Advances in Immunology
- 1st Edition, Volume 160 - November 24, 2023
- Editors: Frederick W. Alt, Kenneth Murphy
- Language: English
- Hardback ISBN:9 7 8 - 0 - 4 4 3 - 2 2 2 3 6 - 8
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 2 2 3 7 - 5
Advances in Immunology, Volume 160, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in… Read more
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Request a sales quoteAdvances in Immunology, Volume 160, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology.
- Presents current developments and comprehensive reviews in immunology
- Provides the latest in a longstanding and respected serial on the subject matter
- Focuses on recent advances in t cells and HIV infection
Immunologists and infectious disease specialists, cell biologists and hematologists
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Chapter One: Recent advances in immunopeptidomic-based tumor neoantigen discovery
- Abstract
- 1 Immune recognition of tumor antigens
- 2 Categories of tumor antigens
- 3 Methods for tumor neoantigen identification
- 4 Recent advances in MS-based neoantigen identification
- 5 Conclusions
- References
- Chapter Two: How B cells drive T-cell responses: A key role for cross-presentation of antibody-targeted antigens
- Abstract
- 1 Introduction
- 2 Specific antibodies can enhance antigen presentation and T-cell priming
- 3 Receptors for antigen–antibody immune complexes
- 4 Central role of dendritic cells
- 5 Intracellular processing of antigen–antibody immune complexes by dendritic cells
- 6 Storage compartments facilitate sustained cross-presentation after uptake of antigen–antibody immune complexes
- 7 Relevance of antibody-mediated cross-presentation in cancer immunology and therapy
- 8 Summary and concluding remarks
- References
- Chapter Three: Post-transcriptional regulation of myeloid cell-mediated inflammatory responses
- Abstract
- 1 Introduction
- 2 Alternative splicing in myeloid cells
- 3 Regulation of mRNA stability
- 4 Translation regulation in macrophages
- 5 Post-transcriptional study in innate immunity: The limit, prospect and therapeutic implication
- References
- Chapter Four: Immunometabolism of dendritic cells in health and disease
- Abstract
- 1 Introduction
- 2 Metabolic modulation of DC activation and migration
- 3 Metabolic modulation of the immunogenic and tolerogenic functions of DCs
- 4 Metabolic modulation of DC biology in tumors
- 5 Metabolic modulation of DCs in metabolic diseases
- 6 Metabolic crosstalk between DCs and gut microbiota
- 7 Conclusions and future perspectives
- References
- No. of pages: 198
- Language: English
- Edition: 1
- Volume: 160
- Published: November 24, 2023
- Imprint: Academic Press
- Hardback ISBN: 9780443222368
- eBook ISBN: 9780443222375
FA
Frederick W. Alt
Frederick W. Alt is a Howard Hughes Medical Institute (HHMI) Investigator and Director of the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital (BCH). He is the Charles A. Janeway Professor of Pediatrics and Professor of Genetics at Harvard Medical School. He works on elucidating mechanisms that generate antigen receptor diversity and, more generally, on mechanisms that generate and suppress genomic instability in mammalian cells, with a focus on the immune and nervous systems. Recently, his group has developed senstive genome-wide approaches to identify mechanisms of DNA breaks and rearrangements in normal and cancer cells. He has been elected to the U.S. National Academy of Sciences, the U.S. National Academy of Medicine, and the European Molecular Biology Organization. His awards include the Albert Szent-Gyorgyi Prize for Progress in Cancer Research, the Novartis Prize for Basic Immunology, the Lewis S. Rosensteil Prize for Distinugished work in Biomedical Sciences, the Paul Berg and Arthur Kornberg Lifetime Achievement Award in Biomedical Sciences, and the William Silan Lifetime Achievement Award in Mentoring from Harvard Medical School.
Affiliations and expertise
Investigator and Director, Program in Cellular and Molecular Medicine, Howard Hughes Medical Institute Research Laboratories, The Children's Hospital, Boston, MA, USAKM
Kenneth Murphy
Kenneth M. Murphy works in Washington University School of Medecine, USA.
Affiliations and expertise
Washington University School of Medecine, USARead Advances in Immunology on ScienceDirect