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Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging

1st Edition - May 4, 2017
Authors: Lambros S Athanasiou, Dimitrios I Fotiadis, Lampros K Michalis
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 0 4 7 3 4 - 7
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 0 5 1 1 3 - 9

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and character… Read more

Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging

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Atherosclerotic Plaque Characterization Methods Based on Coronary Imaging provides a complete review of computer methods for atherosclerotic plaque reconstruction and characterization. The authors, with their expertise from biomedical engineering, computer science, and cardiology, offer a holistic view. The focus of the book is on the presentation of major imaging techniques, including their limitations. It includes details on the mechanical characterization and properties of plaques and appropriate constitutive models to describe the mechanical behavior of plaques.

The authors explore the challenges of using multiple coronary imaging technologies, and provide the pros and cons of invasive vs. non-invasive techniques. Methods for plaque characterization and 3D reconstruction of coronary arteries using IVUS, OCT, and CT images are described.

This book will help readers study new trends in image processing analysis and plaque characterization, implement automated plaque characterization methodologies, understand coronary imaging drawbacks, and comprehend 3 dimensional coronary artery and plaque reconstruction methods.

Chapter 1: Introduction

1.1 Anatomy and Physiology of the Cardiovascular System

1.2 Atherosclerosis

1.3 Imaging of Atherosclerosis: Invasive and Non-invasive Techniques

Chapter 2: Principles of Coronary Imaging Techniques

2.1 Coronary Angiography

2.2 Intravascular ultrasound - IVUS

2.3 Optical coherence tomography - OCT

2.4 Computed Tomography - CT

Chapter 3: Quantitative Coronary Angiography methods

3.1 Two Dimensional (2D) Coronary Quantitative Angiography

3.2 Three Dimensional (3D) Coronary Angiography

3.3　Functionality of 　Three Dimensional (3D) 　Reconstruction: Fractional　Flow Reserve Calculation (FFR)

Chapter 4: Plaque Characterization Methods using Intravascular Ultrasound Imaging (IVUS)

4.1 Plaque Segmentation

4.2 Plaque Characterization

Chapter 5: Plaque Characterization Methods using Optical Coherence Tomography (OCT)

5.1 Plaque Segmentation Methods using OCT

5.2 Plaque Characterization 　using OCT

5.3 Plaque Characterization

5.4　Plaque characterization and plaque phenotype

Chapter 6: Plaque Characterization Methods using Computed Tomography (CT)

6.1 Lumen detection methods

6.2 Plaque detection methods

6.3 CTA segmentation

6.4 3D Artery and 3D CP reconstruction

6.5 Can CTA plaque characterization accuracy be affected?

Chapter 7: Methods for Three Dimensional (3D) reconstruction of Coronary Arteries and　Plaque

7.1　Methods 　for 　Three 　Dimensional 　(3D) 　reconstruction 　of 　Coronary　Arteries based on a single intravascular imaging modality

7.2 　Methods 　for 　Three 　Dimensional 　(3D) 　reconstruction 　of 　Coronary　Arteries based on the fusion of intravascular imaging modalities

7.3 Intravascular 3D reconstruction tools

Chapter 8: Propagation of Segmentation and Imaging System Errors

8.1 Imaging Systems and Segmentation Errors

8.2 Fundamental statistics for propagating the error

8.3 Error propagation in plaque characterization

Chapter 9: Validation using Histological and Micro-CT Data: Registration and Inflation using IVUS

9.1 Micro-CT　vs　Histology

9.2 Image Registration Methods in Medical Imaging

9.3 Inflating Deformed Vessel Images

Chapter 10: Structure and Mechanical Behavior of Atherosclerotic Plaque

10.1 Mechanical Plaque Characterization

10.2 Plaque Development Models

10.3　Prognosis of Atherosclerosis

Chapter 11: Conclusions and Future Trends

11.1 Towards novel imaging modalities

11.2 Hybrid Imaging

LA

Lambros S Athanasiou

Lambros S. Athanasiou received his diploma degree from the Department of Information and Communication Systems Engineering, University of the Aegean, Greece, in 2009 and the PhD degree from the Department of Materials Science and Engineering, University of Ioannina, Greece, in 2015. He is currently working as a Postdoctoral Research Fellow at the Institute for Medical Engineering & Science, Massachusetts Institute of Technology, Cambridge, MA, USA. His research interests include medical image processing, biomedical engineering, decision support and medical expert systems.

Affiliations and expertise

Information and Communication Systems Engineer, Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA

DF

Dimitrios I Fotiadis

Dimitrios I. Fotiadis received his Diploma degree in chemical engineering from National Technical University of Athens, Athens, Greece, in 1985 and the Ph.D. degree in chemical engineering from the University of Minnesota, Minneapolis, MN, in 1990. He is currently Professor at the Department of Materials Science and Engineering, University of Ioannina, Greece, and affiliated researcher at the Biomedical Research Dept. of the Institute of Molecular Biology and Biotechnology - FORTH. He is the Director of the Unit of Medical Technology and Intelligent Information Systems, Greece. He is the member of the board of Michailideion Cardiology Center. His research interests include modeling of human tissues and organs, intelligent wearable devices for automated diagnosis and processing/analysis of biomedical data.

Affiliations and expertise

Professor of Biomedical Engineering, Department of Materials Science and Engineering, University of Ioannina, Greece

LM

Lampros K Michalis

Lampros K. Michalis received his M.D. degree with Distinction from the University of Athens Medical School, Greece in 1984 and in 1989, he was awarded his M.D. Thesis with Distinction also from the University of Athens Medical School. He has been fully trained in clinical and interventional cardiology in the United Kingdom. Since 1995 he has been with the University of Ioannina Medical School, Ioannina, Greece, where he is a Professor of Cardiology. He is the chairman of the board of Michailideion Cardiology Center. His research interests focus on interventional cardiology, vibrational angioplasty, intravascular imaging, coronary and peripheral artery disease, and bioengineering.

Affiliations and expertise

Professor of Cardiology, School of Medicine, University of Ioannina, Greece