Applications of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry
- 2nd Edition - January 1, 1969
- Latest edition
- Authors: L. M. Jackman, S. Sternhell
- Editors: D. H. R. Barton, W. Doering
- Language: English
Application of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry, Second Edition covers the theoretical background necessary for the intelligent application of NMR… Read more
Application of Nuclear Magnetic Resonance Spectroscopy in Organic Chemistry, Second Edition covers the theoretical background necessary for the intelligent application of NMR spectroscopy to common problems encountered in organic chemistry. This book is composed of five parts, and begins with introduction to the theory and practice of nuclear magnetic resonance. The succeeding chapter deals with the theory of chemical effects in NMR spectroscopy. These topics are followed by a discussion on the application of chemical shift to organic compound analysis and the principles of the spin-spin coupling .The final chapter considers the applications of time- dependent phenomena in NMR spectroscopy. This book will prove useful to analytical chemists and researchers in the allied fields.
Preface
Preface to the 1st Edition
Editorial Preface to the 2nd Edition
Part 1 an Introduction to the Theory and Practice of Nuclear Magnetic Resonance Spectroscopy
Chapter 1-1. Theory of Nuclear Magnetic Resonance
A. Dynamic and Magnetic Properties of Atomic Nuclei
B. Nuclear Resonance
C. Relaxation Processes
D. Chemical Effects in N.M.R.
Chapter 1-2. The Experimental Method
A. The Nuclear Magnetic Resonance Spectrometer
B. Experimental Factors which Influence Resolution and the Shapes of Absorption Lines
C. Experimental Factors which Influence Sensitivity (Signal-To-Noise Ratio)
D. Measurement of Line Positions and Determination of the Chemical Shift
E. Measurement of Intensities
F. Solvents
G. Deuterium Exchange
Part 2 Theory of Chemical Effects in Nuclear Magnetic Resonance Spectroscopy
Chapter 2-1. Time-Dependent Effects in Nuclear Magnetic Resonance Spectroscopy
Chapter 2-2. Theory of the Chemical Shift
A. Classification of Shielding Effects
B. Local Diamagnetic Proton Shielding
C. Long Range Shielding
D. Contact Shifts
E. The Hydrogen Bond
F. Solvent Effects
Chapter 2-3. Theory of Spin-Spin Multiplicity
A. Recognition of Spin-Spin Multiplets
B. The Mechanism of Spin-Spin Coupling
C. Analysis of N.M.R. Spectra
Chapter 2-4. Theory and Applications of Multiple Irradiation
A. Theory
B. Applications
Part 3 Applications of the Chemical Shift
Chapter 3-1. General Considerations
Chapter 3-2. Protons Bonded to Non-Cyclic Sp3 Carbon Atoms
A. H—C—C
B. H—C—X
C. Effect of Multiple Substitution At the α-Carbon Atom
Chapter 3-3. Protons Bonded to Non-Aromatic Sp2 Carbon Atoms
A. Olefinic Protons H—C=C
B. Formyl Protons H—C=X
Chapter 3-4. Protons Bonded to Sp Carbon Atoms
Chapter 3-5. Protons Bonded to Sp3 Carbon Atoms in Non-Aromatic Cyclic Structures
Chapter 3-6. Protons Bonded to Aromatic and Heterocyclic Carbon Atoms
A. Benzene Derivatives
B. Polynuclear and non-Benzenoid Carbocyclic Aromatic Compounds
C. Heterocyclic Compounds
Chapter 3-7. Protons Bonded to Elements other than Carbon
A. —OH, —NH and —SH Groups
Chapter 3-8. Stereochemistry And The Chemical Shift
A. Symmetry Arguments
B. Geometrical Isomerism in Ethylene Derivatives
C. Geometrical Isomerism in Systems Containing C=N and N = N Bonds
D. Cyclopropanes and Heterocyclopropanes
E. Multi-Ring Structures
F. Cis-Trans Stereochemistry in Four-, Five-, and Six-Membered Rings
G. The Chemical Shifts of Axial and Equatorial Protons and Groups Attached to Six-Membered Rings in Chair Conformation
H. Chemical Shift—Stereochemistry Correlations in some Complex Natural Products
I. Conformation
J. Stereochemistry and the Solvent Shift
Chapter 3-9. Carbonium Ions, Carbanions and Related Systems
A. Carbonium Ions
B. Carbanions
Part 4 Spin-Spin Coupling
Chapter 4-1. Geminal Interproton Coupling
A. Geminal Coupling Across an Sp2 Carbon Atom
B. Geminal Coupling Across an Sp2 Carbon Atom
C. Geminal Coupling Across a Heteroatom
Chapter 4-2. Vicinal Interproton Coupling
A. Vicinal Coupling Across Three Single Bonds
B. Vicinal Interproton Coupling Across One Double and Two Single Bonds
Chapter 4-3. Interproton Coupling in Aromatic and Heterocyclic Systems
A. Influence of Ring Size
B. Influence of Bond Order
C. Effects due to Heteroatoms
D. Effects due to Substituents
Chapter 4-4. Long-Range Interproton Coupling
A. Observation of Long-Range Coupling
B. Theory of Long-Range Coupling
C. Allylic and Homoallylic Coupling
D. Long-Range Coupling in Acetylenes, Allenes and Cumulenes
E. Benzylic Coupling
F. Coupling between Protons Separated by Five Bonds Along an Extended Zig-Zag Path
G. Coupling Across Four Single Bonds
H. Long-Range Coupling in 1,3-Butadiene Derivatives
I. Miscellaneous Examples of Long-Range Coupling
Chapter 4-5. Coupling between Protons and other Nuclei
A. Coupling between 1H and 13C
B. Coupling between 1H and 19F
C. Coupling between 1H and 31P
D. Coupling between Protons and Other Elements
Part 5 Applications of Time-Dependent Phenomena
Chapter 5-1. General Applications
A. Experimental Methods Involved in the Study of Time-Dependent Phenomena in N.M.R. Spectroscopy
B. Hydrogen Exchange and Hydrogen Bonding
C. Ligand Exchange
D. Partial Double Bond Character
E. Valence-Bond Tautomerism
F. Conformational Changes
G. Miscellaneous Processes
Chapter 5-2. Internal Rotation and Equivalence of Nuclei
Chapter 5-3. Tautomerism
References
Index
Other Titles in the Series
- Edition: 2
- Latest edition
- Published: January 1, 1969
- Language: English
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