Advances in Structure and Activity Relationship of Coumarin Derivatives
- 1st Edition - August 7, 2015
- Editor: Santhosh Penta
- Language: English
- Paperback ISBN:9 7 8 - 0 - 1 2 - 8 0 3 7 9 7 - 3
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 3 8 7 3 - 4
Advances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceu… Read more
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Request a sales quoteAdvances in Structure and Activity Relationship of Coumarin Derivatives covers the structural behavior of various coumarin derivatives for various potential pharmaceutical applications. Based on substitution targeted for active sites, the book takes a rational approach for designing new and specific potent drugs, optimizing existing ones, and developing novel reactions. This focused primer describes the chemical structure and activity of coumarin derivatives to explore the effects of different substituents at specific positions, and their properties for effective bioactivity.
- Accessible and current coverage of coumarin derivatives from structure to potential applications
- Application of SAR technology to predict bioactivity of the derivatives based on its chemical structure
- Information for researchers in medicinal chemistry, pharmaceutical sciences, and related fields
Organic, Medicinal, Heterocycle, and Natural Products Chemists; secondarily interest in the general Pharma Sci market
- List of Contributors
- Chapter 1. Introduction to Coumarin and SAR
- 1.1 What is Coumarin?
- 1.2 Types of Coumarin and Examples
- 1.3 What is SAR?
- 1.4 Why SAR?
- 1.5 Application of SAR
- 1.6 When SAR Studies are Done
- 1.7 Needs of SAR
- 1.8 SAR of Coumarin in Disease Biology
- 1.9 Summary
- Chapter 2. Antimicrobial Agents
- 2.1 Introduction
- 2.2 What is an Antibacterial Agent?
- 2.3 Antiviral Agents
- 2.4 Antifungal Agents
- Chapter 3. Antitumor Agents
- 3.1 Introduction
- 3.2 Unsubstituted Coumarin
- 3.3 Substitution in Coumarin Nucleus
- Chapter 4. Neuroprotective Agents
- 4.1 Introduction
- 4.2 Anti-Alzheimer Agents
- Chapter 5. Antidepressing Agents
- 5.1 Introduction
- Chapter 6. Anti-Inflammatory Agents
- 6.1 Introduction
- Chapter 7. Antioxidant Agents
- 7.1 Introduction
- 7.2 Coumarin Nucleus
- 7.3 SAR by Bond Dissociation Enthalpy
- 7.4 Radical Scavenging Activity
- 7.5 Antioxidant Capacity (or Total Antioxidant Capacity)
- 7.6 Chelating Activity
- Chapter 8. Anticoagulant Agents
- 8.1 Introduction
- Chapter 9. Miscellaneous Agents
- 9.1 Dopamine Inhibatory Activity
- 9.2 DNA-PK Inhibitory Activity
- 9.3 Antipsychotic Agents
- 9.4 Tyrosinase Inhibitors
- References
- No. of pages: 190
- Language: English
- Edition: 1
- Published: August 7, 2015
- Imprint: Academic Press
- Paperback ISBN: 9780128037973
- eBook ISBN: 9780128038734
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