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Elsevier

Bone Disease of Organ Transplantation

  • 1st Edition - December 28, 2004
  • Latest edition
  • Editors: Juliet Compston, Elizabeth Shane
  • Language: English

Bone disease, particularly osteoporosis, has emerged as a common and serious complication of solid organ transplantation. In recent years there have been real advances in our… Read more

Description

Bone disease, particularly osteoporosis, has emerged as a common and serious complication of solid organ transplantation. In recent years there have been real advances in our understanding of the pathogenesis and pathophysiology of bone loss, however treatment studies have been relatively sparse and successful strategies to reduce skeletal morbidity after transplantation remain to be clearly established. Bone Disease of Organ Transplantation provides a unique resource for the many health professionals involved with transplantation of bone disease, both in terms of its scientific background and the management of the disease in clinical practice.

Key features

  • Basic Transplantation and Bone Biology
  • Pathogenesis of Transplantation Related Bone Disease
  • Clinical Features of Transplantation Bone Disease
  • Management

Readership

Clinicians who work with organ transplantation, as well as researchers in the fields of bone biology and tissue engineering

Table of contents

Part I. Basic Transplantation and Bone Biology

1. Principles of Transplantation Immunology

2. Bone Biology: Bone Structure and Remodeling

3. Skeletal Effects of Glucocorticoids: Basic and Clinical Aspects

4. Transplantation Bone Disease Induced by Non-Steroid Immunosuppressants

5. Molecular Effects of Calcineurin Inhibitors

6. Bone and Immune System

Part II. Pathogenesis of Transplantation-Related Bone Disease

7. Fracture Prevalence and Incidence in Solid Organ Transplant Recipients

8. Bone Histomorphometry and Its Application to Transplantation Bone Disease

9. The Role of Parathyroid Hormone in the Evolution of Bone Loss After Organ Transplantation

10. The Role of Hypogonadism in the Evolution of Bone Loss Before and After Cardiac Transplantation

11. Pathogenesis of Transplantation Bone Diseases: A Unifying Hypothesis

Part III. Clinical Features of Transplantation Bone Disease

12. Bone Disease After Kidney Transplantation

13. Histologic Abnormalities of Bone Before and After Kidney Transplantation

14. Bone Disease Following Kidney-Pancreas and Pancreas Transplantation

15. Bone Disease After Liver Transplantation

16. Bone Disease in Patients Before and After Cardiac Transplantation

17. Bone Loss in Patients Before and After Lung Transplantation

18. Transplantation for Cystic Fibrosis: Effect on the Skeleton

19. Bone Diseaes After Bone Marrow Transplantation

20. Osteonecrosis and Organ Transplantation

21. Pediatric Transplant Bone Disease

Part IV. Management

22. Management of Bone Disease in Candidates for Organ Transplant

23. Management: Prevention of Bone Loss After Organ Transplantation

24. Management: Established Osteoporosis in Organ Transplant Receipients

Review quotes

"...a useful and needed review for those involved in the investigation or management of transplant-related bone disease."—Doodys

Product details

  • Edition: 1
  • Latest edition
  • Published: April 14, 2015
  • Language: English

About the editors

JC

Juliet Compston

Affiliations and expertise
Univeristy of Cambridge, United Kingdom

ES

Elizabeth Shane

Affiliations and expertise
Columbia University, New York, New York, USA

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