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Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins
- 1st Edition - January 1, 1980
- Editor: Gebhard Koch
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 4 1 7 5 6 0 - 0
- Paperback ISBN:9 7 8 - 0 - 1 2 - 4 3 1 6 1 8 - 8
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 1 5 4 2 1 - 5
Biosynthesis, Modification, and Processing of Cellular and Viral Polyproteins presents the proceedings of the international conference held in Hamburg-Blankenese on May 27-31,… Read more
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Request a sales quoteBiosynthesis, Modification, and Processing of Cellular and Viral Polyproteins presents the proceedings of the international conference held in Hamburg-Blankenese on May 27-31, 1980. The book discusses topics on polyproteins, polyfunctional proteins, precursor proteins, as well as the differences in synthesis and processing of ACTH/endorphin peptides in primary cultures of anterior and intermediate lobes of the pituitary. The text also presents evidence for a self-cleaving precursor of virus-coded protease, RNA-replicase, and VPg; and the role of Pr180gag-pol in the characterization and genetic analysis of retrovirus maturation.
Contributors
Foreword
Preface
Opening Remarks
Polyproteins-Polyfunctional Proteins-Precursor Proteins
I. Biosynthesis of Precursors
Neuropolypeptides Illustrate a New Perspective in Mammalian Protein Synthesis—The Composite Common Precursor
A. Hypothalamic Precursors
Biosynthetic Precursors of Neurohormones: High Molecular Weight Immunoreactive Forms of Neurophysin:Vasopressin and of Somatostatin
On the Biosynthetic Origin of Neurophysin-Neurohypophyseal Peptide Hormone Complexes
Hypothalamic mRNA-Directed Synthesis of Neuropolypeptides: Immunological Identification of Precursors to Neurophysin II/Arginine Vasopressin and to Neurophysin I/Oxytocin
Efforts Directed Toward an Understanding of the Biosynthesis of the Hypothalamic-Releasing Hormones
Immunological, Enzymological, and Chemical Characterization of a Large Somatostatin-Like Polypeptide
B. Pituitary Precursors
Pro-Opiomelanocortin: A New Concept Issued from ACTH and LPH Biosynthetic Studies
Biosynthesis of the Enkephalins: Precursors and Intermediates
C. Viral Precursors
Synthesis and Maturation of the Vesicular Stomatitis Virus Glycoprotein
II. Processing and Modifications
Differences in Synthesis and Processing of ACTH/Endorphin Peptides in Primary Cultures of Anterior and Intermediate Lobes of the Pituitary
Post-Translational Processing of Pro-ACTH/Endorphin in Rat Pituitary
The Role of the Carbohydrate in the Stabilization, Processing, and Packaging of Pro-ACTH/αMSH-Endorphin in Frog and Mouse Pituitary Neurointermediate Lobes
Polyadenylylation of Reovirus Proteins
Processing of the Influenza Virus Hemagglutinin
Alterations in the Processing and Shedding of Retrovirus Proteins in Friend Erythroleukemia Cells
Murine Leukemia Virus Polyprotein Processing
Processing and Structure of Murine Leukemia Virus Gag and Env Gene-Encoded Polyproteins
Synthesis and Processing of the Internal Structural Proteins of Retroviruses: Site of Synthesis, Evidence for Multiply Charged Species, and Analysis of a Mutant Defective in Processing
Influence of Medium Hyperosmolanty and of Guanidine on the Synthesis and Processing of Poliovirus Proteins
III. Virus-Coded Proteases
Evidence for a Self-Cleaving Precursor of Virus-Coded Protease, RNA-Replicase, and VPg
Protein Synthesis and Cleavage in Picornavirus-Infected Cells
Polyprotein Processing by Avian Viral Protease
IV. Genetic Analysis
Characterization and Genetic Analysis of Retrovirus Maturation: A Role for Pr180gag-po1
VPg: The Genome-Linked Protein of Picornaviruses
Organization of Human Genomic DNA Encoding Pro-Opiomelanocortin
Concluding Remarks: Post Translational Modifications of Proteins in Discrete Subcellular Organelles
Index
- No. of pages: 360
- Language: English
- Edition: 1
- Published: January 1, 1980
- Imprint: Academic Press
- Hardback ISBN: 9780124175600
- Paperback ISBN: 9780124316188
- eBook ISBN: 9780323154215
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