Advances in Genetics
- 1st Edition, Volume 32 - May 11, 1995
- Imprint: Academic Press
- Editors: Jeffrey C. Hall, Jay C. Dunlap, Theodore Friedmann, Francesco Giannelli
- Language: English
- eBook ISBN:9 7 8 - 0 - 0 8 - 0 5 6 8 1 9 - 5
Volume 32 of Advances in Genetics: Incorporating Molecular Genetic Medicine focuses on important and fast moving subjects in modern human genetics and medicine. This volume also m… Read more
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Request a sales quoteVolume 32 of Advances in Genetics: Incorporating Molecular Genetic Medicine focuses on important and fast moving subjects in modern human genetics and medicine. This volume also marks the new collaboration with Associate Editors Dr. Theodore Friedmann and Dr. Francesco Giannelli. Chapter 1 considers the potential effectiveness and consequences of gene therapy on subjects over time. Chapter 2 discusses recent research on Gaucher's disease, the first disorder to demonstrate the clinical benefits of enzyme replacement therapy. Chapter 3 describes current findings on diabetes, a disease difficult to conquer due to its variety and its genetic and environmental causes. The major forms of hemophilia and the need for alternative therapies are discussed in Chapter 4. Chapter 5 presents hypercholesterolemia as a model for understanding the causes and treatments of human diseases on a molecular level. Chapter 6 probes the basic genetic defects behind phenylketonuria, as well as the possibilities for genetic correction. Chapter 7 covers the fascinating terminal structures of human chromosomes.In the Foreword to Volume 32, Drs. Friedmann and Giannelli suggest: "Progress toward a thorough characterization of the human genome is stunningly rapid and exceeding many of its earliest expectations. Disease-related genes will be falling from the skies faster than we can understand them, and mechanisms responsible for the pathogenesis of disease will be illuminated more quickly and readily than ever before. "With comprehensive and timely reviews, Advances in Genetics incorporating Molecular Genetic Medicine offers with every volume further insight into this expanding field of medicine, supplementing the continued expert coverage of all other areas of genetics pioneered by Advances in Genetics.
@introbul:Key Features@bul:* Presents technical and historical overviews of molecular biology applied to disease detection, diagnosis, and treatment* Chronicles the continuing explosion of knowledge in molecular genetic medicine by highlighting current approaches to understanding human illness* Documents the revolution in human and molecular genetics leading to a new field of medicine* Volume 32 marks new collaboration with Associate Editors Dr. Theodore Friedmann and Dr. Francesco Giannelli
AUDIENCE: Researchers and students of all aspects of genetics, molecular, cell and developmental biology, and human genetic medicine. Academic, medical, industry, and library markets.
J.C. Hall and J.C. Dunlap, Foreword. T. Friedmann and F. Giannelli, Preface.F.D. Ledley, After Gene Therapy: Issues in Long-Term Clinical Follow-Up and Care.E. Beutler, Gaucher Disease.T.S. Pillay,W.J. Langlois, and J.M. Olefsky, The Genetics of Non-insulin-Dependent Diabetes Mellitus.P.M. Green, J.A. Naylor, and F. Giannelli, The Hemophilias.T.P. Knecht and C.K. Glass, The Influence of Molecular Biology on our Understanding of Lipoprotein Metabolism and the Pathobiology of Atherosclerosis.R.C. Eisensmith and S.L.C. Woo, Molecular Genetics of Phenylketonuria: From Molecular Anthropology to Gene Therapy.N.J. Royle, The Proterminal Regions and Telomeres of Human Chromosomes.References.Subject Index.
- Edition: 1
- Volume: 32
- Published: May 11, 1995
- No. of pages (eBook): 322
- Imprint: Academic Press
- Language: English
- eBook ISBN: 9780080568195
JH
Jeffrey C. Hall
Affiliations and expertise
Brandeis University, Waltham, MA, USAJD
Jay C. Dunlap
Affiliations and expertise
The Geisel School of Medicine, Dartmouth, NH, USATF
Theodore Friedmann
School of Medicine, University of California at San Diego, USA
Affiliations and expertise
School of Medicine, University of California at San Diego, USAFG
Francesco Giannelli
Affiliations and expertise
United Medical and Dental Schools of Guy’s and St. Thomas’ Hospitals, London, U.K.Read Advances in Genetics on ScienceDirect