LIMITED OFFER
Save 50% on book bundles
Immediately download your ebook while waiting for your print delivery. No promo code needed.
Basic Science in Obstetrics and Gynaecology
A Textbook for MRCOG Part 1
- 5th Edition - March 2, 2023
- Authors: Phillip Bennett, Catherine Williamson, Lynne Sykes, David A MacIntyre, Peter H Dixon
- Language: English
- Paperback ISBN:9 7 8 - 0 - 7 0 2 0 - 7 4 2 2 - 6
Basic Science in Obstetrics and Gynaecology is an essential one-stop, portable revision tool for candidates preparing for Part 1 of the MRCOG specialist examination. Fully updated… Read more
Purchase options
Institutional subscription on ScienceDirect
Request a sales quoteBasic Science in Obstetrics and Gynaecology is an essential one-stop, portable revision tool for candidates preparing for Part 1 of the MRCOG specialist examination.
Fully updated by experts who are internationally recognised in their fields, the chapters match the syllabus of the exam, combining detailed coverage of the science with related self-assessment questions that you will encounter in the MRCOG.
This book is suitable for doctors specialising in obstetrics and gynaecology who want the best chance possible to pass this difficult exam.
- Covers all topics for the MRCOG Part 1, including basic science and clinical anatomy
- Contains self-assessment SBA questions to consolidate learning
- Includes three mock exam papers enabling you to practice for the exam
- Digital version included
- Cover image
- Title page
- Table of Contents
- Any screen, Any time, Anywhere
- Copyright
- Preface
- Contributors
- Acknowledgements
- 1. Structure and Function of the Genome
- Chapter outline
- Chromosomes
- Gene Structure and Function
- The Central Dogma of Molecular Biology
- Epigenetics
- Mitochondrial DNA
- Studying DNA
- Molecular Biology Techniques
- The ‘Postgenomic’ Era
- The Molecular Basis of Inherited Disease – DNA Mutations
- 2. Clinical Genetics
- Chapter outline
- Chromosome Abnormalities
- Single Gene Disorders
- Multifactorial Inheritance
- Genetic Testing and Interpretation of a Genetic Result
- 3. Embryology
- Chapter outline
- Oogenesis and Spermatogenesis
- Development of the Genital Organs
- Development of the Placenta
- Development of Membranes and Formation of Amniotic Fluid
- 4. Fetal and Placental Physiology
- Chapter Outline
- Introduction
- Fetal Development and Preparation for Birth
- Placental Growth and Development
- Fetal Growth and Growth Restriction
- References
- 5. Applied Anatomy
- Chapter outline
- Introduction
- Body Tissues and Cells
- The Nervous System
- Anatomy of the Brain
- The Lymphatic System
- The Vascular System
- The Arterial System
- The Venous System
- The Musculoskeletal System
- The Fetal Skull
- Relevant Regional Anatomy of the Thorax
- The Abdomen
- The Liver
- The Alimentary Tract
- Retroperitoneal Organs
- The Urinary Tract
- The Pelvis
- The Perineum
- The Ischiorectal Fossae (Fig. 5.25)
- Lateral Pelvic Wall
- Pelvic Organs
- The Rectum
- The Anal Canal
- The Bladder
- The Breast
- 6. Pathology
- Chapter outline
- General Pathological Principles
- Cellular Injury and Death
- Pathology of Gynaecological Tumours
- Pathology of Miscarriage and Gestational Trophoblastic Disease
- Pathology of Common Congenital Abnormalities and Teratogenesis
- Pathology of the Placenta
- 7. Microbiology and Virology
- Chapter outline
- Bacteriology, Mycology and Parasitology
- Laboratory Identification
- Bacteria and Disease
- Killing Bacteria
- Mycology
- Parasites
- Virology
- Viral Nucleic Acid
- Viruses of Importance in Obstetrics and Gynaecology
- References
- 8. Immunology
- Chapter outline
- Introduction
- The Immune System
- Adaptive Immune Systems
- Cells of the Innate Immune System
- Regulation of the Immune System
- The Fetus as an Allograft
- Conclusion
- 9. Biochemistry
- Chapter outline
- Structure and Function of the Normal Cell
- Proteins, Peptides and Amino Acids
- Metabolism
- Catabolism
- Enzymes
- Cell Signalling and Second Messaging
- Biochemistry Exam Notes
- 10. Physiology
- Chapter Outline
- Biophysical Definitions
- Distribution of Water and Electrolytes
- Cellular Transport Mechanisms
- Acid–Base Balance
- Cardiovascular System
- Endothelium in Pregnancy
- Respiration
- Urinary System
- Gastrointestinal Tract
- Liver
- Nervous System
- Blood
- References
- 11. Endocrinology
- Chapter Outline
- Introduction
- Mechanisms of Hormone Action and Second Messenger Systems
- Hormone Types
- Hypothalamus and Pituitary
- Pineal Gland
- Reproductive Hormones
- Puberty
- Leptin
- Pregnancy
- Menopause
- Growth
- Pancreas
- Thyroid
- Adrenal Gland
- Calcium Homeostasis
- 12. Drugs and Drug Therapy
- Chapter outline
- Introduction
- Language of Clinical Pharmacy
- Factors that Influence Drug Action
- Physiological Changes that Affect Drug Metabolism in Pregnancy
- The Placental Barrier
- Some Commonly Used Drugs
- Psychotropic Drugs
- Oral Contraceptives
- Mechanism of Action of the Combined Pill
- Drugs of Choice in Breastfeeding
- Conclusion
- 13. Physics in Obstetrics and Gynaecology
- Chapter Contents
- Introduction
- Physics for Surgery
- Laser
- Imaging
- Ionising Radiation
- Nuclear Medicine
- Ultrasound
- 14. Statistics and Evidence-Based Healthcare
- Chapter Outline
- Introduction
- Some Basic Statistical Principles
- Primary and Secondary Outcomes
- Data Types, Distribution Assumptions and Parametric Tests
- Data Collection and Presentation
- Measures of Outcome, Exposure and Effect
- Equations for Basic Power Calculations
- Acknowledgement
- Recommended Statistics Texts
- 15. Clinical Research Methodology
- Chapter outline
- Introduction
- Types of Clinical Investigation
- The Clinical Research Process
- Registration of Trials
- Data
- Consent, Information and Sponsors
- Trial Steering Committees and Data Monitoring and Ethics Committees
- Review of the Literature
- Amendments and Reports
- Promoting and Maintaining a Trial
- Common Statistical Terms Used in Clinical Trials
- References
- Useful Sources of Information
- 16. Self-Assessment
- Chapter Outline
- Chapter 1: Structure and Function of the Genome Questions
- Chapter 2: Clinical Genetics Questions
- Chapter 3: Embryology Questions
- Chapter 4: Fetal and Placental Physiology Questions
- Chapter 5: Applied Anatomy Questions
- Chapter 6: Pathology Questions
- Chapter 7: Microbiology and Virology Questions
- Chapter 8: Immunology Questions
- Chapter 9: Biochemistry Questions
- Chapter 10: Physiology Questions
- Chapter 11: Endocrinology Questions
- Chapter 12: Drugs and Drug Therapy Questions
- Chapter 13: Physics in Obstetrics and Gynaecology Questions
- Chapter 14: Statistics and Evidence-Based Health Care Questions
- Chapter 15: Clinical Research Methodology Questions
- Mock Exam Papers
- Answers
- Index
- No. of pages: 400
- Language: English
- Edition: 5
- Published: March 2, 2023
- Imprint: Elsevier
- Paperback ISBN: 9780702074226
PB
Phillip Bennett
Affiliations and expertise
Professor of Obstetrics and Gynaecology, Institute of Obstetrics and Gynaecology, Queen Charlotte's and Chelsea Hospital, London, UKCW
Catherine Williamson
Affiliations and expertise
Senior Lecturer in Obstetric Medicine, Institute of Reproductive and Developmental Biology, Imperial College, London, UK