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Elsevier

Atopic Dermatitis: Inside Out or Outside In

  • 1st Edition -
  • Latest edition
  • Editors: Lawrence S Chan, Vivian Y. Shi
  • Language: English

Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etio… Read more

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Description

Atopic dermatitis (eczema) is one of the most common and most challenging skin conditions, for patients and practitioners alike. Uniquely organized by intrinsic and extrinsic etiologies, Atopic Dermatitis: Inside Out or Outside In? examines a myriad of causes that start from both the inside of the body and from the external environment, offering physicians practical ways to design treatments that specifically address these causes. Drs. Lawrence S. Chan and Vivian Y. Shi, along with a team of expert contributing authors, examine the etiology of this complex disorder and provide targeted, comprehensive solutions and the most useful therapeutic plans based on pathophysiology, including evidence-based integrative management.

Key features

  • Analyzes the pathophysiology of atopic dermatitis from two distinct fronts: inside out and outside in—an approach that is unique in the field.

  • Begins with an overview of the disease, then delves into both internal and external pathogenic factors, followed by the Clinician’s Corner, which offers practical recommendations for treatment.

  • Organizes therapeutic discussions by corresponding pathophysiology rather than a one-size-fits-all approach.

  • Covers recently FDA-approved and emerging medications, as well as atopic comorbidities.

  • Enhanced eBook version included with purchase.

    • Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Readership

Dermatologists (~11,000 in the US, out of which 1700 are residents), immunologists & allergists (4460 in the US), allergy fellows, infectious disease specialists (9000 in the US); pediatricians specializing in allergy.

Table of contents

Section I: A History of Atopy

1 Historic Perspective

2 Atopy Redefined

3 Atopy of the Skin

4 Epidemiology

Section II: External Factors

5 Skin Barrier

6 Skin and Gut Microbiome

7 Immunogens

8 Nutrition

9 Oxidative Stress, Environmental factors, Pollutants

10 Clinical Evidence: External Factors

Section III: Internal Factors

11 Keratinocytes

12 Microvasculature

13 Humoral Factors

14 Cellular Factors

15 Skin-Gut-Lung Epithelial Permeability

16 Neurosensory Mechanisms

17 Epigenetics

18 Clinical Evidence: Internal Factors

Section IV: Clinician's Corner

19 Therapeutic Guideline Overview

20 Topical Therapies

21 Wound care

22 Skin barrier Repair

23 Emerging Targeted Treatments

24 Microbiome Modulation

25 Itch and Pain Treatments

26 Complementary and Alternative Approaches 1

27 Complementary and Alternative Approaches 2

Review quotes

"The progress that has been made in treating atopic dermatitis has been exciting and life changing for patients. This book allows readers to stay updated and replace older references on the subject."

©Doody’s Review Service, 2022, Patricia Wong, MD (Private Practice) Doody's Score: 5 Stars!

Product details

  • Edition: 1
  • Latest edition
  • Published: January 14, 2022
  • Language: English

About the editors

LC

Lawrence S Chan

Affiliations and expertise
Dr. Orville J Stone Endowed Professor, Department of Dermatology, University of Illinois at Chicago, Chicago, Captain James Lovel Federal Health Care Centre, North Chicago, IL, USA

VS

Vivian Y. Shi

Dr. Vivian Shi is the Director of Clinical Trials and the Eczema Specialty Clinic at the University of Arkansas for Medical Sciences. Her research and clinical interests are in complex inflammatory skin conditions, skin barrier repair, transepidermal drug delivery, and integrative dermatology. She was an integral part of the team of researchers characterizing the pathophysiology of atopic dermatitis using a transgenic interleukin-4 mouse model of atopic dermatitis. She has published over 150 peer-reviewed articles, and is on the speaker’s bureau and the steering committee for the U.S. National Eczema Association and is a faculty member of the International Eczema Council. She has served as the principal investigator for numerous industry-sponsored and investigator-initiated clinical and translational studies in eczematous conditions. She regularly speaks in national and international conferences on atopic dermatitis and inflammatory skin conditions. Additionally, she is the recipient of the several prestigious awards and grants.
Affiliations and expertise
Associate Professor, Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA

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