Analytical Methods for Organic Cyano Groups
- 1st Edition - November 13, 2013
- Author: M. R. F. Ashworth
- Editors: R. Belcher, D. M. W. Anderson
- Language: English
- Hardback ISBN:9 7 8 - 0 - 0 8 - 0 1 6 1 9 1 - 4
- Paperback ISBN:9 7 8 - 1 - 4 8 3 2 - 3 3 6 8 - 0
- eBook ISBN:9 7 8 - 1 - 4 8 3 2 - 7 8 6 1 - 2
Monographs in Organic Functional Group Analysis, Volume 6: Analytical Methods for Organic Cyano Groups describes both qualitative and quantitative analytical methods for analysis… Read more
Monographs in Organic Functional Group Analysis, Volume 6: Analytical Methods for Organic Cyano Groups describes both qualitative and quantitative analytical methods for analysis of various organic cyano groups. This book is organized into two parts encompassing 12 chapters. Part A presents some chemical methods, which are classified according to the reaction undergone by the compound being detected, identified or determined. This part specifically covers reactions of addition to the cyano group; of other groups activated and unaffected by the cyano group; degradation reactions; and other chemical reactions. Part B highlights pure physical methods, including polarographic procedures, spectroscopic, spectrophotometric, chromatographic, and ion exchange methods, as well as azeotropic distillation. This book will be of value to organic and analytical chemists, as well as to and organic and analytical chemistry teachers, students, and researchers.
Preface
Chapter 1. Introduction
References
Part A. Chemical methods
General Introduction
Chapter 2. Reactions of (Addition to) the Cyano Group
Introduction
1. Reduction: —CN—CH2—NH2
2. Hydrolysis
3. Addition of Hydrogen Sulphide
4. Addition of Alcohols
5. Addition of Ammonia
6. Addition of Hydroxylamine
7. Addition of Hydrazine
8. Addition of Mercaptans
9. Addition of Polyphenols
10. Addition of Grignard Reagent
11. Preparation of N-(2-Chloroalkyl) amides
12. Formation of Metal Complexes
References
Chapter 3. Reactions of Groups Activated by the Cyano Group
Introduction
1. a,β-Unsaturated Nitriles
2. Compounds Containing the —CH2CN or =CHCN Group
3. Compounds Containing the -NH- or NH2 Group Attached to -CN
References
Chapter 4. Reactions of Groups Sensibly Unaffected by the Cyano Group
1. Higher Aliphatic Nitriles
2. β,y-Unsaturated Nitriles
3. Aromatic Groups in Nitriles
4. Halogen Atoms in Trichloroacetonitrile
5. Azo Group in Azobisisobutyronitrile
6. Hydrazo Group in 2,2'-Hydrazobisisobutyronitrile
7. Ester Group in Nitriles
8. Amino Groups (not Directly Linked to a Cyano Group)
9. Amidino or Guanidino Group in Dicyanodiamide
10. Cobalt in Vitamin B12 (Cyanocobalamin)
11. 5,6-Dimethylbenzimidazole in Vitamin B12
References
Chapter 5. Degradation Reactions During Which the Cyano Group Remains Intact
Introduction
1. Pyrolysis without Added Reagent
2. Pyrolysis in Presence of Oxidising Agents
3. Pyrolysis in Presence of a Base
4. Reductive Fission of TV-cyano Compounds
5. Hydrolytic Fission of Cyanohydrins
6. Formation of Bromine Cyanide, BrCN
7. Elimination of the Cyano Group in the Analytical Methods for Ethyl Dimethylphosphoramidocyanidate (Tabun)
8. Elimination of the Cyano Group as Hydrocyanic Acid in Determination of Vitamin B12
9. Formation of Thiocyanic Acid by Reaction with Sulphur
References
Chapter 6. Degradation Reactions Involving Destruction of the Cyano Group
References
Chapter 7. Miscellaneous Chemical Methods
References
Part B. Physical Methods
General Introduction
Chapter 8. Spectroscopic and Spectrophotometric Methods
1. Infrared
2. Ultraviolet and Visible
3. Mass Spectrometry
4. Flame Spectroscopy
5. Nuclear Magnetic Resonance
References
Chapter 9. Chromatographic Methods
1. Gas Chromatography
2. Other Chromatographic Methods, Principally PC and TLC
References
Chapter 10. Ion Exchange
References
Chapter 11. Polarography
References
Chapter 12. Azeotropic Distillation
References
Author Index
Subject Index
- Edition: 1
- Published: November 13, 2013
- Language: English
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