Advances in Virus Research
- 1st Edition, Volume 119 - June 17, 2024
- Editors: Robin MacDiarmid, Benhur Lee, Martin Beer
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 9 5 4 4 - 7
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 9 5 4 5 - 4
Advances in Virus Research, Volume 119, the latest release in this esteemed series, presents the latest research and developments in viruse… Read more
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Request a sales quoteAdvances in Virus Research, Volume 119, the latest release in this esteemed series, presents the latest research and developments in viruses.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in Advances in Virus Research series
Researchers, students, and academics in the field of virus research
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Chapter One Ubiquitination in viral entry and replication: Mechanisms and implications
- Abstract
- 1 Introduction
- 2 Ubiquitination: An overview
- 3 Ubiquitination in viral entry
- 4 Viral strategies to manipulate ubiquitination during viral replication
- 5 Antiviral effects
- 6 Therapeutic interventions by targeting ubiquitination and viral entry
- 7 Concluding remark
- Acknowledgments
- References
- Chapter Two Selection of nonstandard viral genomes during the evolution of RNA viruses: A virus survival strategy or a pesky inconvenience?
- Abstract
- 1 Introduction
- 2 What drives the selection of nsVG types and species?
- 3 Origin of nsVGs
- 4 Are nsVGs a strategy for viruses to be maintained in the host population?
- 5 Concluding remarks
- References
- Chapter Three Uncloaking the viral glycocalyx: How do viruses exploit glycoimmune checkpoints?
- Abstract
- 1 Introduction
- 2 Many viruses interact with sialic acids during entry
- 3 The sialic acid binding immunoglobulin-like lectins (Siglecs)
- 4 Viruses that engage Siglecs to dampen immune responses
- 5 Viruses that use Siglecs or Siglec-like proteins to facilitate cell entry
- 6 The glycan structures associated with virions and their roles in infection remain largely unknown, even for medically important viruses
- 7 Do viruses harness the unfolded protein response to sculpt the glycocalyxes of infected cells and virions?
- 8 Further reading
- Acknowledgments
- References
- No. of pages: 258
- Language: English
- Edition: 1
- Volume: 119
- Published: June 17, 2024
- Imprint: Academic Press
- Hardback ISBN: 9780443295447
- eBook ISBN: 9780443295454
BL
Benhur Lee
Dr. Benhur Lee is a Professor of Microbiology at the Icahn School of Medicine at Mount Sinai (ISMMS). Prof. Lee also holds the Ward-Coleman Chair in Microbiology. He obtained his M.D. from Yale University School of Medicine (1995) and completed his clinical as well as post-doctoral training at the University of Pennsylvania (1995-2001). Dr. Lee is board-certified in Clinical Pathology. Prior to 2014, he was a Professor in the Dept of Microbiology, Immunology & Molecular Genetics, and the Dept of Pathology & Laboratory Medicine at the David Geffen School of Medicine at UCLA (2001-2013).
Dr. Lee is a scientific advisor to the Standards Working Group (SWG) of the California Institute of Regenerative Medicine (CIRM, 2014-present), and was an appointed member of the NIH Director’s Recombinant DNA Advisory Committee (RAC), more recently reconstituted as the Novel and Exceptional Technology and Research Advisory Committee (NExTRAC) (2016-2022). He is an elected fellow of the American Academy of Microbiology and Councilor for Medical Virology (American Society for Virology, 2022-2025). He is also a paramyxovirus study group member of the International Committee on the Taxonomy of Viruses (ICTV) and served on the WHO R&D Blueprint pathogen prioritization scientific review group for paramyxovirus (2023-2024).
Dr. Lee has a special interest in emerging RNA viruses, with a focus on molecular viral-host interactions. His lab has made significant contributions to the study of paramyxovirus entry, budding and pathogenic mechanisms. His guiding principle is to translate insights gained from basic studies on host-pathogen interactions into anti-viral therapeutics. Dr. Lee has published over 200 peer-reviewed articles and reviews, and serves on multiple editorial boards. His work has been cited more than 15,000 times and he has a h-index of 68 as of 2024. His research has been supported by the National Institutes of Health (USA), the National Science Foundation (USA), the Department of Defense (USA) as well as private and public research foundations. Dr. Lee has trained more than a dozen post-doctoral fellows, 18 graduate students, and has served on more than 60 PhD dissertation committees between UCLA and Mount Sinai.
Affiliations and expertise
Department of Microbiology, Icahn School of Medicine at Mount Sinai, NY, USAMB
Martin Beer
Professor Martin Beer works at the Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, Germany
Affiliations and expertise
Institute of Diagnostic Virology, Friedrich-Loeffler-Institut, GermanyRead Advances in Virus Research on ScienceDirect