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Elsevier

Advances in Immunology

  • 1st Edition, Volume 172 - May 1, 2027
  • Latest edition
  • Editors: Frederick Alt, Kenneth Murphy
  • Language: English

Advances in Immunology, Volume 172, provides current research contributions in immunology, including a detailed examination of gasdermin activation mechanisms and their role in i… Read more

Description

Advances in Immunology, Volume 172, provides current research contributions in immunology, including a detailed examination of gasdermin activation mechanisms and their role in initiating membrane pore formation to execute pyroptosis. Further chapters from an international group of contributors extend the volume's coverage of immune mechanisms and disease relevance.

Key features

  • Examines the mechanisms of gasdermin activation and membrane pore formation in pyroptosis
  • Authored by leading researchers in innate immunity and cell death signaling
  • Continues Advances in Immunology's long-standing role as a core reference in the field

Readership

Immunologists and cell biologists studying innate immune signaling and cell death pathways; researchers investigating inflammasome biology and pyroptosis; molecular biologists working on membrane pore-forming mechanisms

Product details

  • Edition: 1
  • Latest edition
  • Volume: 172
  • Published: May 1, 2027
  • Language: English

About the editors

FA

Frederick Alt

Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Professor of Pediatrics and Professor of Genetics, Harvard Medical School, Boston, MA, USA

KM

Kenneth Murphy

Kenneth M. Murphy works in Washington University School of Medecine, USA.
Affiliations and expertise
Washington University School of Medecine, USA