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Atlas of Liver Pathology
- 4th Edition - April 7, 2023
- Author: Gary C. Kanel
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 8 2 5 3 3 - 7
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 8 2 5 3 4 - 4
Highly illustrated and conveniently templated for quick reference, Atlas of Liver Pathology, 4th Edition, is a useful Atlas and text for every practicing pathologist or trainee who… Read more
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Institutional subscription on ScienceDirect
Request a sales quoteHighly illustrated and conveniently templated for quick reference, Atlas of Liver Pathology, 4th Edition, is a useful Atlas and text for every practicing pathologist or trainee who assesses liver biopsy specimens. From cover to cover, it contains all the information needed to identify histologic features and correlate them with clinical findings, offering a clearer understanding of the clinical implications of the disease as it relates to treatment. More than 1,200 high-quality, full-color images and illustrations provide you with a complete visual guide to the vast majority of liver diseases and assist in the diagnoses of biopsy and resected liver specimens.
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Provides clear, templated information for each disease: Major Morphologic Features; Special Stains; Differential Diagnoses; Clinical and Biologic Behavior; and Treatment and Prognosis.
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Incorporates relevant data from ancillary techniques (immunohistochemistry, cytology, cytogenetics and molecular genetics), giving you the necessary tools required to master the latest breakthroughs in diagnostic technology.
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Incorporates the latest diagnostic biomarkers and their utility in differential diagnoses, newly described variants, and new histologic entities.
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Contains two new chapters on liver biopsy interpretation and autoimmune hepatitis.
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Features concise, bulleted text and abundant tables that cover common as well as rare diseases, differential diagnoses, and more.
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An eBook version is included with purchase. The eBook allows you to access all of the text, tables, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
General surgical pathologists in practice and in training (38,000).
- Cover image
- Title page
- Table of Contents
- Copyright
- Dedication
- Preface
- Part I. Liver and Hepatobiliary Pathology With Clinical Correlations
- 1. Liver: Embryology, Gross and Microscopic Anatomy, and Function
- Embryology
- Gross Anatomy
- Microanatomy
- Progenitor and Stem Cells
- 2. Liver Biopsy Evaluation With Histologic, Laboratory, and Clinical Parameters
- Liver Biopsy Techniques
- Conditions Necessitating Liver Biopsy
- Complications in Liver Biopsy Interpretation
- Common Pigments
- Nonspecific Features
- Systematic Approach in Liver Biopsy Interpretation: Morphology with Clinical and Laboratory Considerations
- General Clinical Considerations for Acute and Chronic Liver Diseases
- 3. Viral Hepatitis
- Major Hepatotropic Viruses: A, B, δ (Delta), C, E, G, “NON-A Through NON-G”
- Systemic Viral Infections with Hepatic Involvement
- Rare Systemic Viral Infections with Hepatic Involvement
- Lassa Fever
- Yellow fever
- Other Viruses that may Cause Liver Damage
- 4. Cholestasis and Biliary Tract Disorders
- Cholestasis and the Anatomy of the Biliary System
- Bilirubin Metabolism
- Extrahepatic (Mechanical) Bile Duct Obstruction
- Primary Biliary Cholangitis
- Primary Sclerosing Cholangitis
- Secondary Sclerosing Cholangitis
- IgG4-Associated Sclerosing Cholangitis
- Recurrent Pyogenic Cholangiohepatitis
- Other Cholestatic and Biliary Tract Disorders that May Cause Liver Damage
- 5. ALCOHOLIC AND NON-ALCOHOLIC FATTY LIVER DISEASES
- Perivenular Alcoholic Fibrosis
- 6. Drug and Toxin-Induced Liver Injury
- Overview of Drug- and Toxin-Induced Injury
- Hepatocellular Necrosis With Minimal To Absent Inflammation
- Hepatocellular Necrosis With Inflammation
- Lobular Confluent Necrosis With Inflammation
- Steatosis
- Ethanol
- Granulomas
- Mallory-Denk Bodies
- Cholestasis, Simple
- Cholestasis With Inflammation
- Bile Ducts: Inflammation and Injury
- Vascular Disorders
- Fibrosis
- Neoplasms And Related Lesions
- Miscellaneous Drug and Toxin-Induced Lesions
- 7. Vascular Disorders
- Introduction to Vascular Diseases of the Liver
- Pathology Involving the Hepatic Vein and Hepatic Venous Outflow Vessels
- Acute
- Chronic
- Major morphologic features
- Chronic
- Pathology Involving the Portal Vein and Intrahepatic Branches
- Pathology Involving the Hepatic Artery and Intrahepatic Branches
- Clinical and biologic behavior
- Churg-Strauss syndrome
- Pathology Involving the Hepatic Sinusoids
- Major morphologic features
- Chronic
- Miscellaneous Vascular Conditions
- Other Causes of Vascular Disorders that May Involve the Liver
- 8. Infectious Diseases, Non-viral
- 9. Autoimmune Hepatitis
- Introduction to Autoimmune Hepatitis
- Autoimmune Hepatitis
- Autoimmune Hepatitis Overlap Syndromes
- 10. Developmental, Familial, and Metabolic Disorders
- Introduction to Developmental, Familial, and Metabolic Diseases
- Neonatal Hepatitis
- Biliary Atresia
- Cystic Diseases of the Liver
- Caroli disease
- Biliary microhamartoma (von Meyenburg complex)
- Peribiliary hilar cysts
- Polycystic Disease
- Congenital hepatic fibrosis (juvenile/adult type)
- Adult polycystic liver disease (PCLD) without renal involvement
- Cystic Fibrosis (Mucoviscidosis)
- Disorders of Endoplasmic Reticulum
- Hereditary Hyperbilirubinemias
- Gilbert syndrome
- Dubin-Johnson syndrome
- Progressive familial intrahepatic cholestasis (PFIC type 1) (Byler syndrome)
- Progressive familial intrahepatic cholestasis (PFIC type 1 variant) (benign recurrent intrahepatic cholestasis [BRIC] type 1)
- Disorders of Amino Acid Metabolism
- Storage Disorders
- Mitochondrial Fatty Acid Oxidation Disorders
- Porphyrias
- Sickle Cell Anemia
- Other Developmental, Familial, and Metabolic Disorders That May Cause Liver Damage
- 11. Diseases of Hepatic Iron and Copper Metabolism
- Iron Storage Disorders
- Grading of stainable hepatic iron
- Hepatic iron quantitation (hepatic iron index [HII])
- Copper Storage Disorders
- Cirrhotic stage
- 12. Neoplasms and Related Lesions
- Primary Benign Hepatic Neoplasms
- Mucinous cystic neoplasm
- Angiomyolipoma
- Mesenchymal hamartoma
- Lymphangioma
- Solitary fibrous tumor
- Teratoma
- Plexiform neurofibroma (nerve sheath tumor)
- Biliary papillomatosis
- Primary Malignant Hepatic Neoplasms
- Hepatocellular carcinoma
- Cholangiocarcinoma
- Cholangiocarcinoma
- Combined hepatocellular–cholangiocarcinoma
- Rare mesenchymal malignant tumors
- Yolk sac tumor
- Cystic mesothelioma, malignant variant
- Hematologic Diseases
- α-heavy chain disease
- Metastatic Neoplasms
- Tumor-Like Lesions
- Regenerative Cirrhotic Nodules
- 13. Transplantation
- Introduction to Liver Transplant Pathology
- Back-Table Assessment of Donor Liver and Immediate Postperfusion State
- Time Frame of Liver Allograft Pathology
- Preservation (Harvesting, Reperfusion) Injury
- Acute Graft Failure (Primary Graft Nonfunction)
- Rejection
- Posttransplant Complications
- Posttransplant Opportunistic Infections
- Posttransplant Lymphoproliferative Disorder (PTLD) (Ebv Related and Non–Ebv Related)
- Recurrent Disease
- Acquired (De Novo) Posttransplant Liver Diseases
- Hepatic Changes After Hematopoietic Stem Cell Transplant: Graft-Versus-Host Disease (GVHD)
- 14. Miscellaneous Systemic Diseases With Hepatic Involvement
- Granulomatous Liver Diseases
- Liver In Inflammatory Bowel Disease
- Amyloidosis
- Conditions Seen In Pregnancy
- Hyperalimentation (Total Parenteral Nutrition [TPN])
- Adults
- Hemophagocytic Syndromes
- Hyperpyrexia and Heat Stroke
- Reye Syndrome
- Other Miscellaneous Conditions Associated With Liver Diseases
- Part II. Liver Biopsy Evaluation: Morphology With Differential Diagnoses
- PART II. LIVER BIOPSY EVALUATION: MORPHOLOGY WITH DIFFERENTIAL DIAGNOSES
- Introduction
- Tables of Morphology
- Index
- No. of pages: 624
- Language: English
- Edition: 4
- Published: April 7, 2023
- Imprint: Elsevier
- Hardback ISBN: 9780323825337
- eBook ISBN: 9780323825344
GK
Gary C. Kanel
Dr. Kanel has been a faculty member at the USC School of Medicine since 1979, with interests centering on liver pathology and pathophysiologic concepts. He has co-authored over ninety peer review journal articles, has written over 40 book chapters and monographs, and has given over 120 lectures and workshops, virtually all related to liver pathology. He also is involved in research involving various liver disorders, in particular fatty liver diseases and tumors.
Affiliations and expertise
Professor of Clinical Pathology, University of Southern California, Associate Pathologist, Los Angeles County & USC Medical Center and USC University Hospital, Los Angeles, CA