Aging and the Kidney
Possible Mechanisms, Consequences, and Management Strategies
- 1st Edition - July 1, 2026
- Latest edition
- Editors: Stephen Fadem, Ahmed Arslan Yousef Awan, Emaad Abdel-Rahman
- Language: English
Aging and the Kidney: Possible Mechanisms, Consequences, and Management Strategies demonstrates the link between kidney health, well-being with increased age, and longevity. The ki… Read more
The first section delves into histological, structural, physiological, and functional changes leading to decline in kidney function with aging. The impact of nutrition and proteomics are also explained. The second section reviews function decline in elderly patients and includes subsections specific to impaired QOL, sleep quality, fall risk, frailty, depression, and sarcopenia. Unique characteristics of hypertension, diabetes, glomerulonephritis, and peripheral vascular disease are also considered. The final section is devoted to diagnostic, management, and prevention strategies. Common myths regarding chronic kidney disease in the elderly are explored, and special attention is paid to how the solitary kidney in living donors ages over time. Kidney function and its relation to neurologic complications, cancers, cardiovascular disease are presented, and current therapeutic approaches, medications, and future directions in elderly patient care are discussed. This complete work offers an invaluable resource for understanding the impact the aging kidney has on systemic health and offers potential pathways to improve lifespan and well-being in elderly patients.
- Covers histological, structural, physiological, and functional changes leading to decline in kidney function with aging
- Summarizes the most up-to-date research on the kidney’s impact on health and lifespan
- Addresses common myths regarding kidney disease in the elderly
- Provides guidance on diagnostic, management, and prevention strategies in kidney health and disease for the aging patient
1. Structure and physiological changes in the aging kidney
2. Models of aging kidney
3. Molecular mechanisms of aging in the kidney
4. The podocyte
5. Epigenetics and the kidney
6. The influence of acute kidney injury on aging
7. Nutritional considerations and aging
8. Proteomics in the kidney
PART 2 – Clinical Consequences
9. Functional impairment in elderly CKD patients
10. Unique characteristics of kidney diseases in the elderly
PART 3 – Management and Prevention
11. How to make a diagnosis of CKD in an elderly individual, since a decline in GFR is expected with normal healthy aging
12. Myths about CKD in the elderly
13. The living donor and aging
14. CNS limitations in the elderly kidney patient
15. Cancer and the kidney in an elderly individual
16. CKD and cardiovascular diseases (CVD) in an elderly individual
17. Benefits of RAAS blockage
18. Newer drugs and CKD
19. Drugs to avoid with geriatric kidney disease
20. Conservative management of ESRD
- Edition: 1
- Latest edition
- Published: July 1, 2026
- Language: English
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Stephen Fadem
Stephen Z Fadem has been in clinical practice since 1978 and is currently a Clinical Professor of Medicine at Baylor College of Medicine. During his career, he has been involved in both teaching and clinical research. Dr. Fadem’s special interests revolve around how the morbidities associated with advancing kidney disease lead to sarcopenia and frailty. He is currently in the process of planning a large fall prevention research project for dialysis patients. He has participated in 44 clinical trials and currently has 93 publications and book chapters, as well as 38 patient education articles. Dr. Fadem is the recipient of several national awards. He has been recognized as a Top Doctor by Castle-Connolly for several years, has won the Medal of Excellence from AAKP, and the Presidents Lifetime Achievement Award.
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Ahmed Arslan Yousef Awan
Dr. Ahmed Arslan Yousuf Awan is a practicing nephrologist and Assistant Professor, Department of Medicine, Nephrology and Abdominal Transplantation at the Baylor College of Medicine. Dr. Awan is founder and director of Hepatorenal services and site director for Nephrology fellowships at Baylor St. Luke’s Medical Center (BSLMC) and is the elected faculty senator for BSLMC. He is winner of Faculty of the Year award, Leadership award, Excellence in Patient Care award and has received the Houstonia top doctors award for 3 consecutive years. He is the principal investigator for an ongoing study regarding racial disparities in living kidney donation and a member of the KDIGO focused group that recently published updated guidelines regarding management of hepatitis C and CKD. He is on the faculty at Baylor College of Medicine as well as a lead in innovative national and international courses like Nephrology Business Leaders University (NBLU) and the GlomCon Fellowship.
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Emaad Abdel-Rahman
Emaad M Abdel-Rahman, MD, PhD, has been a nephrologist for over three decades specializing in caring for elderly patients with kidney disease, dialysis patients, and patients with acute and chronic kidney diseases. He is director of the UVA Kidney Center Clinic and main hemodialysis unit and leads one of the few home hemodialysis units in the country. Abdel-Rahman has been actively involved in clinical research throughout his career, including both investigator-initiated and industry-related trials. Dr Abdel-Rahman is a recipient of the UVA School of Medicine Dean’s Award for Clinical Excellence and the Department of Medicine Mentoring Excellence award. He has served on the Advisory Geriatric Nephrology Committee and as a member of the steering committee of the Kidney Health Initiative at the American Society of Nephrology. He now serves as interim director of the Nephrology Clinical Research Center within the UVA Division of Nephrology.