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Biophysical Characterization of Proteins in Developing Biopharmaceuticals
- 2nd Edition - September 1, 2019
- Editors: Damian J. Houde, Steven A. Berkowitz
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 4 - 6 4 1 7 3 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 4 - 6 4 1 7 4 - 8
Biophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure… Read more
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Request a sales quoteBiophysical Characterization of Proteins in Developing Biopharmaceuticals, Second Edition, presents the latest on the analysis and characterization of the higher-order structure (HOS) or conformation of protein based drugs. Starting from the very basics of protein structure, this book explains the best way to achieve this goal using key methods commonly employed in the biopharmaceutical industry. This book will help today’s industrial scientists plan a career in this industry and successfully implement these biophysical methodologies. This updated edition has been fully revised, with new chapters focusing on the use of chromatography and electrophoresis and the biophysical characterization of very large biopharmaceuticals.
In addition, best practices of applying statistical analysis to biophysical characterization data is included, along with practical issues associated with the concept of a biopharmaceutical’s developability and the technical decision-making process needed when dealing with biophysical characterization data.
- Presents basic protein characterization methods and tools applicable to (bio)pharmaceutical research and development
- Highlights the capabilities and limitations of each technique
- Discusses the underlining science of each tool
- Empowers industrial biophysical chemists by providing a roadmap for applying biophysical tools
- Outlines the needs for new characterization and analytical tools in the biopharmaceutical industry
Researchers in academia and corporate laboratories who develop new instrumental methods for characterisation of proteins in general and biopharmaceutical proteins specifically; researchers in industry who develop these proteins and need characterisation methods
- No. of pages: 586
- Language: English
- Edition: 2
- Published: September 1, 2019
- Imprint: Elsevier
- Paperback ISBN: 9780444641731
- eBook ISBN: 9780444641748
DH
Damian J. Houde
SB
Steven A. Berkowitz
Dr. Berkowitz received a B.S. degree in Biology from Fairleigh Dickinson University and a Ph.D. degree in Biochemistry from New York University. He then spent several years as a post-doctoral fellow at Yale University and the NIH. After his post-doctoral work Dr. Berkowitz held various positions at Celanese Research Company, J.T. Baker, and Lederle Laboratories before taking his present position at Biogen Idec.