Allergy, Inflammatory, and Autoimmune Disorders in Emergency Medicine, An Issue of Emergency Medicine Clinics of North America

1st Edition, Volume 40-1 - November 19, 2021
Editors: R. Gentry Wilkerson, Sal J. Suau
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 3 5 4 6 - 6
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 3 5 4 7 - 3

This issue of Emergency Medicine Clinics, guest edited by Drs. Gentry Wilkerson, Sal J. Suau, focuses on Allergy, Inflammatory, and Autoimmune Disorders in Emergency Medicine. This… Read more

Allergy, Inflammatory, and Autoimmune Disorders in Emergency Medicine, An Issue of Emergency Medicine Clinics of North America

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This issue of Emergency Medicine Clinics, guest edited by Drs. Gentry Wilkerson, Sal J. Suau, focuses on Allergy, Inflammatory, and Autoimmune Disorders in Emergency Medicine. This issue is one of four selected each year by series Consulting Editor, Dr. Amal Mattu. Topics include: Allergy/Anaphylaxis, Anaphylaxis: Treatment in the ED, Drug Allergies, Food Allergies, Allergic acute coronary syndrome - Kounis Syndrome; Hereditary and Acquired Angioedema, Immunotherapy, Sarcoidosis, Spondyloarthritides and Autoimmune Connective Tissue Diseases.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Overview of Allergy and Anaphylaxis
Key points
Introduction
Anaphylaxis diagnosis
Definitions of persistent, refractory, and biphasic anaphylaxis
Severity grading system for acute allergic reactions
Anaphylaxis pathophysiology
Anaphylaxis epidemiology
Risk factors for severe, biphasic, and fatal anaphylaxis
Differential diagnosis
Clinics care points
Anaphylaxis: Emergency Department Treatment
Key points
Introduction
Initial evaluation and management
First-line therapy: epineprhine
Anaphylactic shock
Second-line therapy
Refractory anaphylaxis
Airway management
Observation and disposition
Future directions
Summary
Clinics care points
Disclosure
Anaphylaxis:: After the Emergency Department
Key points
Anaphylaxis: after the ED
Biphasic anaphylaxis
Protracted and refractory anaphylaxis
Prescriptions at ED discharge
Anaphylaxis management plan
Outpatient follow-up
Clinics care points
Drug Hypersensitivity Reactions
Key points
Introduction
Epidemiology
Risk factors
Classification & mechanisms
Clinical manifestations
Evaluation
Treatment
Disposition
Delabeling of drug allergies
Summary
Clinics care points
Evaluation and Management of Food Allergies in the Emergency Department
Key points
Epidemiology
Common food causes
Types of food allergies
Diagnosis of food allergies
Presentation
Management of food allergies in the emergency department
Clinics care points
Allergic Acute Coronary Syndrome—Kounis Syndrome
Key points
Introduction
Discussion
Summary
Clinics care points
Angiotensin-Converting Enzyme Inhibitor–Induced Angioedema
Key points
Introduction
Background
Epidemiology
Pathophysiology
Clinical presentation
Diagnostic evaluation
Pharmacologic treatment
Airway management
Disposition
Conclusion
Clinics care points
Hereditary Angioedema
Key points
Introduction
Epidemiology and timing of disease
Classification and pathophysiology
Clinical presentation
Diagnostic evaluation
Medical management
Airway management
Summary
Clinics care points
Mimics of Allergy and Angioedema: Scombroid, Mast Cell Activation Disorders, and Hereditary Alpha Tryptasemia
Key points
Introduction
Scombroid
Mast cell activation disorders
Hereditary alpha tryptasemia
Summary
Immune-based Therapies—What the Emergency Physician Needs to Know
Key points
Introduction
Mechanism of action
Monoclonal antibodies for autoimmune diseases
Cancer immunotherapy
Novel applications of immunotherapy in COVID-19
Other applications of immune-mediated drugs
Summary
Clinics care points
Sarcoidosis
Key points
Introduction
Epidemiology
Cause/pathogenesis
Histology
Differential diagnosis
Pulmonary sarcoidosis
Cardiac
Ocular sarcoidosis
Renal
Neurologic
Syndromes
Clinics care points
Spondyloarthritides
Key points
Introduction
Classification of spondyloarthropathies and definitions
Epidemiology
Clinical manifestations
Imaging findings
Laboratory findings
Outpatient therapies
Complications
Emergency department evaluation
Summary
Clinics care points
Autoimmune Connective Tissue Diseases: Systemic Lupus Erythematosus and Rheumatoid Arthritis
Key points
Introduction
Epidemiology
Pathophysiology
Emergency manifestations of disease
Airway-related emergencies
Cardiovascular emergencies
Gastrointestinal emergencies
Hematopoietic emergencies
Infectious disease emergencies
Neurologic emergencies
Pulmonary emergencies
Renal emergencies
Adverse drug reactions

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Allergy, Inflammatory, and Autoimmune Disorders in Emergency Medicine, An Issue of Emergency Medicine Clinics of North America

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R. Gentry Wilkerson

Sal J. Suau