Bioactive Microbial Metabolites

Scope and Challenges

1st Edition - May 23, 2024
Editors: Vaibhav Mishra, Jitendra Mishra, Naveen Kumar Arora
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 8 5 6 8 - 7
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 8 5 6 9 - 4

Bioactive Microbial Metabolites: Scope and Challenges not only focuses on the identification, separation and purification of bioactive metabolites, the book also provides an unders… Read more

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Bioactive Microbial Metabolites: Scope and Challenges not only focuses on the identification, separation and purification of bioactive metabolites, the book also provides an understanding of the metabolic pathways for bioactive metabolites production that play an important role in modern healthcare as frontline treatments for many diseases. This is a valuable reference for research students, academicians and scientists in environmental microbiology and biotechnology, and for industry personnel related to microbiology/ biotechnology. The science discussed herein plays an important role in expanding the market of antibiotics, food and agriculture but also offers eco-friendly, safer and profitable solutions to respective industries.

Cover image
Title page
Table of Contents
Copyright
List of contributors
Chapter 1. Microbial secondary metabolites and their roles in biocontrol of phytopathogens
Abstract
1.1 Introduction
1.2 Primary and secondary metabolites
1.3 Biological control agents
1.4 Fungal secondary metabolites
1.5 Genus Bacillus for biological control of phytopathogens
1.6 Genus Pseudomonas for biological control of phytopathogens
1.7 Conclusion
Acknowledgment
Conflict of Interest
References
Chapter 2. Microbial metabolites with biological control activity
Abstract
2.1 Introduction
2.2 Lytic enzymes
2.3 Antibiotics
2.4 Endotoxins
2.5 Siderophores
2.6 Bacteriocins
2.7 Volatile organic compounds
2.8 Perspectives
2.9 Conclusion
References
Chapter 3. Role of rhizobial metabolites in control of soil-borne phytopathogenic fungi
Abstract
3.1 Introduction
3.2 Rhizobium–legume interactions and biological nitrogen fixation
3.3 Rhizobia as a biocontrol agent against fungal phytopathogens
3.4 Biocontrol mechanism of rhizobia
3.5 Future prospective and conclusion
References
Further reading
Chapter 4. Agriculturally important microbial secondary metabolites
Abstract
4.1 Introduction
4.2 Metabolites from microbes
4.3 VOCs in microbe–microbe interaction
4.4 Bacterial metabolites with insecticidal properties
4.5 Conclusion
References
Chapter 5. Microbial metabolites and bioactive compounds from fermented fruit waste
Abstract
5.1 Introduction
5.2 Potential use of fruit waste
5.3 Fermentation of fruit waste stream
5.4 Improvement of extractable bioactive compounds
5.5 Extraction of bioactive compounds
5.6 Encapsulation of bioactive compounds
5.7 Conclusion
References
Chapter 6. Fungal extracellular carboxylic acids associated with ore mining: a wide perspective for the future
Abstract
6.1 Introduction
6.2 Citric acid
6.3 Itaconic acid
6.4 Fumaric acid
6.5 Malic acid
6.6 Gluconic acid
6.7 Lactic acid
6.8 Oxalic acid
6.9 Alpha-ketoglutaric acid
6.10 Filamentous fungi as bioleaching agents
6.11 Solubilization mechanisms in biohydrometallurgy
6.12 Fungal organic acids in the hydrometallurgy of atmospheric leaching of laterites
6.13 Conclusion
References
Chapter 7. Chitinase enzyme: sources and application
Abstract
7.1 Introduction
7.2 Structure of chitinase
7.3 Sources of chitinase
7.4 Chitinase production
7.5 Applications of chitinases
7.6 Conclusion
References
Chapter 8. Microbial mannanases and their biotechnological applications
Abstract
8.1 Introduction
8.2 Mannan degrading enzymes and their sources
8.3 Mode of action of mannanases
8.4 Microbial source of β-mannanase
8.5 Biotechnological applications of β-mannanases
8.6 Conclusion
References
Chapter 9. Kojic acid: history, properties, biosynthesis, and applications
Abstract
9.1 History
9.2 Physico-chemical properties of kojic acid
9.3 Aspergillus as a producer of kojic acid
9.4 Derivatives of kojic acid
9.5 Applications of kojic acid
9.6 Future directions and concluding remarks
References
Chapter 10. Bioactive peptides derived from milk: formation and functional benefits
Abstract
10.1 Introduction
10.2 Mechanisms for bioactive peptide formation
10.3 Functional effects of milk-derived bioactive peptides
10.4 Lactic acid bacteria (LAB) as source of bioactive peptides
10.5 Conclusion
References
Chapter 11. Insights into the challenges and resolutions in the bacterial fermentation process
Abstract
11.1 Introduction
11.2 Brief history of fermentation
11.3 Bacterial fermentation processes
11.4 Challenges in bacterial fermentation processes
11.5 Conclusions
References
Chapter 12. Microbial protease: an update on sources, production methods, and applications
Abstract
12.1 Introduction
12.2 Classification of protease
12.3 Source of microbial protease
12.4 Production of protease
12.5 Stability of protease
12.6 Application of microbial protease enzyme
12.7 Conclusion
References
Chapter 13. Microbial metabolites with anticancerous properties
Abstract
13.1 Introduction
13.2 Algae metabolites
13.3 Bacterial metabolite
13.4 Fungal metabolites
13.5 Protozoal metabolites
13.6 Regulatory concerns
13.7 Conclusion
References
Further reading
Chapter 14. Underexplored groups of soil microorganisms: a treasure house for bioactive metabolites with therapeutic value
Abstract
14.1 Introduction
14.2 Lineages of novel soil bacteria producing secondary metabolites
14.3 Biosynthetic gene clusters for secondary metabolites production by the soil microorganisms
14.4 Bioactive compounds from soil bacteria and their therapeutic value
14.5 Underexplored soil fungi produce novel bioactive secondary metabolites
14.6 Conclusion
References
Chapter 15. Use and applications of bioactive microbial metabolites in human health
Abstract
15.1 Introduction
15.2 Microbial metabolites
15.3 Sources of microbial metabolites
15.4 Application of bioactive microbial metabolites
15.5 New approaches for bioactive metabolite-based drugs discovery
15.6 Conclusion
References
Index

Vaibhav Mishra

Dr. Vaibhav Mishra is currently an Assistant Professor-III at the Institute of Microbial technology, Amity University, U. P. India. He earned his PhD in Applied Microbiology from Banaras Hindu University, Varanasi, India. His expertise in microbiology and gastroenterology. He was previously a Post-Doctoral Researcher in the Department of Neurology at the University of Missouri in Columbia, Missouri, USA. Before joined University of Missouri, He worked as Senior Research Associate at the University of Johannesburg, South Africa. Dr. Mishra was selected as one of the twelve young biomedical scientists for the prestigious 2019 preceptorship program in Seoul, South Korea among all over young scientists of Asia. In the same year, he was also elected as a Fellow of the Environmental & Biological society (FEBS), one of the most esteemed and oldest societies of India. Moreover, he was the recipient of the “Young Scientist Award” in 2017 by ISGBRD for excellent performance in research. Dr. Mishra is the Assistant Editor of Environmental Sustainability and serves as a reviewer for several reputed international peer-reviewed journals. He has published many research papers in acclaimed journals and has authored two books, book chapters as well as review articles.

Affiliations and expertise

Assistant Professor, Institute of Microbial Technology, Amity University, U. P. India

Jitendra Mishra

Jitendra Mishra, Ph.D. (Agricultural Microbiology) has qualified ASRB-NET. He completed his master’s degree in the Environmental Microbiology (with Gold Medal) from Babasaheb Bhimrao Ambedkar University, Lucknow. He gathered a comprehensive experience in terms of research as well as teaching. He has worked as Assistant Professor (Guest) in the Department of Environmental Microbiology, Babasaheb Bhimrao Ambedkar University, Lucknow. He is also holding the post of Assistant Editor in the journal Environmental Sustainability published by Springer Nature. He has published his research finding in the form of research articles, reviews, book chapters, and opinion in several journals of repute. He has also published an edited book.

Affiliations and expertise

Project Coordinator, Science Technology and Innovation Hub Project, Catalyzed and Supported by DST-SEED Babasaheb Bhimrao Ambedkar University (a Central University), Lucknow, Uttar Pradesh, India

Naveen Kumar Arora

Naveen Kumar Arora, Ph.D. is a renowned researcher in the field of Environmental Microbiology and Biotechnology. His specific area of research is rhizosphere biology and plant growth-promoting rhizobacteria (PGPR). He has more than 80 research papers published in premium international journals. He is the editor of 25 books published by Springer Nature. He is member of several national and international societies, in the editorial board of 4 journals and reviewer of several international journals. He is Editor-in-Chief of the journal Environmental Sustainability published by Springer Nature and Series Editor of book series Microorganisms for Sustainability. He has been an advisor to 11 doctoral students. He has also received awards for excellence in research by the Honourable Governor of Uttar Pradesh, India, Asian PGPR Society, and Samagra Vikas Welfare Society. He is Fellow of International Society for Environmental Botanists and delivered talks as Key Note and Plenary Speaker in conferences around the world. He has collaborations with researchers in various countries including Germany, Uzbekistan, USA, Turkey, etc. Although an academician and researcher by profession, he has a huge obsession for the wildlife and its conservation and has authored a book, Splendid Wilds. He is President of Society for Conservation of Wildlife and is also Secretary of Society for Environmental Sustainability

Affiliations and expertise

FISEB, Professor and Dean, School of Earth and Environmental Sciences, Babasaheb Bhimrao Ambedkar University (a Central University), Lucknow, Uttar Pradesh, India

Life Sciences

Physical Sciences & Engineering

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Bioactive Microbial Metabolites

Scope and Challenges

Purchase options

Institutional subscription on ScienceDirect

Vaibhav Mishra

Jitendra Mishra

Naveen Kumar Arora