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Aulton's Pharmaceutics

The Design and Manufacture of Medicines

  • 5th Edition - June 16, 2017
  • Latest edition
  • Editors: Kevin M.G. Taylor, Michael E. Aulton
  • Language: English

This is the best known text on pharmaceutics. Its strength lies mainly in being a complete course in one book. Reviewers consistently praise its comprehensiveness and its ex… Read more

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Description

This is the best known text on pharmaceutics. Its strength lies mainly in being a complete course in one book. Reviewers consistently praise its comprehensiveness and its extremely high quality-quality content. Pharmaceutics is one of the most diverse subject areas in pharmaceutical science and an understanding of it is vital for all pharmacists and scientists involved in converting drugs to medicines that can be safely delivered to a patient. The editorial and author team deliver a tour de force of accessibility, coverage and currency in this new edition of a world-class textbook.

Key features

  • Relevant chemistry covered throughout
  • Reflects current and future use of biotechnology products throughout
  • Covers ongoing changes in our understanding of biopharmaceutics, certain areas of drug delivery and the significance of the solid state
  • Includes the science of formulation and drug delivery
  • Designed and written for newcomers to the design of dosage forms
  • Key points boxes throughout
  • Summaries at the end of each chapter

Readership

Pharmacy and pharmaceutical science students; Pharmacology students; Biomedicine students; Practitioners in the pharmaceutical industry

Table of contents

What is pharmaceutics?


1. Design of dosage forms

PART 1 Scientific principles of dosage form design

2. Dissolution and solubility

3. Properties of solutions

4. Surfaces and interfaces

5. Disperse systems

6. Rheology

7. Kinetics

PART 2 Particle science and powder technology

8. Solid-state properties

9. Particle size analysis

10. Particle size reduction and size separation

11. Mixing

12. Powder flow

PART 3 Pharmaceutical microbiology and serialization

13. Fundamentals of microbiology

14. Pharmaceutical applications of microbiological techniques

15. Action of physical and chemical agents on microorganisms

16. Principles of sterilization

17. Sterilization in practice

PART 4 Biopharmaceutical principles of drug delivery

18. Introduction to biopharmaceutics

19. Gastrointestinal tract – physiology and drug absorption

20. Bioavailability – physicochemical and dosage form factors

21. Assessment of biopharmaceutical properties

22. Dosage regimens

PART 5 Dosage form design and manufacture

23. Pharmaceutical preformulation

24. Solutions

25. Clarification

26. Suspensions

27. Emulsions and creams

28. Powders, granules and granulation

29. Drying

30. Tablets and compaction

31. Modified-release oral drug delivery

32. Coating of tablets and multiparticulates

33. Hard capsules

34. Soft capsules

35. Dissolution testing of solid dosage forms

36. Parenteral drug delivery

37. Pulmonary drug delivery

38. Nasal drug delivery

39. Ophthalmic drug delivery

40. Topical and transdermal drug delivery

41. Rectal and vaginal drug delivery

42. The formulation and manufacture of plant medicines

43. Delivery of biopharmaceuticals

44. Pharmaceutical nanotechnology and nanomedicines

45. Design and administration of medicines for children and the elderly

PART 6 Packaging and stability of pharmaceutical products

46. Packaging

47. Chemical stability in dosage forms

48. Microbial contamination, spoilage and preservation of medicines

49. Product stability and stability testing

Online self assessment

Review quotes

'I have a BSc Chemistry MSc Medicinal Chemistry and now I study B.Pharm Pharmacy. I bought this book for my class in Pharmaceutical Technology and, with a strong background in Physical Chemistry, I found this book very good for the transition from Physical Chemistry to Physical Pharmacy. It is ideal both for study and reference.'

'I have tried all these books, even 2007 version of it, I hated Aulton 2007 but this book is amazing!It has been neatly tidied up and with sections and very good summary in the beginning it has covered almost everything (looking forward for more in the future!).'

'...easy to read ... The table of contents at the beginning of the each chapter is really good, the diagrams have been renewed. The language of the book has also changed and the explanations were further simplified so that we actually understand the concept even better!'

'I bought this textbook because it was the recommended textbook for our pharmaceutics lectures. I would always recommend this textbook.'

From a review of the previous edition:
‘For all the pharmacy students out there part of your pharmacy degree will be to study formulation design and pharmaceutics. This is the holy grail of pharmaceutical technology books. The text reads well and introduces difficult concepts in a more easy-to-understand way, it is definitely worth the money to help you get through the module, if you’re doing a research project in pharmaceutical design then this would also be an excellent buy…This is essential for passing exams and developing professional competence.’

Product details

  • Edition: 5
  • Latest edition
  • Published: July 7, 2017
  • Language: English

About the editors

KT

Kevin M.G. Taylor

Affiliations and expertise
Professor of Clinical Pharmaceutics, UCL School of Pharmacy, London, UK

MA

Michael E. Aulton

Affiliations and expertise
Emeritus Professor, De Montfort University, Leicester, UK