Advances in Mitochondrial Drug Delivery
From Molecular Mechanisms to Clinical Translation
- 1st Edition - March 1, 2027
- Latest edition
- Editor: Prashant Kesharwani
- Language: English
Advances in Mitochondrial Drug Delivery: From Molecular Mechanisms to Clinical Translation addresses the critical need for a comprehensive resource on mitochondrial-targeted drug d… Read more
Description
Description
Key features
Key features
- Provides a comprehensive exploration of mitochondrial targeting strategies from fundamentals to advanced applications
- Analyses novel drug delivery systems utilizing mitochondria for therapeutic benefits
- Organizes content with illustrative figures and tables enhancing reader comprehension and engagement
- Addresses current challenges in clinical translation and regulatory aspects of mitochondrial drug delivery
Readership
Readership
Table of contents
Table of contents
1. Introduction to Mitochondrial Structure and Function
2. Mitochondrial Dysfunction and Its Role in Disease Pathophysiology
3. Role of Mitochondria in Cancer Metabolism
4. Cellular and Subcellular Targeting: Challenges in Mitochondrial Drug Delivery
5. Mechanisms of Mitochondrial Targeting
6. Mitochondrial Biogenesis and Metabolic Reprogramming
SECTION 2: Mitochondria-Targeted Drug Delivery Strategies
7. Concept of Mito-Porters, Mitochondriotropics, and Mitocans
8. Lipophilic Cation-Based Mitochondrial Targeting
9. Mitochondria-Penetrating Peptides (MPPs) and Peptide-Based Targeting
10. Nanoparticle-Based Mitochondrial Targeting
11. Mitochondria-Targeted Prodrugs and Small Molecule Therapeutics
12. Transporter-Mediated Mitochondrial Drug Delivery
13. Mitochondria-Targeted Gene Therapy and RNA Delivery
14. Stimuli-Responsive Mitochondria-Targeted Drug Delivery
15. Mitochondria-Targeted Photodynamic and Photothermal Therapy
SECTION 3: Applications of Mitochondria-Targeted Therapeutics
16. Mitochondria-Targeted Drug Delivery for Cancer Therapy
17. Mitochondria-Targeted Therapeutics for Neurodegenerative Diseases
18. Mitochondria in Cardiovascular and Metabolic Diseases
19. Mitochondria-Targeted Approaches for Infectious Diseases
20. Emerging Therapies for Mitochondrial Genetic Disorders
SECTION 4: Future Directions, Clinical Translation, and Regulatory Aspects
21. Ethical Considerations in Mitochondrial Gene Therapy
22. Advances in Mitochondria-Targeted Drug Discovery and Development
23. Clinical Translation, Regulatory Challenges, and Future Perspectives
Product details
Product details
- Edition: 1
- Latest edition
- Published: March 1, 2027
- Language: English
About the editor
About the editor
PK
Prashant Kesharwani
Dr. Prashant Kesharwani is assistant professor of Pharmaceutics at Department of Pharmaceutical Sciences, Dr. Harisingh Gour Vishwavidyalaya University, Sagar, Madhya Pradesh, India. He has more than a decade of teaching, research, and industrial experience across various countries. An overarching goal of his current research is the development of nanoengineered drug delivery systems for various diseases. He has published many articles in well-reputed journals and a large number of books. He is a recipient of many research grants from various funding bodies. He is also the recipient of several internationally acclaimed awards, such as “USERN Laureate award”, and “SERB-Ramanujan Fellowship Award”. He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of the wider community.