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Advances in Planar Lipid Bilayers and Liposomes
- 1st Edition, Volume 22 - July 30, 2015
- Editors: Aleš Iglič︎, Michael Rappolt, Chandrashekhar V. Kulkarni
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 2 8 7 8 - 0
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 2 9 1 0 - 7
The Elsevier book-series Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for a broad community of experimental and theoretical researchers studying… Read more
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Request a sales quoteThe Elsevier book-series Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for a broad community of experimental and theoretical researchers studying cell membranes, lipid model membranes and lipid self-assemblies from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature and find their application in the formulation of biomimetic model membranes and in the design of artificial dispersion of liposomes. Moreover, lipids self-assemble into a wide range of other structures including micelles and the liquid crystalline hexagonal and cubic phases. Consensus has been reached that curved membrane phases do play an important role in nature as well, especially in dynamic processes such as vesicles fusion and cell communication. Self-assembled lipid structures have enormous potential as dynamic materials ranging from artificial lipid membranes to cell membranes, from biosensing to controlled drug delivery, from pharmaceutical formulations to novel food products to mention a few. An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.
- The APLBL book series gives a survey on recent theoretical as well as experimental results on lipid micro and nanostructures.
- In addition, the potential use of the basic knowledge in applications like clinically relevant diagnostic and therapeutic procedures, biotechnology, pharmaceutical engineering and food products is presented.
- An assortment of chapters in APLBL represents both an original research as well as comprehensives reviews written by world leading experts and young researchers.
experts in the field of chemistry, physics and biology of lipid micro- and nano-structures and biological membranes, and a podium for non-specialists working on the interdisciplinary front
- Preface
- Chapter One: Stimuli-Sensitive Liposomes: Lipids as Gateways for Cargo Release
- Abstract
- 1 Introduction
- 2 Currently Available Nanosystems for On-Demand Cargo Release
- 3 Triggering Solely Based on the Properties of the Lipids
- 4 Clinical Status of Triggerable Liposomes and Future Considerations
- Acknowledgments
- Chapter Two: Effect of Lipid Bilayer Composition on Membrane Protein Association
- Abstract
- 1 Introduction
- 2 Computational Methods to Analyze Association
- 3 Association of Single Transmembrane Helices
- 4 GPCR Organization
- 5 A Model for Lipid-Dependent Modulation of Membrane Protein Organization
- Chapter Three: Biomembrane Organization and Function: The Decisive Role of Ordered Lipid Domains
- Abstract
- 1 Why Are Membrane Ordered Domains a Current Research Topic?
- 2 Why Do Lipids Form Ordered Domains?
- 3 What Is the Relevance of Planar Lipid Bilayers and Liposomes for the Study of Ordered Domains?
- 4 How to Better Understand Ordered Domains and Their Function in Cell Membranes?
- 5 What About Bioelectroactive Molecules and Their Redox Behavior?
- 6 Why Study Biomembrane Ordered Domains? An Intriguing Coincidence Between In Vitro and In Vivo Studies
- 7 Concluding Remarks
- Acknowledgments
- Chapter Four: Membrane-Bound Conformations of Antimicrobial Agents and Their Modes of Action
- Abstract
- 1 Introduction
- 2 Models of Antimicrobial Action
- 3 Antimicrobial Agents with Peptide Backbone
- 4 Antimicrobial Agents with Polymer Backbones
- 5 Antimicrobial Polymers with Rigid Backbone
- 6 Discussion
- Chapter Five: Phenomenology Based Multiscale Models as Tools to Understand Cell Membrane and Organelle Morphologies
- Abstract
- 1 Introduction
- 2 Phenomenological Theories for Membranes
- 3 Membrane Remodeling Events as Equilibrium and Nonequilibrium Processes
- 4 Nematic Membrane Model for Protein Driven Membrane Remodeling
- 5 Active Membrane Models for Curvature Fluctuations
- 6 Conclusions
- Acknowledgments
- Chapter Six: Membrane Microvesiculation and its Suppression
- Abstract
- 1 Membrane Curvature and Cell Shape
- 2 Membranous Nanostructures and the Fluid Crystal Mosaic Model
- 3 Mechanisms of Micro and Nanovesiculation
- 4 Observation of Membrane Vesiculation on Giant Phospholipid Vesicles
- 5 Attractive Mediated Interaction Between Membranes is Subject to Bridging Mechanism and Orientational Ordering of Mediating Molecules
- 6 Stability of Narrow Necks
- 7 Suppression of Membrane Vesiculation in Cells
- 8 Clinical Implications of Membrane Budding Suppression
- Index
- No. of pages: 230
- Language: English
- Edition: 1
- Volume: 22
- Published: July 30, 2015
- Imprint: Academic Press
- Hardback ISBN: 9780128028780
- eBook ISBN: 9780128029107
AI
Aleš Iglič︎
MR
Michael Rappolt
CK