Skip to main content

Benzel's Spine Surgery, 2-Volume Set

Techniques, Complication Avoidance and Management

  • 6th Edition - July 30, 2026
  • Latest edition
  • Editors: Michael P. Steinmetz, Sigurd H. Berven, Edward C. Benzel
  • Language: English

Spinal disorders are a priority for healthcare systems internationally. Offering unparalleled, comprehensive coverage of the pathogenesis, evaluation and management of spinal… Read more

Purchase options

Description

Spinal disorders are a priority for healthcare systems internationally. Offering unparalleled, comprehensive coverage of the pathogenesis, evaluation and management of spinal disorders, Benzel’s Spine Surgery: Techniques, Complication Avoidance, and Management, 6th Edition, remains the definitive text in this challenging field. Written and edited by world-renowned experts, this two-volume masterwork covers everything a practicing spine surgeon, non-operative provider, and trainee needs to know—from fundamentals, biomechanics, applied anatomy, instrumentation, and pathophysiology of spinal disorders to all types of spine techniques, motion preservation strategies, non-surgical management, complication avoidance and management, and controversies. Nearly 200 fully revised, well-illustrated chapters keep you up to date with the latest advancements in spine surgery.

"This book is a must-have and a gold standard in textbooks on spine surgery…. Compared to other textbooks, the thoroughness, variety of information and resources, and in-depth expert discussion of topics is unique… 5 Stars!" —Doody's Review Service, review of the previous edition

Key features

  • Shares the knowledge and expertise of an outstanding editorial board, including Dr. Edward C. Benzel, Emeritus Chairman of Neurosurgery at Cleveland Clinic, who has been called “the father of modern spine surgery.”
  • Focuses on both pathophysiology and surgical treatment of spine disease, with an increased emphasis on minimally invasive surgery
  • Offers new coverage of practical applications of AI tools and robotics; regenerative medicine; up-to-date biological considerations; restorative approaches to the spine; therapeutic injections; pathology regarding operative surgery and non-operative surgery; and interventional strategies
  • Includes more procedural videos, new and expanded content throughout, and additional case examples and diagnostic pearls, as well as Key Points boxes at the top of each chapter and algorithms to help streamline the decision-making process
  • Features contributions from experts in multiple disciplines, including neurosurgeons and orthopaedic surgeons, physiatrists, oncologists, and radiologists to present a truly comprehensive and evidence-based approach to spinal disorders
  • Contains more than 1,500 high-quality illustrations for optimal visual guidance
  • An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud. Additional digital ancillary content may publish after the publication date

Readership

Neurosurgeons, spine specialists

Table of contents

VOLUME I

Part 1: Fundamentals of the Spine

Section 1.1: Implant Properties

Chapter 1: History of Spine Surgery
Chapter 2: History of Spine Biomechanics
Chapter 3: History of Spinal Instrumentation: The Modern Era
Chapter 4: Functional Anatomy of the Spine
Chapter 5: Biomechanical Modeling of the Spine
Chapter 6: The Intervertebral Disc: Anatomy, Physiology, and Aging
Chapter 7: Muscles and the Spine: Dynamic Stabilization
Chapter 8: Bone Physiology and Osteoporosis
Chapter 9: Applied Anatomy of the Thoracolumbar Spine
Chapter 10: Fundamentals of Spinal Alignment and Balance: Key Radiographic Measurements and a Practical Guide to Understanding Spinal Deformity and Alignment
Chapter 11: Applied Anatomy of the Spinal Cord
Chapter 12: Molecular and Anatomic Mechanisms of Nerve Root, Spinal Nerve, and Peripheral Nerve Injury
Chapter 13: Spine Fusion: Biology and Biomechanics
Chapter 14: Complications in Spine Surgery: Expected Rates and Classification

Section 1.2: Biomechanics and Biology
Chapter 15: Osteointegration: The Bone and Implant Interface
Chapter 16: Biomechanics and Implant Materials: The Anterior Column
Chapter 17: Biomechanics and Implant Materials: The Posterior Column
Chapter 18: Biomechanics of Motion Preservation Techniques
Chapter 19: Biologic Response to Spinal Instrumentation Particulate Wear Debris–Emphasis on Implant Wear Degradation, and Breakage
Chapter 20: Tribology and Material Contact Science in Spine Surgery: Implications for Implant Design

Part 2: Pathophysiology of Spinal Disorders

Section 2.1: Pathophysiology of Congenital and Developmental Disorders

Chapter 21: Spinal Cord Dysraphisms and Myelodysplasia
Chapter 22: Congenital Spinal Deformity
Chapter 23: Early-Onset Scoliosis
Chapter 24: Late-Onset Idiopathic Scoliosis
Chapter 25: Scheuermann Disease
Chapter 26: Developmental Spondylolisthesis
Chapter 27: Craniovertebral Junction and Atlantoaxial Alterations
Chapter 28: Congenital and Developmental Deformities of the Cervical Spine
Chapter 29: Dural and Meningeal Pathologies
Chapter 30: Tarlov Cysts
Chapter 31: Chiari Malformations and Syringomyelia

Section 2.2: Pathophysiology of Degenerative Disorders
Chapter 32: Pathophysiology of Intervertebral Disc Degeneration and Pain
Chapter 33: Pathophysiology of Cervical Spondylosis, Radiculopathy, and Myelopathy
Chapter 34: Pathophysiology of Thoracic Spondylosis, Radiculopathy, and Myelopathy
Chapter 35: Amyloid Deposition Syndromes

Section 2.3: Deformity
Chapter 36: Deformity in the Cervical Spine
Chapter 37: Pathophysiology, Evaluation, and Management of Adult Degenerative Scoliosis
Chapter 38: Surgical Treatment for Lumbar Spondylolisthesis

Section 2.4: Pathophysiology of Traumatic Disorders
Chapter 39: Neuromuscular Disorders in the Pediatric Spine
Chapter 40: Neuromuscular Disorders and Deformity in the Adult Spine
Chapter 41: Occipitocervical Injuries
Chapter 42: Subaxial Cervical Spine Injuries
Chapter 43: Thoracic and Lumbar Spine Injuries
Chapter 44: Peripheral Nerve Injury
Chapter 45: Spinal Cord Injury
Chapter 46: Spinal Injuries in Sports

Section 2.5: Pathophysiology of Inflammatory and Infectious Disorders
Chapter 47: Rheumatoid Arthritis
Chapter 48: Ankylosing Spondylitis and Other Disorders
Chapter 49: Ossification of the Posterior Longitudinal Ligament
Chapter 50: Primary Infections of the Spine
Chapter 51: Secondary Infections of the Spine

Section 2.6: Pathophysiology of Neoplastic Disorders
Chapter 52: Primary Tumors of the Spine
Chapter 53: Metastatic Tumors of the Spine
Chapter 54: Intradural Extramedullary Spine Tumors
Chapter 55: Intramedullary Spinal Cord Lesions
Chapter 56: Tumors of the Peripheral Nerve Including Brachial Plexus

Section 2.7: Pathophysiology of Syndromic Disorders Affecting the Spine: Connective Tissue and Vascular
Chapter 57: Spinal Disorders Associated With Connective Tissue Disorders
Chapter 58: Osteoporosis, Osteomalacia, and Metabolic Bone Disease
Chapter 59: Vascular Malformations of the Spine

Section 2.8: Pathophysiology of Postoperative Spinal Disorders
Chapter 60: Postoperative Spinal Disorders—Cervical
Chapter 61: Postoperative Spinal Deformity
Chapter 62: Adjacent Segment Degeneration and Disease of the Cervical Spine
Chapter 63: Adjacent Segment Degeneration and Disease of the Lumbar Spine
Chapter 64: Proximal and Distal Junctional Kyphosis and Failure

Part 3: Evaluation of Patients With Spinal Disorders

Chapter 65: Physical and Neurological Examination
Chapter 66: Sagittal Spinal Alignment: An Evolutionary Perspective
Chapter 67: Spinal Alignment: Significance and Preoperative Planning
Chapter 68: Overview of Imaging Procedures Available for Spinal Diagnosis
Chapter 69: Electrodiagnostic Studies
Chapter 70: Differential Diagnosis of Surgical Disorders of the Spine
Chapter 71: Patient Selection for Spine Surgery: Preoperative Optimization
Chapter 72: Evaluation of the Aging Patient
Chapter 73: Preoperative Evaluation of Psychosocial Aspects and Work-Related Issues
Chapter 74: Preoperative Evaluation of Patients With Tumors Affecting the Spine
Chapter 75: Measuring Preoperative Health-Related Quality of Life: What Metrics Matter

VOLUME II

Part 4: Management of Spinal Disorders

Section 4.1: Nonoperative Approaches

Chapter 76: Rehabilitation and Interventions in Management of Spinal Disorders
Chapter 77: Spine Injections
Chapter 78: Cognitive Behavioral Therapy and Back Pain
Chapter 79: Regenerative Strategies and Intervertebral Disc Degeneration
Chapter 80: Neuromodulation and Rehabilitative Interventions for the Spine
Chapter 81: Pain Management: Opioids and Alternatives

Section 4.2: Operative Management of Spinal Disorders: Overview and Principles
Chapter 82: Fundamentals of Spine Surgery
Chapter 83: Perioperative Management Protocols: Enhanced Recovery After Surgery
Chapter 84: Surgical Incisions, Positioning, and Retraction
Chapter 85: Intraoperative Imaging Protocols
Chapter 86: Anesthesia for Spine Surgery and the Prevention of Complications
Chapter 87: Intraoperative Neurophysiologic Monitoring in Routine and Complex Surgery
Chapter 88: Perioperative Management of Blood Loss in Complex Spine Surgery
Chapter 89: Intraoperative Crisis Management in Spine Surgery: What to Do When Things Go Bad
Chapter 90: Biologics in Spine Fusion Surgery
Chapter 91: Common Complications in Spine Surgery: Pseudarthrosis
Chapter 92: Postoperative Medical Complications
Chapter 93: Preventing Postoperative Infections: An Evidence-Based Approach
Chapter 94: Neurological Complications of Common Spine Operations
Chapter 95: Cerebrospinal Fluid Leak: Repair and Outcomes
Chapter 96: Arachnoiditis and Syringomyelia
Chapter 97: Posttraumatic and Idiopathic Syringomyelia
Chapter 98: Vascular and Soft Tissue Complications
Chapter 99: Thromboembolic Disease in Spine Surgery
Chapter 100: Postoperative Spinal Deformities
Chapter 101: Revision of Cervical Disk Arthroplasty
Chapter 102: Readmissions and Reoperation in Spine Surgery: The Use of Predictive Analytics

Section 4.3: Operative Management of Spinal Disoders: Occipital and Cervical
Chapter 103: Cervical Spine Construct Design
Chapter 104: Occipitocervical Spine Approaches for Decompression
Chapter 105: Upper Cervical Screw Fixation Techniques
Chapter 106: Endoscopic and Transnasal Approaches to the Craniocervical Junction
Chapter 107: Cervical Spine and Cervicothoracic Junction— Posterior
Chapter 108: Posterior Cervical Decompressions: Cervical Laminectomy and Laminoforaminotomy
Chapter 109: Cervical Laminoplasty
Chapter 110: Dorsal Subaxial Cervical Instrumentation Techniques
Chapter 111: Posterior Percutaneous and Minimally Invasive Approaches to Decompression and Arthrodesis of the Cervical Spine
Chapter 112: Cervical Spine and Cervicothoracic Junction— Anterior Approach
Chapter 113: Anterior Cervical Discectomy and Corpectomy
Chapter 114: Management of Soft Cervical Disc Herniation: Controversies and Complication Avoidance
Chapter 115: Anterior Subaxial Cervical Fixation and Fusion Techniques
Chapter 116: Cervical Total Disc Arthroplasty
Chapter 117: Combined Ventral-Dorsal Surgery

Section 4.4: Operative Management of Spinal Disorders: Thoracolumbar
Chapter 118: Thoracic and Lumbar Spine Construct Design
Chapter 119: Posterior Approaches to the Thoracic Spine
Chapter 120: Anterior and Lateral Approaches to the Thoracic Spine
Chapter 121: Posterolateral Thoracolumbar Fusion
Chapter 122: Transforaminal Lumbar Interbody Fusion
Chapter 123: Posterior Thoracolumbar Fixation Techniques
Chapter 124: Midline Lumbar Interbody Fusion With Cortical-Bone-Trajectory Pedicle Screw Placement
Chapter 125: Dorsal Semirigid Stabilization
Chapter 126: Lumbar Total Disc Arthroplasty
Chapter 127: Minimally Invasive Spinal Decompression and Stabilization Techniques: Philosophy and Rationale
Chapter 128: Posterior Approaches to the Lumbar Spine: Minimally Invasive Decompression
Chapter 129: Endoscopic Approaches to the Cervical Spine
Chapter 130: Endoscopic Surgical Approaches to the Lumbar Spine
Chapter 131: Posterior Approaches to the Lumbar Spine: Minimally Invasive Fusion
Chapter 132: Anterior Lumbar Interbody Fusion
Chapter 133: Minimally Invasive Surgery Approaches: Anterior and Anterolateral Lumbar Spine Interbody Fusion
Chapter 134: Complex Lumbosacropelvic Fixation Techniques
Chapter 135: Spinopelvic Fixation for Posterior Pelvic and Lumbosacral Injuries
Chapter 136: Spinal Augmentation for Vertebral Compression Fractures

Part 5: Operative Management of Specific Disorders of the Spine

Section 5.1: Degenerative Pathologies

Chapter 137: Indications for Spine Fusion for Axial Pain
Chapter 138: Cervical Disc Herniation
Chapter 139: Cervical Spondylotic Myelopathy
Chapter 140: Lumbar Disc Herniation
Chapter 141: Thoracic Discectomy
Chapter 142: Degenerative Spondylolisthesis
Chapter 143: Spondylolysis and Low-Grade Spondylolisthesis
Chapter 144: Sacroiliac Joint Pain

Section 5.2: Spinal Deformity
Chapter 145: Surgical Principles for Spinal Deformity
Chapter 146: An Approach for Treatment of Complex Adult Spinal Deformity
Chapter 147: Pediatric Spinal Deformity
Chapter 148: Cervicothoracic Deformity: The Role of Anterior Surgery
Chapter 149: The Role of Anterior Surgery for Thoracolumbar Deformity
Chapter 150: Anterior Column Realignment in Deformity
Chapter 151: Posterior-Based Osteotomies for Management of Spinal Deformity
Chapter 152: Minimally Invasive Approaches to Spinal Deformity
Chapter 153: Surgical Management of High-Grade Dysplastic Spondylolisthesis
Chapter 154: Failed Back Surgery Syndrome

Section 5.3: Tumors of the Spine
Chapter 155: Oncological Approaches and Outcomes for Primary Spine Tumors
Chapter 156: Staging, Classification, and Oncologic Approaches for Metastatic Tumors Involving the Spine
Chapter 157: Tumors at the Foramen Magnum and Craniocervical Junction
Chapter 158: Cervicothoracic Junction Tumors
Chapter 159: Thoracic and Thoracolumbar Spinal Tumors— Regional Challenges
Chapter 160: Sacral Tumors: Regional Challenges
Chapter 161: Radiosurgery for Spinal Tumors

Section 5.4: Trauma and the Spine
Chapter 162: The Acute Management of Traumatic Spinal Cord Injury and Polytrauma
Chapter 163: Timing of Surgery Following Traumatic Spinal Cord Injury
Chapter 164: Medical Management of Adult and Pediatric Spinal Cord Injury
Chapter 165: Spinal Traction
Chapter 166: Medical Management of Fractures Without Spinal Cord Injury
Chapter 167: Anterior Surgery for Cervical Trauma
Chapter 168: Posterior Surgery for Cervical Trauma
Chapter 169: Surgical Approaches to Thoracolumbar Trauma
Chapter 170: Surgical Approaches for Sacral Fractures and Sacropelvic Injuries
Chapter 171: Rehabilitation and Recovery After Spinal Cord Injury
Chapter 172: Regenerative Techniques of Spinal Cord Injury

Section 5.5: General Surgical Technique
Chapter 173: Harvest of Autograft for Spinal Fusion
Chapter 174: Vascularized Bone Grafts in Spine Surgery
Chapter 175: Navigation and Robotics in Spine Surgery

Part 6: Evidence Development and Guidance of Informed Choice for Optimal Outcomes

Chapter 176: Big Data in Healthcare
Chapter 177: Spine Registries
Chapter 178: Conflicts of Interest in Spine Surgery
Chapter 179: Art of the Clinical Trial
Chapter 180: Meaningful Retrospective Analysis
Chapter 181: Art and Science of Guideline Formation
Chapter 182: Appropriate Use Criteria in Spine Surgery
Chapter 183: Precision Medicine: Artificial Intelligence Applied to Evaluation and Management of Spinal Disorders
Chapter 184: Healthcare Reform and Spine Surgery: Economic Impact and the Shift to Value-Based Care
Chapter 185: Development of New Technologies in Spine Surgery

Review quotes

Review of the previous edition:
"This book is a must-have and a gold standard in textbooks on spine surgery. Compared to previous editions, there are multiple updates with new guidelines and research, especially in regard to the minimally invasive, novel, and robotic approaches. Therefore, the update's new set of figures and online materials make it a very worthwhile update and edition. Compared to other textbooks, the thoroughness, variety of information and resources, and in-depth expert discussion of topics is unique, making it a must-have reference book for spine surgery." -©Doody’s Review Service, 2022, Morteza Sadeh, MD PhD (University of Illinois at Chicago College of Medicine) Doody's Score: 5 Stars!

Product details

  • Edition: 6
  • Latest edition
  • Published: October 27, 2026
  • Language: English

About the editors

SB

Sigurd H. Berven

Affiliations and expertise
Professor in Residence and Chief of Spine Service, Department of Orthopaedic Surgery, University of California, San Francisco, San Francisco, California

EB

Edward C. Benzel

Affiliations and expertise
Emeritus Chairman, Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio