stimulation
Artificial control for MNPs: Cloning biological control
Sensor systems
Conclusions
Chapter 17: Intraspinal microstimulation for the recovery of function following spinal cord injury
Introduction
Use of intraspinal microstimulation for restoring leg movements
The movements recruited by ISMS
The stability of ISMS implants
Moving toward clinical application
Conclusions
Chapter 18: Interfacing neurons with carbon nanotubes:
Introduction
The biocompatibility of CNT-based substrates and the impact of CNTs on nerve cell signaling
CNTs as interfaces for neuronal stimulation and recording: improving electrode performance by CNTs
The impact of CNTs on neuronal morphology and growth
Conclusions
Chapter 19: Nanomodified surfaces and neurite outgrowth
Introduction
Methods
Results and discussion
Conclusions
Chapter 20: Direct local polymerization of poly(3,4-ethylenedioxythiophene) in rat cortex
Introduction
Materials and methods
Results and discussion
Conclusions
Subject Index
Volume in series
- Edition: 1
- Latest edition
- Volume: 194
- Published: October 12, 2011
- Language: English
JS
Jens Schouenborg
Affiliations and expertise
Lund University, SwedenMG
Martin Garwicz
Affiliations and expertise
Lund University, SwedenND
Nils Danielsen
Affiliations and expertise
Lund University, SwedenRead Brain Machine Interfaces on ScienceDirect