Basic & Applied Concepts of Blood Banking and Transfusion Practices
- 6th Edition - November 12, 2024
- Authors: Paula R. Howard, Wyenona Hicks
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 1 1 3 6 5 - 9
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 1 1 8 5 8 - 6
Master the role of the medical laboratory scientist working in the blood bank and transfusion services! Basic & Applied Concepts of Blood Banking and Transfusion Practices, Si… Read more
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Request a sales quoteMaster the role of the medical laboratory scientist working in the blood bank and transfusion services! Basic & Applied Concepts of Blood Banking and Transfusion Practices, Sixth Edition combines scientific principles with practice tips to engage learners with realistic laboratory experiences. These concepts are delivered through relevant case studies and critical thinking exercises. The text provides an overview of topics including quality and safety, the major blood groups, blood collecting and testing, transfusion reactions, and blood component preparation. Written by Paula Howard and Wyenona “Nonie” Hicks, both experienced Medical Laboratory Scientists and certified as Specialists in Blood Banking (SBB), this text is ideal for students in any Medical Laboratory Science (MLS), Medical Laboratory Technician (MLT), or Blood Bank Technology (BBT) training program, as well as for practicing laboratory and healthcare professionals who wish to train for work in blood banks and transfusion services.
- NEW! Full-color illustrations that break down concepts for enhanced learner comprehension, especially for those who favor visual learning
- NEW! Did You Know?, Case Study, ALERT! What’s the Impact?, and Practice Tips provide important facts and guidelines to prepare you for situations encountered in practice
- NEW! Additional case studies relate to donor qualification and testing, ABO discrepancies, molecular immunohematology techniques, antibody identification, stem cell transplants, and coagulation disorders, offering extra practice in critical thinking development
- NEW! Cell therapy and flow cytometry information, expanded HLA and platelet antigen and antibody material, detailed molecular genetic information in the Rh blood group system chapter, and an expanded molecular genetics section prepare you for the questions you’ll be challenged with on the certification exam
- NEW! End-of-chapter Critical Thinking and Study Questions are keyed to the objectives
- Coverage of current clinical practices includes transplantation and cellular therapy, the HLA system, molecular techniques and applications, automation, blood donor qualification, collection and testing, component manufacturing and transfusion practices, therapeutic phlebotomy and therapeutic apheresis, and antibody identification and special techniques
- Learning features in each chapter break down difficult concepts with outlines, learning objectives, key terms with definitions, special callouts, chapter summaries, basic and challenging case studies, critical thinking exercises, and study questions
- Numerous new, updated, and expanded tables summarize key information and make it easier to compare content. These will certainly continue to provide excellent references for graduates practicing in blood banks and transfusion services
- Updated illustrated blood group antigen toolbars show at a glance the ISBT symbol, number, clinical significance, reactions to chemical treatments, and more for antibodies
- Comprehensive glossary provides definitions to key terms throughout the text
- Expanded online resources for students and instructors include additional study/test questions and case studies
Clinical Laboratory Science (CLS/MLS) students, Clinical Laboratory Technician (CLT/MLT) students
- Title of Book
- Cover image
- Title page
- Table of Contents
- Any screen, Any time, Anywhere
- Copyright
- Dedication
- Reviewers and Collaborators
- Preface
- Introduction
- Part I: Quality and Safety Issues
- 1. Quality Management, Regulation, and Safety in Blood Banks and Transfusion Services
- CHAPTER OUTLINE
- KEY TERMS
- SECTION 1: INSPECTING AGENCIES
- SECTION 2: REGULATORY OVERSIGHT
- SECTION 3: VOLUNTARY ACCREDITATION/MEMBERSHIP AGENCIES
- SECTION 4: OTHER SAFETY REGULATIONS
- SECTION 5: QUALITY MANAGEMENT ACTIVITIES
- SECTION 6: RESOURCES
- SECTION 7: EQUIPMENT management
- SECTION 8: SUPPLIERS AND MATERIALS management
- SECTION 9: PROCESS CONTROL AND MANAGEMENT
- SECTION 10: DOCUMENTS AND RECORDS
- SECTION 11: NONCONFORMING EVENT IDENTIFICATION, INVESTIGATION, AND RESOLUTION
- SECTION 12: ASSESSMENTS: INTERNAL AND EXTERNAL
- SECTION 13: PROCESS IMPROVEMENT
- SECTION 14: Facilities, Work Environment, and Safety
- CHAPTER SUMMARY
- CRITICAL THINKING EXERCISES
- STUDY QUESTIONS
- REFERENCES
- Part II: Foundations: Basic Sciences and Reagents
- 2. Immunology: Basic Principles and Applications in the Blood Bank
- CHAPTER OUTLINE
- KEY TERMS
- SECTION 1: CHARACTERISTICS ASSOCIATED WITH ANTIGEN-ANTIBODY REACTIONS
- SECTION 2: CHARACTERISTICS ASSOCIATED WITH RED CELL ANTIGEN-ANTIBODY REACTIONS
- Factors Influencing Sensitization Stage
- Factors Influencing Lattice Formation
- SECTION 3: APPLICATION OF RED CELL ANTIGEN-ANTIBODY REACTIONS FOR ROUTINE TESTING IN IMMUNOHEMATOLOGY
- REFERENCES
- 3. Blood Banking Reagents: Overview and Applications
- CHAPTER OUTLINE
- KEY TERMS
- SECTION 1: INTRODUCTION TO BLOOD BANKING REAGENTS
- SECTION 2: COMMERCIAL ANTIBODY REAGENTS
- SECTION 3: REAGENT RED CELLS
- SECTION 4: THE ANTIGLOBULIN TEST AND REAGENTS
- SECTION 5: ANTIBODY POTENTIATORS AND LECTINS
- REFERENCES
- 4. Blood Banking Genetics
- CHAPTER OUTLINE
- KEY TERMS
- SECTION 1: BLOOD GROUP SYSTEM GENETICS
- SECTION 2: POPULATION GENETICS
- SECTION 3: MOLECULAR GENETIC TECHNIQUES
- REFERENCES
- Part III: Overview of the Major Blood Groups
- 5. ABO and H Blood Group Systems and Secretor Status
- CHAPTER OUTLINE
- KEY TERMS
- SECTION 1: HISTORICAL OVERVIEW OF ABO BLOOD GROUP SYSTEM
- SECTION 2: ABO AND H BLOOD GROUP SYSTEM ANTIGENS
- SECTION 3: GENETIC FEATURES OF ABO BLOOD GROUP SYSTEM
- SECTION 4: ABO BLOOD GROUP SYSTEM ANTIBODIES
- SECTION 5: ABO BLOOD GROUP SYSTEM AND TRANSFUSION
- SECTION 6: RECOGNITION AND RESOLUTION OF ABO DISCREPANCIES
- SECTION 7: SPECIAL TOPICS RELATED TO ABO AND H BLOOD GROUP SYSTEMS
- REFERENCES
- 6. Rh Blood Group System
- Chapter Outline
- KEY TERMS
- SECTION 1 DISCOVERY OF THE D ANTIGEN
- SECTION 2 GENETICS, BIOCHEMISTRY, AND TERMINOLOGY
- SECTION 3 ANTIGENS OF THE Rh BLOOD GROUP SYSTEM
- SECTION 4 Rh ANTIBODIES
- SECTION 5 LW (LANDSTEINER-WIENER) BLOOD GROUP SYSTEM
- References
- 7. Other Red Cell Blood Group Systems, Human Leukocyte Antigens, and Human Platelet Antigens
- Chapter Outline
- KEY TERMS
- SECTION 1 WHY STUDY OTHER BLOOD GROUP SYSTEMS?
- SECTION 2 KELL BLOOD GROUP SYSTEM
- SECTION 3 Kx BLOOD GROUP SYSTEM
- SECTION 4 DUFFY BLOOD GROUP SYSTEM
- SECTION 5 KIDD BLOOD GROUP SYSTEM
- SECTION 6 LUTHERAN BLOOD GROUP SYSTEM
- SECTION 7 LEWIS BLOOD GROUP SYSTEM
- SECTION 8 I BLOOD GROUP SYSTEM AND Ii BLOOD GROUP COLLECTION
- SECTION 9 THE P1PK AND GLOBOSIDE BLOOD GROUP SYSTEMS
- SECTION 10 MNS BLOOD GROUP SYSTEM
- SECTION 11 MISCELLANEOUS BLOOD GROUP SYSTEMS
- SECTION 12 HUMAN LEUKOCYTE ANTIGEN SYSTEM AND PLATELET ANTIGENS
- References
- Part IV: Essentials of Pretransfusion Testing
- 8. Antibody Detection and Identification
- Outline
- KEY TERMS
- SECTION 1 ANTIBODY DETECTION
- SECTION 2 ANTIBODY IDENTIFICATION
- ANTIBODIES FORMERLY KNOWN AS HIGH-TITER, LOW-AVIDITY ANTIBODIES
- SECTION 3 AUTOANTIBODIES AND AUTOIMMUNE HEMOLYTIC ANEMIA
- References
- 9. Compatibility Testing
- Chapter Outline
- KEY TERMS
- SECTION 1 PRINCIPLES OF THE CROSSMATCH
- SECTION 2 PRINCIPLES OF COMPATIBILITY TESTING
- SECTION 3 COMPATIBILITY TESTING SPECIAL TOPICS
- References
- 10. Blood Bank Automation for Transfusion Services
- Chapter Outline
- KEY TERMS
- SECTION 1 INTRODUCTION TO AUTOMATION IN the TRANSFUSION SERVICE LABORATORY
- SECTION 2 MEETING THE LABORATORY’S AUTOMATION NEEDS
- SECTION 3 AUTOMATED TESTING TECHNOLOGY AND SYSTEMS
- References
- Part V: Clinical Considerations in Immunohematology
- 11. Transfusion Reactions and Other Adverse Events
- Chapter Outline
- KEY TERMS
- SECTION 1 OVERVIEW OF ADVERSE REACTIONS TO TRANSFUSION
- SECTION 2 CATEGORIES OF TRANSFUSION REACTIONS
- SECTION 3 EVALUATION AND REPORTING OF A TRANSFUSION REACTION
- References
- 12. Hemolytic Disease of the Fetus and Newborn
- Chapter Outline
- KEY TERMS
- SECTION 1 WHAT IS HEMOLYTIC DISEASE OF THE FETUS AND NEWBORN?
- SECTION 2 DIAGNOSIS OF AND MANAGEMENT OF HDFN
- SECTION 3 POSTPARTUM TESTING OF NEWBORNS
- D Antigen Testing
- ABO Antigen Testing
- Direct Antiglobulin Test
- SECTION 4 TREATMENT OF HDFN
- SECTION 5 PREVENTION OF HDFN
- References
- Part VI: Blood Collecting and Testing
- 13. Donor Selection and Phlebotomy
- Chapter Outline
- KEY TERMS
- SECTION 1 DONOR SCREENING AND QUALIFICATION
- SECTION 2 PHLEBOTOMY
- SECTION 3 SPECIAL BLOOD COLLECTION
- References
- 14. Testing of Donor Blood
- Chapter Outline
- KEY TERMS
- SECTION 1 OVERVIEW OF DONOR BLOOD TESTING
- SECTION 2 SEROLOGIC TESTING OF DONOR UNITS
- SECTION 3 INFECTIOUS DISEASE ASSAYS
- SECTION 4 IDENTIFYING RISKS
- References
- Part VII: Blood Component Preparation and Transfusion Therapy
- 15. Blood Component Preparation and Therapy
- Chapter Outline
- KEY TERMS
- SECTION 1 BLOOD COLLECTION AND STORAGE
- SECTION 2 BLOOD COMPONENT PREPARATION
- SECTION 3 DISTRIBUTION AND ADMINISTRATION
- References
- 16. Transfusion Therapy in Selected Patients
- Chapter Outline
- KEY TERMS
- SECTION 1 TRANSFUSION PRACTICES
- SECTION 2 TRANSPLANTATION AND CELLULAR THERAPIES
- SECTION 3 THERAPEUTIC APHERESIS
- SECTION 4 HEMOSTASIS AND HEMOSTATIC DISORDERS
- References
- Answers to Study Questions
- Chapter 1
- Chapter 2
- Chapter 3
- Chapter 4
- Chapter 5
- Chapter 6
- Chapter 7
- Chapter 8
- Chapter 9
- Chapter 10
- Chapter 11
- Chapter 12
- Chapter 13
- Chapter 14
- Chapter 15
- Chapter 16
- Glossary
- Index
- No. of pages: 416
- Language: English
- Edition: 6
- Published: November 12, 2024
- Imprint: Elsevier
- Paperback ISBN: 9780443113659
- eBook ISBN: 9780443118586
PH
Paula R. Howard
Paula Howard worked at Johnson & Johnson as the Principal Scientist in Ortho Clinical Diagnostics for seven years, at OneBlood, Inc. as the GxP Training Manager for 2 years and Director of Regulated and Business Application Training for 3 years. She has certificates in eLearning instructional design and is currently working as a career coach.
Affiliations and expertise
OneBlood, Inc., Lauderhill, Florida, USAWH
Wyenona Hicks
Wyenona “Nonie” Hicks, MS, MT(ASCP)SBB attended the Medical Technology program at the University of Louisville in Kentucky, where she earned her MT(ASCP) certification. She later earned a Master of Science degree in Transfusion and Transplantation Science at the University of Cincinnati’s Hoxworth Blood Center in Ohio, as well as her ASCP(SBB) certification. Of her 38 years of working experience, “Nonie” has spent almost half of that time doing what she loves best, teaching. Her roles as an educator include the following: 1) Manager of Medical Technology Education at OneBlood, Inc. where she taught Blood Bank Technology (BBT), MLS, and SBB students (distance learning); 2) Adjunct and full-time MLS Instructor at the University of Central Florida; 3) Full-time assistant professor in the Clinical Laboratory Science BS and MS programs at the University of Tennessee Health Science Center, Memphis TN; 4) Adjunct instructor for Rush University’s distance learning SBB program; and 5) Adjunct instructor for University of Cincinnati’s Medical Laboratory Science Online AS to BS Program. She has published articles and delivered lectures at local, state, national, and international meetings.
Affiliations and expertise
Educator/Author, Ocala, Florida, USA