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Advances in Cholestatic Liver Disease, An Issue of Clinics in Liver Disease

  • 1st Edition, Volume 30-3 - July 24, 2026
  • Latest edition
  • Editors: Gidgeon Hirschfield, Aliya Gulamhusein
  • Language: English

In this issue of Clinics in Liver Disease, guest editors Drs. Gidgeon Hirschfield and Aliya Gulamhusein bring their considerable expertise to the topic of Advances in Cholestat… Read more

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Description

In this issue of Clinics in Liver Disease, guest editors Drs. Gidgeon Hirschfield and Aliya Gulamhusein bring their considerable expertise to the topic of Advances in Cholestatic Liver Disease. Top experts discuss the pathophysiological basis to chronic cholestasis alongside a review of the patient journey from diagnostic approach, differential causes, symptom burden, complications, and end stage liver disease.

Key features

  • Contains 13 relevant, practice-oriented topics including the scientific basis of cholestatic liver disease and its symptom complex; overlap syndromes with PBC and PSC; genetic cholestatic syndromes; general hepatology concerns for the patient with cholestatic liver disease; PSC-associated cholangiocarcinoma; and more
  • Provides in-depth clinical reviews on advances in cholestatic liver disease, offering actionable insights for clinical practice
  • Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews

Readership

Hepatologists

Table of contents

The Scientific Basis of Cholestatic Liver Disease and Its Symptom Complex
General Hepatology Concerns for the Patient with Cholestatic Liver Disease
The Diagnostic Pathway for Patients with Cholestatic Liver Disease
Cholestatic Pruritus: A Review of Pathophysiology, Clinical Manifestations, and Therapeutic Landscape
Biliary Atresia: A Focus on the Patient Journey from Diagnosis to Transplant
Genetic Cholestasis Syndromes
Intrahepatic Cholestasis of Pregnancy
Primary Biliary Cholangitis
Primary Sclerosing Cholangitis
“Overlap” Syndromes in Autoimmune Liver Disease: Definitions, Clinical Challenges and Future Directions
Immunoglobulin G4–Related Sclerosing Cholangitis: A Review
Perihilar Cholangiocarcinoma in Primary Sclerosing Cholangitis
Recurrence of Primary Biliary Cholangitis and Primary Sclerosing Cholangitis after Liver Transplantation: Current Evidence and Clinical Implications

Product details

  • Edition: 1
  • Latest edition
  • Volume: 30-3
  • Published: July 24, 2026
  • Language: English

About the editors

GH

Gidgeon Hirschfield

Affiliations and expertise
Director of the Autoimmune Liver Disease Program, UHN Francis Family Liver Clinic and Toronto Centre for Liver Disease, Lily and Terry Horner Chair in Autoimmune Liver Disease Research, University Health Network, University of Toronto, Toronto, Ontario, Canada

AG

Aliya Gulamhusein

Affiliations and expertise
Assistant Professor and Clinician Investigator, Division of Gastroenterology at the University of Toronto, Staff Hepatologist, Toronto Centre for Liver Disease, Francis Family Liver Clinic, Canada