Biodegradable Metals and Their Medical Applications
- 1st Edition - October 1, 2025
- Author: Yufeng Zheng
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 2 1 3 3 - 0
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 2 1 3 4 - 7
Biodegradable Metals and Their Medical Applications presents an authoritative overview of all aspects of biodegradable metals and their biomedical applications from the defini… Read more
Biodegradable Metals and Their Medical Applications presents an authoritative overview of all aspects of biodegradable metals and their biomedical applications from the definition, criteria, classification and alloying design of biodegradable metals to the mechanical property optimization, degradation control, biological effect, surface treatment, and advanced manufacture technologies of various biodegradable alloying systems. In vitro and in vivo biocompatibility evaluations for each kind of degradable metallic biomaterials are also discussed, and medical devices designed for usage within bone, blood, and other body microenvironments are presented, making this a complete resource for researchers in the fields of materials science and biomedical engineering.
- Provides updated knowledge on the alloying design and microstructure-property relationship of biodegradable metals
- Features state-of-the-art research and development status of various medical devices comprising biodegradable metals
- Reviews mechanical, chemical, and biological interactions between the biodegradable metals and the host, and their spatiotemporal precise bioadapatibility
Advanced students, engineers, researchers and R&D professionals working in the fields of materials science, engineering, and biomedical engineering
1 Definition, criteria and classification of biodegradable metals
1.1 Definition of biodegradable metals
1.2 Criteria for being biodegradable metals
1.2.1 Biodegradability criteria
1.2.2 Biocompatibility criteria
1.3 Classification of biodegradable metals
1.4 General guidance on material design of biodegradable metals
2 Mechanical bioadaptability of biodegradable metals
2.1 Stress-strain behaviour of biodegradable metals under static load
2.1.1 Tension
2.1.2 Compression
2.1.3 Torsion
2.2 Stress-strain behaviour of biodegradable metals under dynamic load
2.2.1 Fatigue in air
2.2.2 Corrosion fatigue in simulated body fluid
2.3 Mechanical property degeneration with time in vivo
2.3.1 Mechanical property degeneration within bone
2.3.2 Mechanical property degeneration within blood vessel
3 Chemical bioadaptability of biodegradable metals
3.1 Degradation mode and rate
3.2 Modelling the degradation behaviour of biodegradable metals
3.3 Controlling/coupling the degradation behaviour of biodegradable metals
3.4 Conceptual idea on “100% completely biodegradable” metals
4 Biological bioadaptability of biodegradable metals
4.1 Metal ions and their bio-functions
4.1.1 metal cations stimulate skeleton interoception
4.1.2 metal ion metabolism in cardiovascular diseases
4.1.3 metal ions and the antibacterial function
4.2 Bioactivity of biodegradable metals and their bioactivity degree
4.3 Biological property degeneration with time in vivo
5 Mg-based biodegradable metals
5.1 Material design and manufacture of biodegradable Mg alloy
5.2 State-of-the-art of the Mg-based biodegradable metals
5.2.1 high purity Mg
5.2.2 Mg–Ca based alloys
5.2.3 Mg–Sr-based alloys
5.2.4 Mg–Zn-based alloys
5.2.5 Mg–Si-based alloys
5.3. State-of-the-art of the Mg-based biodegradable alloy device research
5.3.1. Cardiovascular devices
5.3.2. Orthopedic devices
5.3.3 Other devices
5.4. Challenges and opportunities for Mg-based biodegradable metals
6 Fe-based biodegradable metals
6.1 Material design and manufacture of biodegradable Fe alloy
6.2 State-of-the-art of the Fe-based biodegradable metals
6.2.1 High purity Fe
6.2.2 Fe–Mn based alloys
6.2.3 Nitride Fe
6.3. State-of-the-art of the Fe-based biodegradable metal device research
6.4. Challenges and opportunities for FE-based biodegradable metals
7 Zn-based biodegradable metals
7.1 Material design and manufacture of biodegradable Zn alloy
7.2 State-of-the-art of the Zn-based biodegradable metals
7.2.1 High purity Zn
7.2.2 Zn–Mg based alloys
7.2.3 Zn–Mn-based alloys
7.2.4 Zn–Fe-based alloys
7.2.5 Zn–Li-based alloys
7.3. State-of-the-art of the Zn-based biodegradable alloy device research
7.3.1. Cardiovascular devices
7.3.2. Orthopedic devices
7.3.3 Dental devices
7.4. Challenges and opportunities for Zn-based biodegradable metals
8 Surface treatment of biodegradable metals
8.1 Mechanical treatment
8.2 Physical treatment
8.3 Chemical treatment
8.4 Vitalizing treatment
9 biodegradable metals matrix composites
9.1 Material design and manufacture of biodegradable metals matrix composite
9.2 Mg-based biodegradable metals matrix composites
9.3 Fe-based biodegradable metals matrix composites
9.4 Zn-based biodegradable metals matrix composites
10 biodegradable bulk metallic glasses
10.1 Material design and manufacture of biodegradable bulk metallic glass
10.2 Mg-based biodegradable bulk metallic glasses
10.3 Ca-based biodegradable bulk metallic glasses
10.4 Zn-based biodegradable bulk metallic glasses
10.5 Sr-based biodegradable bulk metallic glasses
11 3D printing of biodegradable metals
11.1 Geometric design
11.2 Powder fabrications
11.3 3D printed Mg alloys
11.4 3D printed Fe alloys
11.5 3D printed Zn alloys
12 thin films of biodegradable metals and their application in transient electronic devices
12.1 Biodegradable magnesium related thin films
12.2 Biodegradable molybdenum related thin films
12.3 Biodegradable tungsten related thin films
12.4 Biodegradable chromium related thin films
12.5 Biodegradable iron related thin films
13 Perspective on future development directions of biodegradable metals
13.1 Usage of biodegradable metals as drugs
13.2 Biodegradable metals with shape memory effects
13.3 Activating biodegradable metals with external fields
1.1 Definition of biodegradable metals
1.2 Criteria for being biodegradable metals
1.2.1 Biodegradability criteria
1.2.2 Biocompatibility criteria
1.3 Classification of biodegradable metals
1.4 General guidance on material design of biodegradable metals
2 Mechanical bioadaptability of biodegradable metals
2.1 Stress-strain behaviour of biodegradable metals under static load
2.1.1 Tension
2.1.2 Compression
2.1.3 Torsion
2.2 Stress-strain behaviour of biodegradable metals under dynamic load
2.2.1 Fatigue in air
2.2.2 Corrosion fatigue in simulated body fluid
2.3 Mechanical property degeneration with time in vivo
2.3.1 Mechanical property degeneration within bone
2.3.2 Mechanical property degeneration within blood vessel
3 Chemical bioadaptability of biodegradable metals
3.1 Degradation mode and rate
3.2 Modelling the degradation behaviour of biodegradable metals
3.3 Controlling/coupling the degradation behaviour of biodegradable metals
3.4 Conceptual idea on “100% completely biodegradable” metals
4 Biological bioadaptability of biodegradable metals
4.1 Metal ions and their bio-functions
4.1.1 metal cations stimulate skeleton interoception
4.1.2 metal ion metabolism in cardiovascular diseases
4.1.3 metal ions and the antibacterial function
4.2 Bioactivity of biodegradable metals and their bioactivity degree
4.3 Biological property degeneration with time in vivo
5 Mg-based biodegradable metals
5.1 Material design and manufacture of biodegradable Mg alloy
5.2 State-of-the-art of the Mg-based biodegradable metals
5.2.1 high purity Mg
5.2.2 Mg–Ca based alloys
5.2.3 Mg–Sr-based alloys
5.2.4 Mg–Zn-based alloys
5.2.5 Mg–Si-based alloys
5.3. State-of-the-art of the Mg-based biodegradable alloy device research
5.3.1. Cardiovascular devices
5.3.2. Orthopedic devices
5.3.3 Other devices
5.4. Challenges and opportunities for Mg-based biodegradable metals
6 Fe-based biodegradable metals
6.1 Material design and manufacture of biodegradable Fe alloy
6.2 State-of-the-art of the Fe-based biodegradable metals
6.2.1 High purity Fe
6.2.2 Fe–Mn based alloys
6.2.3 Nitride Fe
6.3. State-of-the-art of the Fe-based biodegradable metal device research
6.4. Challenges and opportunities for FE-based biodegradable metals
7 Zn-based biodegradable metals
7.1 Material design and manufacture of biodegradable Zn alloy
7.2 State-of-the-art of the Zn-based biodegradable metals
7.2.1 High purity Zn
7.2.2 Zn–Mg based alloys
7.2.3 Zn–Mn-based alloys
7.2.4 Zn–Fe-based alloys
7.2.5 Zn–Li-based alloys
7.3. State-of-the-art of the Zn-based biodegradable alloy device research
7.3.1. Cardiovascular devices
7.3.2. Orthopedic devices
7.3.3 Dental devices
7.4. Challenges and opportunities for Zn-based biodegradable metals
8 Surface treatment of biodegradable metals
8.1 Mechanical treatment
8.2 Physical treatment
8.3 Chemical treatment
8.4 Vitalizing treatment
9 biodegradable metals matrix composites
9.1 Material design and manufacture of biodegradable metals matrix composite
9.2 Mg-based biodegradable metals matrix composites
9.3 Fe-based biodegradable metals matrix composites
9.4 Zn-based biodegradable metals matrix composites
10 biodegradable bulk metallic glasses
10.1 Material design and manufacture of biodegradable bulk metallic glass
10.2 Mg-based biodegradable bulk metallic glasses
10.3 Ca-based biodegradable bulk metallic glasses
10.4 Zn-based biodegradable bulk metallic glasses
10.5 Sr-based biodegradable bulk metallic glasses
11 3D printing of biodegradable metals
11.1 Geometric design
11.2 Powder fabrications
11.3 3D printed Mg alloys
11.4 3D printed Fe alloys
11.5 3D printed Zn alloys
12 thin films of biodegradable metals and their application in transient electronic devices
12.1 Biodegradable magnesium related thin films
12.2 Biodegradable molybdenum related thin films
12.3 Biodegradable tungsten related thin films
12.4 Biodegradable chromium related thin films
12.5 Biodegradable iron related thin films
13 Perspective on future development directions of biodegradable metals
13.1 Usage of biodegradable metals as drugs
13.2 Biodegradable metals with shape memory effects
13.3 Activating biodegradable metals with external fields
- Edition: 1
- Published: October 1, 2025
- Language: English
YZ
Yufeng Zheng
Dr. Yufeng Zheng is a Professor of Biomaterials at the School of Materials Science and Engineering, Peking University, China. He received his BSc (1993) degree in Metallic materials and Heat Treatment at the Harbin Engineering University and PhD (1998) degree in Materials Science at the Harbin Institute of Technology, China. His research interests include the development of new kinds of metallic biomaterials (biodegradable metals including Mg alloys, Fe alloys and Zn alloys, Bulk metallic glass, etc.), surface modification of metallic biomaterials, development of interventional therapy and minimal invasive therapy devices (stent, occlude, etc.), and optimal design and evaluation of biomedical devices using finite element analysis.
Dr. Zheng is the principal investigators of over 50 projects, owner of several Chinese invention patents, and has published numerous peer-reviewed articles in prominent Journals. He is the Founding Editor-in-Chief of Bioactive Materials (KeAi), Editor of Materials Letters (Elsevier), and Vice Editor-in-Chief of Journal of Materials Science & Technology (Elsevier).
Affiliations and expertise
Professor, School of Materials Science and Engineering, Peking University, China