Advances in Clinical Chemistry
- 1st Edition, Volume 54 - June 3, 2011
- Latest edition
- Editor: Gregory S. Makowski
- Language: English
Volume 54 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors a… Read more
Volume 54 in the internationally acclaimed Advances in Clinical Chemistry contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics, ranging from basic biochemical exploration to cutting-edge microarray technology.
- Leading experts from academia and clinical laboratory science
- Volume emphasizes novel laboratory advances with application to clinical laboratory diagnostics and practical basic science studies
Biochemists and clinical biochemists
- Preface
- Heat-shock proteins in cardiovascular disease
- Abbreviations
- 2. Introduction
- 3. Atherogenesis and Possible Stimuli of Inducible HSPs
- 4. HSPs/Anti-HSPs as Biomarkers of Atherothrombosis
- 5. Molecular Mechanisms: Bystanders or Actors?
- 6. HSP as Therapeutic Targets in CVD/Atherothrombosis
- 7. Conclusions
- Acknowledgments
- Polyamines in cancer
- Abbreviations
- 2. Introduction
- 3. Overview of Polyamine Regulation
- 4. Deregulation of Polyamines in Cancer
- 5. Genetic Variability in ODC Affecting Carcinogenesis
- 6. EIF5A and Cancer
- 7. Chemoprevention Strategies Within Polyamine Pathway
- Acknowledgments
- Acquired hemophilia A
- 2. Introduction
- 3. Pathogenesis
- 4. Laboratory Diagnosis
- 5. Conclusions
- Acknowledgments
- Hypobetalipoproteinemia
- Abbreviations
- 2. Introduction
- 3. Pathways of apoB-Containing Lipoproteins Production
- 4. Dominant Forms of Primary HBL
- 5. Recessive Forms of Primary HBL
- 6. Primary Orphan FHBL
- 7. Spectrum of Clinical Manifestations in Primary HBL
- 8. Main Clinical Issues of FHBL
- 9. Secondary Hypobetalipoproteinemias
- 10. Conclusions
- Addendum
- Acknowledgment
- Sm peptides in differentiation of autoimmune diseases
- 2. Introduction
- 3. Systemic Lupus Erythematosus
- 4. Mixed Connective Tissue Disease
- 5. Biochemical Aspects of the Sm Antigen
- 6. Characteristics of Anti-Sm Antibodies
- 7. Detection of Anti-Sm Antibodies
- 8. Clinical Association of Anti-Sm Antibodies
- 9. Meta-Analysis of Anti-Sm Antibodies
- 10. Genesis of Anti-Sm Antibodies
- 11. (Sm) Peptides as Antigens
- 12. Summary and Conclusion
- 13. Take Home Messages
- Aromatase activity and bone loss
- 2. Introduction
- 3. Aromatase and Sources of Estrogen Production
- 4. The Aromatase Gene and Its Tissue-Specific Regulation
- 5. Aromatase Deficiency and the Bone
- 6. Skeletal Consequences of Aromatase Excess
- 7. Threshold Estradiol Hypothesis for Skeletal Sufficiency
- 8. Variability in the Level of Aromatase Activity: Effects on Bone Metabolism
- 9. Summary and Conclusions
- Biochemistry of adolescent idiopathic scoliosis
- 2. Introduction
- 3. Bone Biochemical Parameters
- 4. Hormones
- 5. Trace Elements
- 6. Hematological Parameters—Platelets
- 7. Melatonin
- 8. Conclusions
- Edition: 1
- Latest edition
- Volume: 54
- Published: June 3, 2011
- Language: English
GM
Gregory S. Makowski
Dr Gregory S Makowski is a board-certified clinical chemist and fellow of the National Academy of Clinical Biochemistry. Following receipt of his PhD in Biochemistry from the University of Connecticut Storrs, he pursued post-doctoral studies at the University of Connecticut School of Medicine in Farmington that culminated in joint appointments in the School of Medicine and the Department of Laboratory Medicine at John Dempsey Hospital. He has numerous clinical and basic science publications and serves on various scientific and editorial boards. He is actively engaged in the training of Pathology residents and fellows in the Department of Pathology and Laboratory Medicine at Hartford Hospital. He currently serves as Vice President Clinical Laboratory Services Hartford HealthCare in Connecticut.
Affiliations and expertise
Vice President and Chief Scientific Officer, Clinical Laboratory Partners, Newington, CT, USARead Advances in Clinical Chemistry on ScienceDirect